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GENE - TERM ANNOTATION REPORT

RGD ID: 735138
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tlr2
Name: toll-like receptor 2
Acc ID: DOID:9004484
Term: Sepsis
Definition: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Definition Source(s): MESH:D018805
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tlr2 IEP 1302750RGDassociated with Burns;mRNA:increased expression:liver, lung, kidney 
Tlr2 IEP 2312497RGDassociated with Liver Diseases;mRNA:increased expression:liver 
Tlr2 IEP 2312732RGD  
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