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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71101
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc3
Name: ATP binding cassette subfamily C member 3
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc3increases expressionEXP 6480464CTDDiethylnitrosamine results in increased expression of ABCC3 mRNAPMID:19638242 PMID:20360939
Abcc3multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ABCC3 mRNA; [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of ABCC3 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCC3 mRNAPMID:18648771 PMID:20360939 PMID:22129741
Abcc3multiple interactionsISOAbcc3 (Mus musculus)6480464CTD[Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of ABCC3 mRNAPMID:19690152
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