GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | increases activity | EXP | | 6480464 | CTD | Apigenin results in increased activity of MAPK1 protein | PMID:22864849 | Mapk1 | multiple interactions | EXP | | 6480464 | CTD | Apigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] | PMID:25557508 | Mapk1 | decreases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Apigenin results in decreased phosphorylation of MAPK1 protein | PMID:27468969 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [[Apigenin results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]; [Apigenin results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK1 protein; Apigenin inhibits the reaction [TNF protein results in increased activity of MAPK1 protein]; Apigenin results in increased phosphorylation of and results in increased activity of MAPK1 protein | PMID:15322261 PMID:19647729 | | ||||||||||||||||||||||
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