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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730846
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP8
Name: caspase 8
Acc ID: CHEBI:6015
Term: isoflurane
Definition: An organofluorine compound that has formula C3H2ClF5O.
Chemical ID: MESH:D007530
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP8increases activityISOCasp8 (Mus musculus)6480464CTDIsoflurane results in increased activity of CASP8 proteinPMID:23922164
CASP8multiple interactionsISOCasp8 (Mus musculus)6480464CTDresveratrol inhibits the reaction [Isoflurane results in increased activity of CASP8 protein]PMID:23922164
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