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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732053
Species: Mus musculus
RGD Object: Gene
Symbol: Slco1b2
Name: solute carrier organic anion transporter family, member 1b2
Acc ID: CHEBI:16359
Term: cholic acid
Definition: A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.
Chemical ID: MESH:D019826
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slco1b2increases expressionEXP 6480464CTDCholic Acid results in increased expression of SLCO1B2 mRNAPMID:25582706
Slco1b2increases uptakeEXP 6480464CTDSLCO1B2 protein results in increased uptake of Cholic AcidPMID:20949553
Slco1b2increases expressionISOSLCO1B3 (Homo sapiens)6480464CTDCholic Acid results in increased expression of SLCO1B3 mRNAPMID:25055961
Slco1b2increases uptakeISOSLCO1B3 (Homo sapiens)6480464CTDSLCO1B3 protein results in increased uptake of Cholic AcidPMID:16534140
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