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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk1
Name: mitogen activated protein kinase 1
Acc ID: CHEBI:35096
Term: p-tert-Amylphenol
Definition: An alkylbenzene that has formula C11H16O.
Chemical ID: MESH:C019566
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk1decreases phosphorylationISOMAPK1 (Homo sapiens)6480464CTD4-tert-octylphenol results in decreased phosphorylation of MAPK1 proteinPMID:26133781
Mapk1multiple interactionsISOMAPK1 (Homo sapiens)6480464CTD[Diethylhexyl Phthalate co-treated with 4-tert-octylphenol] results in decreased phosphorylation of MAPK1 protein; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased phosphorylation of MAPK1 protein]PMID:26133781
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