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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 728892
Species: Rattus norvegicus
RGD Object: Gene
Symbol: E2f1
Name: E2F transcription factor 1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
E2f1affects methylationEXP 6480464CTDAcetaminophen affects the methylation of E2F1 genePMID:29381301
E2f1increases expressionEXP 6480464CTDAcetaminophen results in increased expression of E2F1 mRNAPMID:33387578
E2f1increases expressionISOE2F1 (Homo sapiens)6480464CTDAcetaminophen results in increased expression of E2F1 mRNAPMID:22230336 PMID:25704631
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