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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71101
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc3
Name: ATP binding cassette subfamily C member 3
Acc ID: CHEBI:34202
Term: 2,2',4,4',5,5'-hexachlorobiphenyl
Definition: A hexachlorobiphenyl that has formula C12H4Cl6.
Chemical ID: MESH:C014024
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc3increases expressionEXP 6480464CTD2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of ABCC3 mRNAPMID:20959002
Abcc3multiple interactionsEXP 6480464CTD[2,5,2',5'-tetrachlorobiphenyl co-treated with 2,2',3,5',6-pentachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3,3',4',6-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of ABCC3 mRNAPMID:29142165
Abcc3increases expressionISOAbcc3 (Mus musculus)6480464CTD2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of ABCC3 mRNAPMID:20005886
Abcc3multiple interactionsISOAbcc3 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of ABCC3 mRNAPMID:28433925
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