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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733567
Species: Mus musculus
RGD Object: Gene
Symbol: Tfam
Name: transcription factor A, mitochondrial
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tfamaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of TFAM mRNAPMID:21570461
Tfamdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of TFAM mRNAPMID:24058054
Tfamincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of TFAM mRNAPMID:16960034
Tfamaffects expressionISOTFAM (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of TFAM mRNAPMID:22574217
Tfamdecreases expressionISOTFAM (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of TFAM mRNAPMID:17101203
Tfamincreases expressionISOTfam (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of TFAM mRNAPMID:16960034 PMID:32109520
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