GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | increases expression | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | nickel sulfate results in increased expression of VEGFA mRNA | PMID:18832182 | Vegfa | increases secretion | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | nickel sulfate results in increased secretion of VEGFA protein | PMID:18832182 | Vegfa | multiple interactions | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of VEGFA mRNA; [nickel sulfate co-treated with Dinoprostone] results in increased secretion of VEGFA protein; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of VEGFA protein]; macrophage stimulatory lipopeptide 2 promotes the reaction [nickel sulfate results in increased secretion of VEGFA protein]; PTGS2 protein promotes the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of VEGFA protein] | PMID:18832182 | | ||||||||||||||||||||||
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