GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CAT | increases expression | EXP | | 6480464 | CTD | Thioctic Acid results in increased expression of CAT mRNA | PMID:23649336 | CAT | multiple interactions | EXP | | 6480464 | CTD | [Paraquat co-treated with Thioctic Acid] results in increased expression of CAT mRNA | PMID:23649336 | CAT | increases activity | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | Thioctic Acid results in increased activity of CAT protein | PMID:19368863 PMID:19715735 | CAT | multiple interactions | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | [acetovanillone results in increased susceptibility to Thioctic Acid] inhibits the reaction [Mitogens results in decreased activity of CAT protein]; Succimer promotes the reaction [Thioctic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]]; Thioctic Acid inhibits the reaction [Acetic Acid results in decreased activity of CAT protein]; Thioctic Acid inhibits the reaction [aroclor 1260 results in decreased activity of CAT protein]; Thioctic Acid inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; Thioctic Acid inhibits the reaction [Ivermectin results in decreased activity of CAT protein]; Thioctic Acid inhibits the reaction [Lipopolysaccharides results in decreased activity of CAT protein]; Thioctic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Thioctic Acid inhibits the reaction [Valproic Acid results in decreased activity of CAT protein]; Thioctic Acid promotes the reaction [acetovanillone inhibits the reaction [Mitogens results in decreased activity of CAT protein]]; Thioctic Acid promotes the reaction [Succimer inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]] | PMID:15998567 PMID:19699728 PMID:22623521 PMID:26276312 PMID:27581792 PMID:28880400 PMID:29214690 PMID:29760339 PMID:32662911 | CAT | multiple interactions | ISO | Cat (Mus musculus) | 6480464 | CTD | Thioctic Acid inhibits the reaction [Cisplatin results in decreased expression of CAT mRNA]; Thioctic Acid inhibits the reaction [Dietary Fats results in decreased activity of CAT protein]; Thioctic Acid inhibits the reaction [Silicon results in decreased activity of CAT protein]; Thioctic Acid inhibits the reaction [Silicon results in decreased expression of CAT mRNA] | PMID:21763304 PMID:27260466 PMID:34252510 | | ||||||||||||||||||||||
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