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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69325
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp11a1
Name: cytochrome P450, family 11, subfamily a, polypeptide 1
Acc ID: CHEBI:38397
Term: perfluorononanoic acid
Definition: A fluoroalkanoic acid that is nonanoic acid in which all of the hydrogens in the alkyl chain are replaced by fluorines.
Chemical ID: MESH:C101816
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp11a1decreases expressionISOCyp11a1 (Mus musculus)6480464CTDperfluoro-n-nonanoic acid results in decreased expression of CYP11A1 mRNA; perfluoro-n-nonanoic acid results in decreased expression of CYP11A1 proteinPMID:30294798
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