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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731724
Species: Homo sapiens
RGD Object: Gene
Symbol: PSEN1
Name: presenilin 1
Acc ID: CHEBI:27266
Term: valine
Definition: A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isopropyl group.
Chemical ID: MESH:D014633
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PSEN1multiple interactionsISOPsen1 (Mus musculus)6480464CTD[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Valine; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Valine]PMID:39172838
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