GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CDKN1A | increases expression | EXP | | 6480464 | CTD | tributyltin results in increased expression of CDKN1A mRNA; tributyltin results in increased expression of CDKN1A protein | PMID:28011154 PMID:36319700 | CDKN1A | multiple interactions | EXP | | 6480464 | CTD | 2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [tributyltin results in increased expression of CDKN1A protein]; pyrazolanthrone inhibits the reaction [tributyltin results in increased expression of CDKN1A protein] | PMID:36319700 | CDKN1A | decreases expression | ISO | Cdkn1a (Mus musculus) | 6480464 | CTD | tributyltin results in decreased expression of CDKN1A mRNA | PMID:31939706 | CDKN1A | increases expression | ISO | Cdkn1a (Mus musculus) | 6480464 | CTD | tributyltin results in increased expression of CDKN1A protein | PMID:36319700 | | ||||||||||||||||||||||
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