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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730872
Species: Homo sapiens
RGD Object: Gene
Symbol: SOD2
Name: superoxide dismutase 2
Acc ID: CHEBI:6809
Term: methamphetamine
Definition: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
Chemical ID: MESH:D008694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SOD2increases activityEXP 6480464CTDMethamphetamine results in increased activity of SOD2 proteinPMID:25523949
SOD2increases response to substanceEXP 6480464CTDSOD2 gene polymorphism results in increased susceptibility to MethamphetaminePMID:16807759
SOD2multiple interactionsEXP 6480464CTDPRKCD protein affects the reaction [Methamphetamine results in increased activity of SOD2 protein]PMID:25523949
SOD2increases activityISOSod2 (Mus musculus)6480464CTDMethamphetamine results in increased activity of SOD2 proteinPMID:24430743
SOD2multiple interactionsISOSod2 (Mus musculus)6480464CTDPRKCD affects the reaction [Methamphetamine results in increased activity of SOD2 protein]PMID:24430743
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