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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734192
Species: Mus musculus
RGD Object: Gene
Symbol: Gpt
Name: glutamic pyruvic transaminase, soluble
Acc ID: CHEBI:9434
Term: telmisartan
Definition: A member of the class of benzimidazoles used widely in the treatment of hypertension.
Chemical ID: MESH:C084178
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gptmultiple interactionsISOGpt (Rattus norvegicus)6480464CTDTelmisartan inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]; Telmisartan inhibits the reaction [Methotrexate results in increased expression of and results in increased secretion of GPT protein]PMID:26929000 PMID:27269004
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