GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL2 | decreases expression | ISO | Il2 (Rattus norvegicus) | 6480464 | CTD | Irinotecan results in decreased expression of IL2 protein | PMID:16815871 | IL2 | multiple interactions | ISO | Il2 (Rattus norvegicus) | 6480464 | CTD | Ciprofloxacin inhibits the reaction [Irinotecan promotes the reaction [Mitogens results in increased expression of IL2 protein]]; Irinotecan inhibits the reaction [Mitogens results in increased expression of IL2 protein]; Irinotecan promotes the reaction [Mitogens results in increased expression of IL2 protein]; Thalidomide inhibits the reaction [Irinotecan results in decreased expression of IL2 protein]; Thalidomide promotes the reaction [Irinotecan results in decreased expression of IL2 protein] | PMID:16815871 PMID:19401694 | |
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