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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733567
Species: Mus musculus
RGD Object: Gene
Symbol: Tfam
Name: transcription factor A, mitochondrial
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tfamdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of TFAM mRNAPMID:26063408
Tfamincreases expressionEXP 6480464CTDbisphenol A results in increased expression of TFAM mRNAPMID:25594700
Tfamdecreases expressionISOTfam (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of TFAM mRNAPMID:23328667 PMID:24105817
Tfamincreases expressionISOTFAM (Homo sapiens)6480464CTDbisphenol A results in increased expression of TFAM proteinPMID:37567409
Tfamincreases expressionISOTfam (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of TFAM mRNA; bisphenol A results in increased expression of TFAM proteinPMID:25181051 PMID:34947998 PMID:35887390
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