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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:51403
Term: 1,4-phenylenediamine
Definition: A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus.
Chemical ID: MESH:C029728
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relaincreases phosphorylationISORELA (Homo sapiens)6480464CTD4-phenylenediamine results in increased phosphorylation of RELA proteinPMID:31226360
Relamultiple interactionsISORELA (Homo sapiens)6480464CTDaristolochic acid I inhibits the reaction [4-phenylenediamine results in increased phosphorylation of RELA protein]; TLR4 protein promotes the reaction [4-phenylenediamine results in increased phosphorylation of RELA protein]PMID:31226360
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