GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | BECN1 | increases expression | EXP | | 6480464 | CTD | Silicon Dioxide results in increased expression of BECN1 protein | PMID:32061152 | BECN1 | multiple interactions | EXP | | 6480464 | CTD | 3-methyladenine inhibits the reaction [Silicon Dioxide promotes the reaction [PIK3C3 protein binds to BECN1 protein]]; ABT-737 inhibits the reaction [Silicon Dioxide promotes the reaction [BCL2 protein binds to BECN1 protein]]; Silicon Dioxide promotes the reaction [BCL2 protein binds to BECN1 protein]; Silicon Dioxide promotes the reaction [PIK3C3 protein binds to BECN1 protein] | PMID:32061152 | BECN1 | increases expression | ISO | Becn1 (Rattus norvegicus) | 6480464 | CTD | Silicon Dioxide analog results in increased expression of BECN1 protein; Silicon Dioxide results in increased expression of BECN1 mRNA | PMID:27613482 PMID:33749107 | BECN1 | increases expression | ISO | Becn1 (Mus musculus) | 6480464 | CTD | Silicon Dioxide results in increased expression of BECN1 mRNA; Silicon Dioxide results in increased expression of BECN1 protein | PMID:33232774 | BECN1 | multiple interactions | ISO | Becn1 (Rattus norvegicus) | 6480464 | CTD | Asian ginseng inhibits the reaction [Silicon Dioxide results in increased expression of BECN1 mRNA] | PMID:33749107 | BECN1 | multiple interactions | ISO | Becn1 (Mus musculus) | 6480464 | CTD | GAS6 gene mutant form inhibits the reaction [Silicon Dioxide results in increased expression of BECN1 mRNA]; GAS6 gene mutant form inhibits the reaction [Silicon Dioxide results in increased expression of BECN1 protein]; MERTK gene mutant form inhibits the reaction [Silicon Dioxide results in increased expression of BECN1 protein] | PMID:33232774 | | ||||||||||||||||||||||
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