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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735908
Species: Mus musculus
RGD Object: Gene
Symbol: Chrna2
Name: cholinergic receptor nicotinic alpha 2 subunit
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrna2increases methylationISOChrna2 (Rattus norvegicus)6480464CTDGlyphosate results in increased methylation of CHRNA2 genePMID:31011160
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