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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735621
Species: Homo sapiens
RGD Object: Gene
Symbol: CXCL2
Name: C-X-C motif chemokine ligand 2
Acc ID: CHEBI:34718
Term: 1-chloro-2,4-dinitrobenzene
Definition: A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Chemical ID: MESH:D004137
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL2increases expressionEXP 6480464CTDDinitrochlorobenzene results in increased expression of CXCL2 mRNAPMID:20146380
CXCL2increases expressionISOCxcl2 (Mus musculus)6480464CTDDinitrochlorobenzene results in increased expression of CXCL2 mRNA; Dinitrochlorobenzene results in increased expression of CXCL2 proteinPMID:16675337 PMID:19647056 PMID:23178550 PMID:28826779
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