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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 728892
Species: Rattus norvegicus
RGD Object: Gene
Symbol: E2f1
Name: E2F transcription factor 1
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
E2f1decreases expressionISOE2F1 (Homo sapiens)6480464CTDArsenic results in decreased expression of E2F1 mRNAPMID:19945496
E2f1increases expressionISOE2F1 (Homo sapiens)6480464CTDArsenic results in increased expression of E2F1 proteinPMID:23174854
E2f1multiple interactionsISOE2F1 (Homo sapiens)6480464CTDE2F1 protein affects the reaction [Arsenic results in increased expression of AURKA protein]PMID:23174854
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