GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL2 | decreases expression | ISO | Il2 (Mus musculus) | 6480464 | CTD | Dextran Sulfate results in decreased expression of IL2 protein | PMID:32272095 | IL2 | increases expression | ISO | Il2 (Mus musculus) | 6480464 | CTD | Dextran Sulfate results in increased expression of IL2 mRNA | PMID:25472953 PMID:35889507 | IL2 | multiple interactions | ISO | Il2 (Mus musculus) | 6480464 | CTD | 5,7-dimethoxycoumarin inhibits the reaction [Dextran Sulfate results in increased expression of IL2 mRNA]; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL2 protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL2 protein; Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of IL2 protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL2 mRNA]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in decreased expression of IL2 protein] | PMID:21068411 PMID:25472953 PMID:32272095 PMID:35889507 | | ||||||||||||||||||||||
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