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GENE - TERM ANNOTATION REPORT

RGD ID: 731027
Species: Homo sapiens
RGD Object: Gene
Symbol: BDNF
Name: brain derived neurotrophic factor
Acc ID: DOID:4483
Term: rhinitis
Definition: A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Rhinitis "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BDNFsusceptibilityIAGP 8655967RGDDNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human) 
BDNF ISOBdnf (Rattus norvegicus)4891116RGDmRNA:increased expression:nasal cavity epithelium 
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