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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730893
Species: Mus musculus
RGD Object: Gene
Symbol: Nfkb1
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Acc ID: CHEBI:30742
Term: ethylene glycol
Definition: A 1,2-glycol compound produced via reaction of ethylene oxide with water.
Chemical ID: MESH:D019855
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkb1increases expressionISONfkb1 (Rattus norvegicus)6480464CTDEthylene Glycol results in increased expression of NFKB1 proteinPMID:16284884
Nfkb1multiple interactionsISONfkb1 (Rattus norvegicus)6480464CTDbenazepril inhibits the reaction [Ethylene Glycol results in increased expression of NFKB1 protein]; Losartan inhibits the reaction [Ethylene Glycol results in increased expression of NFKB1 protein]; PD 123319 inhibits the reaction [Ethylene Glycol results in increased expression of NFKB1 protein]PMID:16284884
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