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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735729
Species: Homo sapiens
RGD Object: Gene
Symbol: FOS
Name: Fos proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:9195
Term: Soman
Definition: A phosphonic ester that has formula C7H16FO2P.
Chemical ID: MESH:D012999
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FOSaffects expressionISOFos (Rattus norvegicus)6480464CTDSoman affects the expression of FOS mRNAPMID:21971501
FOSincreases expressionISOFos (Rattus norvegicus)6480464CTDSoman results in increased expression of FOS mRNA; Soman results in increased expression of FOS proteinPMID:19281266 PMID:21971501 PMID:26205086
FOSmultiple interactionsISOFos (Rattus norvegicus)6480464CTD[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased expression of FOS protein]PMID:21971501
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