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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735592
Species: Mus musculus
RGD Object: Gene
Symbol: Ppp3r1
Name: protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Acc ID: CHEBI:17933
Term: calcidiol
Definition: A hydroxycalciol that is calciol in which the hydrogen at position 25 has been replaced by a hydroxy group. A prehormone resulting from the oxidation of calciol in the liver, it is further hydroxylated in the kidney to give calcitriol, the active form of vitamin D3.
Chemical ID: MESH:D002112
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppp3r1decreases expressionISOPpp3r1 (Rattus norvegicus)6480464CTDCalcifediol deficiency results in decreased expression of PPP3R1 mRNAPMID:17293106
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