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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70832
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp51
Name: cytochrome P450, family 51
Acc ID: CHEBI:37187
Term: lead nitrate
Definition: A lead coordination entity that has formula N2O6Pb.
Chemical ID: MESH:C017461
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp51increases expressionEXP 6480464CTDlead nitrate results in increased expression of CYP51 mRNAPMID:22293356
Cyp51multiple interactionsEXP 6480464CTD[IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in increased expression of CYP51 mRNA]PMID:22293356
Cyp51increases expressionISOCyp51 (Rattus norvegicus)6480464CTDlead nitrate results in increased expression of CYP51 mRNAPMID:15475176
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