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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735336
Species: Mus musculus
RGD Object: Gene
Symbol: Akt1
Name: thymoma viral proto-oncogene 1
Acc ID: CHEBI:5299
Term: Geniposide
Definition: A terpene glycoside that has formula C17H24O10.
Chemical ID: MESH:C007835
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1multiple interactionsISOAkt1 (Rattus norvegicus)6480464CTDgeniposide inhibits the reaction [Palmitic Acid results in decreased phosphorylation of AKT1 protein]PMID:22819839
Akt1multiple interactionsISOAKT1 (Homo sapiens)6480464CTD[geniposide co-treated with Hydrogen Peroxide] results in increased expression of AKT1 mRNA; geniposide inhibits the reaction [Hydrogen Peroxide results in decreased expression of AKT1 protein]PMID:37940031
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