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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70074
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trim3
Name: tripartite motif-containing 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trim3affects expressionISOTrim3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of TRIM3 mRNAPMID:21570461
Trim3multiple interactionsISOTRIM3 (Homo sapiens)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in decreased expression of TRIM3 mRNAPMID:29704546
Trim3multiple interactionsISOTrim3 (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of TRIM3 mRNAPMID:25975270
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