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GENE - TERM ANNOTATION REPORT

RGD ID: 731382
Species: Homo sapiens
RGD Object: Gene
Symbol: KIT
Name: KIT proto-oncogene, receptor tyrosine kinase
Acc ID: DOID:9002762
Term: Ovarian Neoplasms
Definition: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
Definition Source(s): MESH:D010051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KITdisease_progressionIEP 2292422RGDadvanced serous ovarian carcinoma; protein:increased expression:tumor:expression correlated with disease progression after first-line chemotherapy (i.e. chemotherapy resistance), p=0.029 
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