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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730899
Species: Mus musculus
RGD Object: Gene
Symbol: Ereg
Name: epiregulin
Acc ID: CHEBI:29866
Term: arsenite(3-)
Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid.
Chemical ID: MESH:C015001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eregincreases expressionEXP 6480464CTDarsenite results in increased expression of EREG mRNAPMID:15894712
Eregmultiple interactionsEXP 6480464CTD[arsenite co-treated with Benzo(a)pyrene] results in increased expression of EREG mRNAPMID:15894712
Eregdecreases expressionISOEREG (Homo sapiens)6480464CTDarsenite results in decreased expression of EREG mRNAPMID:19716837
Eregincreases methylationISOEREG (Homo sapiens)6480464CTDarsenite results in increased methylation of EREG promoterPMID:19716837
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