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GENE - TERM ANNOTATION REPORT

RGD ID: 731018
Species: Homo sapiens
RGD Object: Gene
Symbol: KDR
Name: kinase insert domain receptor
Acc ID: DOID:684
Term: hepatocellular carcinoma
Definition: A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver. (DO)
Definition Source(s): http://cancergenome.nih.gov/cancersselected/LiverHepatocellularCarcinoma "DO" "DO", http://en.wikipedia.org/wiki/Hepatocellular_carcinoma "DO" "DO", http://www.omim.org/entry/114550 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KDR IAGP 126848814RGDassociated with alcoholic liver cirrhosis;DNA:SNP: :1416A>T (human) 
KDRtreatmentIAGP 126848806RGDDNA:SNPs: :rs1870377, rs2071559, rs2305948 (human) 
KDRdisease_progressionIEP 126848810RGDprotein:increased expression:liver 
KDRdisease_progressionIEP 126848812RGDprotein:decreased expression:liver 
KDRtreatmentIEP 126848813RGD  
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