perfluorononanoic acid - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	perfluorononanoic acid	go back to main search page
Accession:	CHEBI:38397	browse the term
Definition:	A fluoroalkanoic acid that is nonanoic acid in which all of the hydrogens in the alkyl chain are replaced by fluorines.
Synonyms:	exact_synonym:	heptadecafluorononanoic acid
	related_synonym:	2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-heptadecafluorononanoic acid; Formula=C9HF17O2; Heptadecafluornonansaeure; Heptadekafluornonansaeure; InChI=1S/C9HF17O2/c10-2(11,1(27)28)3(12,13)4(14,15)5(16,17)6(18,19)7(20,21)8(22,23)9(24,25)26/h(H,27,28); InChIKey=UZUFPBIDKMEQEQ-UHFFFAOYSA-N; PFNA; Perfluornonansaeure; SMILES=OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F; perfluoro-n-nonanoic acid; perfluorononan-1-oic acid
	alt_id:	MESH:C584865
	xref:	CAS:375-95-1; Gmelin:317302
	xref_mesh:	MESH:C101816
	xref:	PMID:17093205; PMID:23601780; PMID:24246240; PMID:24295853; Reaxys:1897287; Wikipedia:Perfluorononanoic_acid

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Genes (1612)

perfluorononanoic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arylacetamide deacetylase-like 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of AADACL2 mRNA

NCBI chr 2:144,123,557...144,144,159

G

alanyl-tRNA synthetase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of AARS1 mRNA

NCBI chr19:55,906,694...55,930,499
Ensembl chr19:38,999,163...39,021,147

G

aminoadipate-semialdehyde synthase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AASS mRNA

NCBI chr 4:52,572,146...52,628,811
Ensembl chr 4:51,606,462...51,663,136

G

4-aminobutyrate aminotransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABAT mRNA

NCBI chr10:7,503,351...7,599,474
Ensembl chr10:6,999,819...7,092,835

G

ATP binding cassette subfamily A member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCA1 mRNA

PMID:29112762 PMID:35337807

NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily A member 12

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCA12 mRNA

NCBI chr 9:80,272,121...80,445,340
Ensembl chr 9:72,823,350...72,996,049

G

ATP binding cassette subfamily A member 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCA6 mRNA

NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530

G

ATP binding cassette subfamily A member 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCA8 mRNA

NCBI chr10:95,416,984...95,490,647
Ensembl chr10:94,917,520...94,990,988

G

ATP binding cassette subfamily B member 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCB11 mRNA

PMID:29112762 PMID:32588087

NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:54,017,127...54,112,730

G

ATP-binding cassette, sub-family B member 1B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCB1B mRNA

NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:25,242,798...25,325,199

G

ATP binding cassette subfamily B member 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCB4 mRNA

NCBI chr 4:26,106,895...26,164,440
Ensembl chr 4:25,151,953...25,209,202

G

ATP binding cassette subfamily C member 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCC2 mRNA

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCC3 mRNA

NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCC4 mRNA
perfluoro-n-nonanoic acid results in increased expression of ABCC4 mRNA

PMID:23567314 PMID:29112762 PMID:32588087

NCBI chr15:101,948,387...102,182,912
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily C member 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCC9 mRNA

NCBI chr 4:177,262,848...177,386,837
Ensembl chr 4:175,532,547...175,655,356

G

ATP binding cassette subfamily E member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCE1 mRNA

NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489

G

ATP binding cassette subfamily G member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCG1 mRNA

NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,126,687...9,182,948

G

ATP binding cassette subfamily G member 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCG2 mRNA

NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409

G

ATP binding cassette subfamily G member 5

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of ABCG5 mRNA
perfluoro-n-nonanoic acid results in decreased expression of ABCG5 mRNA

PMID:29112762 PMID:32588087

NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:9,965,118...9,990,563

G

ATP binding cassette subfamily G member 8

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of ABCG8 mRNA
perfluoro-n-nonanoic acid results in decreased expression of ABCG8 mRNA

PMID:29112762 PMID:32588087

NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:9,945,629...9,964,912

G

actin binding transcription modulator

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABITRAM mRNA

NCBI chr 5:71,505,848...71,524,224
Ensembl chr 5:71,505,813...71,511,890

G

ABL proto-oncogene 2, non-receptor tyrosine kinase

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABL2 mRNA

NCBI chr13:71,223,902...71,319,770
Ensembl chr13:68,673,722...68,839,742

G

acetyl-Coenzyme A acyltransferase 1B

increases expression

perfluoro-n-nonanoic acid results in increased expression of ACAA1B mRNA

NCBI chr 8:127,750,771...127,759,589
Ensembl chr 8:118,872,997...118,881,825

G

acetyl-CoA carboxylase beta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACACB mRNA

NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655

G

acyl-CoA dehydrogenase, long chain

increases expression

perfluoro-n-nonanoic acid results in increased expression of ACADL mRNA

NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:68,333,980...68,372,220

G

acyl-CoA dehydrogenase, short/branched chain

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACADSB mRNA

NCBI chr 1:195,619,088...195,660,564
Ensembl chr 1:186,188,987...186,230,379

G

acetyl-CoA acetyltransferase 2

multiple interactions
decreases expression

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of ACAT2 mRNA
perfluoro-n-nonanoic acid results in decreased expression of ACAT2 mRNA

PMID:32588087 PMID:33483757

NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:47,695,788...47,752,821

G

angiotensin converting enzyme 2

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of ACE2 mRNA

NCBI chr X:33,925,458...33,972,851
Ensembl chr X:30,293,589...30,340,977

G

acyl-CoA thioesterase 1

increases expression
multiple interactions
decreases expression

perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of ACOT1 mRNA
perfluoro-n-nonanoic acid results in decreased expression of ACOT1 mRNA
gadolinium chloride promotes the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]]; prolinedithiocarbamate inhibits the reaction [TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]]; TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]

PMID:22648072 PMID:28558994 PMID:32588087 PMID:33483757

NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:103,636,041...103,644,163

G

acyl-CoA thioesterase 2

multiple interactions
increases expression
decreases expression

IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]]; prolinedithiocarbamate inhibits the reaction [TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]]; TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of ACOT2 mRNA
perfluoro-n-nonanoic acid results in decreased expression of ACOT2 mRNA

PMID:22648072 PMID:28558994 PMID:32588087 PMID:33483757

NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:103,611,544...103,619,245

G

acyl-CoA oxidase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ACOX1 mRNA

PMID:23567314 PMID:25543169 PMID:28558994

NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,406,197...101,431,232

G

acyl-CoA oxidase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACOX2 mRNA

NCBI chr15:19,090,820...19,122,392
Ensembl chr15:16,660,272...16,692,160

G

acid phosphatase 5, tartrate resistant

affects expression

perfluoro-n-nonanoic acid affects the expression of ACP5 protein

NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:20,663,985...20,667,929

G

acyl-CoA synthetase family member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACSF2 mRNA

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ACSL1 mRNA

NCBI chr16:52,487,870...52,554,110
Ensembl chr16:45,755,254...45,821,541

G

acyl-CoA synthetase long-chain family member 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACSL4 mRNA

NCBI chr X:110,739,633...110,803,416
Ensembl chr X:105,942,799...106,006,427

G

acyl-CoA synthetase medium-chain family member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACSM2A mRNA

NCBI chr 1:183,347,705...183,386,453
Ensembl chr 1:173,916,368...173,955,116

G

acyl-CoA synthetase medium-chain family member 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACSM5 mRNA

NCBI chr 1:173,870,873...173,896,838
Ensembl chr 1:173,863,041...173,898,588

G

acyl-CoA synthetase short-chain family member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACSS2 mRNA

NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:144,004,336...144,059,675

G

actin, beta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACTB mRNA

NCBI chr12:16,776,664...16,779,634
Ensembl chr12:11,663,109...11,672,877

G

actin related protein 10

increases expression

perfluoro-n-nonanoic acid results in increased expression of ACTR10 mRNA

NCBI chr 6:95,182,082...95,208,325
Ensembl chr 6:89,446,093...89,473,047

G

activin A receptor like type 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACVRL1 mRNA

NCBI chr 7:134,117,917...134,135,306
Ensembl chr 7:132,239,729...132,256,591

G

adenosine deaminase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADA mRNA

NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088

G

ADAM metallopeptidase domain 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADAM7 mRNA

NCBI chr15:42,833,796...42,882,201
Ensembl chr15:42,833,796...42,882,201

G

adhesion G protein-coupled receptor E4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ADGRE4P mRNA

NCBI chr 9:10,085,258...10,240,346
Ensembl chr 9:9,760,355...9,900,760

G

adhesion G protein-coupled receptor G1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ADGRG1 mRNA

NCBI chr19:10,009,983...10,047,138
Ensembl chr19:10,003,975...10,041,108

G

adhesion G protein-coupled receptor G3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADGRG3 mRNA

NCBI chr19:9,978,450...10,007,145
Ensembl chr19:9,972,430...10,001,123

G

alcohol dehydrogenase 4 (class II), pi polypeptide

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADH4 mRNA

NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:226,947,466...226,987,591

G

alcohol dehydrogenase 6 (class V)

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADH6 mRNA

NCBI chr 2:229,576,612...229,608,359
Ensembl chr 2:226,903,250...226,934,534

G

adiponectin, C1Q and collagen domain containing

multiple interactions

[perfluorooctane sulfonic acid co-treated with perfluorooctanoic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in increased expression of ADIPOQ mRNA

NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564

G

adenosine A2a receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADORA2A mRNA

NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386

G

adenylosuccinate synthase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADSS1 mRNA

NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998

G

androgen-dependent TFPI-regulating protein

increases expression

perfluoro-n-nonanoic acid results in increased expression of ADTRP mRNA

NCBI chr17:23,113,578...23,199,616
Ensembl chr17:22,930,740...22,993,826

G

actin filament associated protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of AFAP1 mRNA

NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263

G

afamin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AFM mRNA

NCBI chr14:17,531,022...17,563,868
Ensembl chr14:17,531,024...17,563,870

G

amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AGL mRNA

NCBI chr 2:207,389,949...207,445,959
Ensembl chr 2:204,705,053...204,760,828

G

alkylglycerol monooxygenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AGMO mRNA

NCBI chr 6:59,713,495...60,044,851
Ensembl chr 6:53,986,292...54,317,623

G

1-acylglycerol-3-phosphate O-acyltransferase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AGPAT1 mRNA

NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278

G

anterior gradient 2, protein disulphide isomerase family member

increases expression

perfluoro-n-nonanoic acid results in increased expression of AGR2 mRNA

NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:52,708,602...52,729,371

G

agrin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AGRN mRNA

NCBI chr 5:172,031,528...172,064,429
Ensembl chr 5:166,749,310...166,786,003

G

alanine-glyoxylate aminotransferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AGXT2 mRNA

NCBI chr 2:61,063,416...61,104,828
Ensembl chr 2:59,336,283...59,377,926

G

AHNAK nucleoprotein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AHNAK2 mRNA

NCBI chr 6:131,830,668...131,876,311
Ensembl chr 6:131,831,454...131,854,463

G

alpha-2-HS-glycoprotein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AHSG mRNA

NCBI chr11:91,625,975...91,632,583
Ensembl chr11:78,117,918...78,145,999

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of AIMP2 mRNA

NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769

G

AT-hook transcription factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AKNA mRNA

NCBI chr 5:81,792,928...81,839,936
Ensembl chr 5:76,777,415...76,816,017

G

aldo-keto reductase family 1, member B7

multiple interactions

[PPARA gene mutant form results in increased susceptibility to perfluoro-n-nonanoic acid] which results in increased expression of AKR1B7 mRNA

NCBI chr 4:64,043,901...64,083,751
Ensembl chr 4:63,076,800...63,089,502

G

aldo-keto reductase family 1, member C1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AKR1C1 mRNA

NCBI chr17:70,720,397...70,747,285
Ensembl chr17:65,810,475...65,837,326

G

AKT serine/threonine kinase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AKT1 protein modified form

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921

G

aminolevulinate dehydratase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALAD mRNA

NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:75,961,993...75,972,474

G

5'-aminolevulinate synthase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ALAS1 mRNA

NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:106,876,514...106,889,917

G

5'-aminolevulinate synthase 2

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of ALAS2 mRNA

NCBI chr X:22,890,650...22,914,046
Ensembl chr X:19,463,171...19,486,519

G

aldehyde dehydrogenase 3 family, member A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDH3A1 mRNA

NCBI chr10:46,392,464...46,402,151
Ensembl chr10:45,892,924...45,902,681

G

aldehyde dehydrogenase 3 family, member A2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ALDH3A2 mRNA

NCBI chr10:46,427,789...46,448,449
Ensembl chr10:45,908,524...45,949,281

G

aldehyde dehydrogenase 4 family, member A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDH4A1 mRNA

NCBI chr 5:157,163,189...157,188,673
Ensembl chr 5:151,830,701...151,925,345

G

aldehyde dehydrogenase 6 family, member A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDH6A1 mRNA

NCBI chr 6:109,809,092...109,829,725
Ensembl chr 6:104,077,979...104,098,656

G

aldehyde dehydrogenase 8 family, member A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDH8A1 mRNA

NCBI chr 1:18,003,507...18,022,952
Ensembl chr 1:16,183,940...16,203,385

G

aldolase, fructose-bisphosphate B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDOB mRNA

NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:63,889,046...63,902,116

G

aldolase, fructose-bisphosphate C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDOC mRNA

NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,217,451...63,221,066

G

alkB homolog 8, tRNA methyltransferase

increases expression

perfluoro-n-nonanoic acid results in increased expression of ALKBH8 mRNA

NCBI chr 6:6,121,402...6,198,226
Ensembl chr 6:378,100...452,165

G

alpha-kinase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ALPK2 mRNA

NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258

G

alkaline phosphatase, biomineralization associated

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALPL mRNA

NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:149,951,409...150,006,446

G

alkaline phosphatase, placental

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALPP mRNA

NCBI chr 9:95,213,763...95,216,509
Ensembl chr 9:87,765,860...87,768,606

G

alpha-1-microglobulin/bikunin precursor

increases expression

perfluoro-n-nonanoic acid results in increased expression of AMBP mRNA

NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:76,568,094...76,578,331

G

amidohydrolase domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AMDHD1 mRNA

NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156

G

anti-Mullerian hormone

increases expression

perfluoro-n-nonanoic acid results in increased expression of AMH mRNA; perfluoro-n-nonanoic acid results in increased expression of AMH protein

NCBI chr 7:9,557,451...9,559,867
Ensembl chr 7:8,906,836...8,909,282

G

amphiphysin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AMPH mRNA

NCBI chr17:45,739,385...45,982,905
Ensembl chr17:45,739,395...45,983,315

G

angiogenin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANG mRNA

NCBI chr15:26,786,233...26,796,883

G

angiopoietin-like 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ANGPTL4 mRNA

PMID:23567314 PMID:32588087

NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:14,550,311...14,556,519

G

ankyrin 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ANK2 mRNA

NCBI chr 2:218,052,555...218,628,414
Ensembl chr 2:215,379,680...215,862,923

G

ankyrin and armadillo repeat containing

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANKAR mRNA

NCBI chr 9:48,141,534...48,215,400
Ensembl chr 9:48,141,391...48,215,616

G

ankyrin repeat domain 27

increases expression

perfluoro-n-nonanoic acid results in increased expression of ANKRD27 mRNA

NCBI chr 1:97,387,997...97,440,501
Ensembl chr 1:88,251,226...88,303,615

G

ankyrin repeat domain 40

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANKRD40 mRNA

NCBI chr10:79,282,075...79,295,322
Ensembl chr10:79,282,075...79,295,320
Ensembl chr10:79,282,075...79,295,320

G

ankyrin repeat domain 52

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANKRD52 mRNA

NCBI chr 7:1,390,730...1,410,139
Ensembl chr 7:806,767...820,481

G

ankyrin repeat and sterile alpha motif domain containing 1B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANKS1B mRNA

NCBI chr 7:26,200,649...27,366,552
Ensembl chr 7:24,312,843...25,477,693

G

anillin, actin binding protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANLN mRNA

NCBI chr 8:29,134,222...29,197,513
Ensembl chr 8:20,858,228...20,921,538

G

acidic nuclear phosphoprotein 32 family member E

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANP32E mRNA

NCBI chr 2:186,161,520...186,177,984
Ensembl chr 2:183,472,609...183,489,054

G

alanyl aminopeptidase, membrane

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of ANPEP mRNA

NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789

G

annexin A13

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANXA13 mRNA

NCBI chr 7:89,884,356...89,936,907
Ensembl chr 7:89,884,356...89,936,907

G

amine oxidase, copper containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AOC1 mRNA

NCBI chr 4:79,143,126...79,162,705
Ensembl chr 4:77,812,260...77,831,840

G

amine oxidase, copper containing 3

affects expression

perfluoro-n-nonanoic acid affects the expression of AOC3 protein

NCBI chr10:86,773,018...86,780,961

G

adaptor-related protein complex 1 associated regulatory protein

increases expression

perfluoro-n-nonanoic acid results in increased expression of AP1AR mRNA

NCBI chr 2:216,276,631...216,309,020
Ensembl chr 2:216,276,631...216,309,013

G

adaptor related protein complex 1 subunit gamma 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AP1G2 mRNA

NCBI chr15:32,541,528...32,549,392
Ensembl chr15:28,571,568...28,589,004

G

adaptor related protein complex 5 subunit zeta 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AP5Z1 mRNA

NCBI chr12:17,207,315...17,222,975
Ensembl chr12:12,093,834...12,108,511

G

apoptotic peptidase activating factor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of APAF1 mRNA

NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:25,494,609...25,579,540

G

aprataxin and PNKP like factor

increases expression

perfluoro-n-nonanoic acid results in increased expression of APLF mRNA

NCBI chr 4:121,627,800...121,679,980
Ensembl chr 4:120,070,471...120,122,633

G

apolipoprotein A2

increases expression

perfluoro-n-nonanoic acid results in increased expression of APOA2 mRNA

NCBI chr13:86,176,767...86,178,819
Ensembl chr13:83,644,470...83,646,355

G

apolipoprotein A4

increases expression

perfluoro-n-nonanoic acid results in increased expression of APOA4 mRNA

NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:46,539,082...46,541,469

G

apolipoprotein A5

increases expression

perfluoro-n-nonanoic acid results in increased expression of APOA5 mRNA

NCBI chr 8:55,446,329...55,460,509
Ensembl chr 8:46,561,229...46,563,816

G

apolipoprotein C1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of APOC1 mRNA

NCBI chr 1:88,475,018...88,479,052
Ensembl chr 1:79,346,136...79,350,375

G

apolipoprotein C3

decreases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of APOC3 mRNA
PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in decreased expression of APOC3 mRNA]

NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583

G

apolipoprotein E

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of APOE protein

NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932

G

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of APPL2 mRNA

NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:20,135,375...20,184,754

G

adenine phosphoribosyl transferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of APRT mRNA

NCBI chr19:67,534,737...67,537,027
Ensembl chr19:50,626,202...50,628,431

G

aquaporin 3 (Gill blood group)

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of AQP3 mRNA

NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:56,239,201...56,244,720

G

aquaporin 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AQP9 mRNA

NCBI chr 8:80,678,027...80,718,273
Ensembl chr 8:71,797,234...71,837,395

G

ARF guanine nucleotide exchange factor 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARFGEF2 mRNA

NCBI chr 3:175,966,575...176,052,715
Ensembl chr 3:155,547,538...155,630,856

G

arginase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARG1 mRNA

NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422

G

arginase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARG2 mRNA

NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:97,936,002...97,961,378

G

Rho GTPase activating protein 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARHGAP4 mRNA

NCBI chr X:156,787,566...156,802,841
Ensembl chr X:151,632,454...151,651,128

G

Rho GTPase activating protein 45

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARHGAP45 mRNA

NCBI chr 7:10,325,515...10,340,955
Ensembl chr 7:9,674,897...9,690,268

G

Rho guanine nucleotide exchange factor 19

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARHGEF19 mRNA

NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203

G

Rho/Rac guanine nucleotide exchange factor 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARHGEF2 mRNA

NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:174,062,976...174,118,355

G

Rho guanine nucleotide exchange factor 38

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARHGEF38 mRNA

NCBI chr 2:221,610,212...221,739,841
Ensembl chr 2:221,613,070...221,740,079

G

Rho guanine nucleotide exchange factor 39

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARHGEF39 mRNA

NCBI chr 5:62,548,300...62,551,870
Ensembl chr 5:57,752,509...57,756,109

G

Cdc42 guanine nucleotide exchange factor 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARHGEF9 mRNA

NCBI chr X:59,919,560...60,077,538
Ensembl chr X:59,920,870...60,077,513

G

ariadne RBR E3 ubiquitin protein ligase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARIH2 mRNA

NCBI chr 8:118,175,267...118,234,425
Ensembl chr 8:109,296,738...109,355,852

G

arkadia C-terminal like ring finger ubiquitin ligase 2C

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARK2C mRNA

NCBI chr18:70,984,566...71,100,836
Ensembl chr18:70,989,731...71,100,836

G

ARF like GTPase 16

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARL16 mRNA

NCBI chr10:105,737,455...105,739,631
Ensembl chr10:105,737,154...105,739,824

G

ARL6 interacting reticulophagy regulator 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARL6IP1 mRNA

NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:172,430,489...172,439,994

G

ARF like GTPase 8A

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARL8A mRNA

NCBI chr13:46,585,845...46,594,851
Ensembl chr13:46,585,845...46,594,851

G

cAMP-regulated phosphoprotein 19

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARPP19 mRNA

NCBI chr 8:84,660,166...84,683,012
Ensembl chr 8:75,779,523...75,802,452
Ensembl chr 8:75,779,523...75,802,452

G

arrestin domain containing 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARRDC3 mRNA

NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:11,137,460...11,149,978

G

arrestin domain containing 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARRDC4 mRNA

NCBI chr 1:131,779,436...131,793,438
Ensembl chr 1:122,369,360...122,383,290

G

ADP-ribosyltransferase 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ART4 mRNA

NCBI chr 4:169,740,331...169,751,571
Ensembl chr 4:169,740,331...169,750,665

G

ankyrin repeat and SOCS box-containing 14

increases expression

perfluoro-n-nonanoic acid results in increased expression of ASB14 mRNA

NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,095,644...2,115,135

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

perfluoro-n-nonanoic acid results in increased expression of ASNS mRNA

NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:35,785,237...35,803,423

G

assembly factor for spindle microtubules

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ASPM mRNA

NCBI chr13:53,625,584...53,674,489
Ensembl chr13:51,074,849...51,123,755

G

ATPase family, AAA domain containing 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATAD2 mRNA

NCBI chr 7:91,523,626...91,566,238
Ensembl chr 7:89,634,123...89,676,738

G

ATPase family, AAA domain containing 3A

increases expression

perfluoro-n-nonanoic acid results in increased expression of ATAD3A mRNA

NCBI chr 5:171,632,545...171,652,725
Ensembl chr 5:166,350,304...166,370,482

G

ATPase family, AAA domain containing 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATAD5 mRNA

NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,070,689...65,117,845

G

activating transcription factor 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of ATF3 mRNA

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ATF4 mRNA

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446

G

autophagy related 4A, cysteine peptidase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATG4A mRNA

NCBI chr X:104,665,345...104,765,271
Ensembl chr X:104,665,345...104,765,268

G

atonal bHLH transcription factor 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATOH8 mRNA

NCBI chr 4:105,818,203...105,850,379
Ensembl chr 4:104,259,992...104,292,168

G

ATPase Na+/K+ transporting subunit alpha 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATP1A1 mRNA

NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:189,020,722...189,048,837

G

ATPase Na+/K+ transporting subunit alpha 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATP1A2 mRNA

NCBI chr13:87,261,964...87,286,911
Ensembl chr13:84,729,601...84,754,544

G

ATPase plasma membrane Ca2+ transporting 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ATP2B1 mRNA

NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:33,735,871...33,843,295

G

ATPase plasma membrane Ca2+ transporting 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATP2B2 mRNA

NCBI chr 4:148,450,207...148,763,653
Ensembl chr 4:146,896,332...147,140,665

G

ATPase plasma membrane Ca2+ transporting 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ATP2B4 mRNA

NCBI chr13:47,708,157...47,807,389
Ensembl chr13:45,156,146...45,255,246

G

ATP synthase inhibitory factor subunit 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATP5IF1 mRNA

NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:144,738,950...144,742,668

G

ATPase, H+ transporting V0 subunit e2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATP6V0E2 mRNA

NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777

G

ataxin 2-like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATXN2L mRNA

NCBI chr 1:181,078,293...181,090,079
Ensembl chr 1:181,078,288...181,089,686

G

aurora kinase A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AURKA mRNA

NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:161,128,313...161,144,390

G

aurora kinase B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AURKB mRNA

NCBI chr10:54,243,116...54,249,675
Ensembl chr10:53,745,142...53,750,837

G

axin 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of AXIN1 mRNA

NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,163,684...15,215,615

G

beta-1,4-galactosyltransferase 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of B4GALT5 mRNA

NCBI chr 3:176,437,073...176,453,001
Ensembl chr 3:156,018,053...156,070,074

G

bile acid CoA:amino acid N-acyltransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BAAT mRNA

NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:63,850,705...63,860,685

G

BAR/IMD domain containing adaptor protein 2 like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of BAIAP2L1 mRNA

NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928

G

BAI1-associated protein 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BAIAP3 mRNA

NCBI chr10:14,764,768...14,777,516
Ensembl chr10:14,260,269...14,273,019

G

BCL2 associated X, apoptosis regulator

increases expression

perfluoro-n-nonanoic acid results in increased expression of BAX mRNA

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368

G

butyrylcholinesterase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BCHE mRNA

NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:158,307,584...158,401,148

G

BCL2, apoptosis regulator

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of BCL2 mRNA; perfluoro-n-nonanoic acid results in decreased expression of BCL2 protein
perfluoro-n-nonanoic acid results in increased expression of BCL2 mRNA

PMID:19196829 PMID:19646514 PMID:19878704 PMID:32588087

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

BCL9 like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BCL9L mRNA

NCBI chr 8:53,708,770...53,738,880
Ensembl chr 8:44,811,977...44,840,611

G

BCLAF1 and THRAP3 family member 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BCLAF3 mRNA

NCBI chr X:39,065,842...39,137,521
Ensembl chr X:35,263,576...35,328,816

G

3-hydroxybutyrate dehydrogenase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BDH1 mRNA

NCBI chr11:82,806,125...82,848,133
Ensembl chr11:69,302,534...69,337,671

G

brain-derived neurotrophic factor

multiple interactions

[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluoro-n-nonanoic acid] which results in decreased expression of BDNF protein

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615

G

baculoviral IAP repeat-containing 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of BIRC3 mRNA

NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BIRC5 mRNA

NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380

G

biogenesis of lysosomal organelles complex-1, subunit 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of BLOC1S2 mRNA

NCBI chr 1:252,973,818...252,980,873
Ensembl chr 1:243,024,614...243,031,653

G

bridge-like lipid transfer protein family member 3A

increases expression

perfluoro-n-nonanoic acid results in increased expression of BLTP3A mRNA

NCBI chr20:5,910,261...5,954,641
Ensembl chr20:5,910,260...5,952,404

G

bone morphogenetic protein 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BMP4 mRNA

NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306

G

basonuclin zinc finger protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of BNC1 mRNA

NCBI chr 1:145,326,881...145,352,534
Ensembl chr 1:135,917,687...135,943,333

G

BCL2 interacting protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of BNIP3 mRNA

NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359

G

biorientation of chromosomes in cell division 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of BOD1 mRNA

NCBI chr10:16,497,918...16,504,259
Ensembl chr10:15,993,454...15,999,787

G

bora, aurora kinase A activator

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BORA mRNA

NCBI chr15:82,205,467...82,243,499
Ensembl chr15:75,797,891...75,821,322

G

biphenyl hydrolase like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BPHL mRNA

NCBI chr17:30,800,939...30,837,277
Ensembl chr17:30,799,629...30,837,288

G

BRF2 general transcription factor 3B subunit

increases expression

perfluoro-n-nonanoic acid results in increased expression of BRF2 mRNA

NCBI chr16:64,928,334...64,933,057
Ensembl chr16:64,928,300...64,933,059

G

BMP/retinoic acid inducible neural specific 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BRINP1 mRNA

NCBI chr 5:87,363,621...87,565,580
Ensembl chr 5:82,348,930...82,493,150

G

BMP/retinoic acid inducible neural specific 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BRINP3 mRNA

NCBI chr13:60,964,127...61,397,044
Ensembl chr13:58,413,883...58,846,770

G

bromodomain and PHD finger containing, 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BRPF1 mRNA

NCBI chr 4:146,456,325...146,472,781
Ensembl chr 4:146,456,318...146,472,649

G

BUB1 mitotic checkpoint serine/threonine kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BUB1 mRNA

NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:115,020,254...115,051,650

G

bystin-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of BYSL mRNA

NCBI chr 9:20,880,341...20,890,092
Ensembl chr 9:13,382,557...13,394,339

G

similar to human chromosome 1 open reading frame 226

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C1ORF226 mRNA

NCBI chr13:82,530,589...82,538,676
Ensembl chr13:82,530,577...82,820,949

G

C1q and TNF related 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C1QTNF1 mRNA

NCBI chr10:104,159,021...104,180,253
Ensembl chr10:103,660,327...103,681,660

G

C1q and TNF related 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C1QTNF6 mRNA

NCBI chr 7:111,958,348...111,964,948
Ensembl chr 7:110,077,878...110,084,412

G

complement C3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C3 mRNA

NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429

G

complement component 4 binding protein, beta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C4BPB mRNA

NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817

G

complement C8 alpha chain

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C8A mRNA

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

G

similar to human chromosome 11 open reading frame 54

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C11ORF54 mRNA

NCBI chr 8:20,405,240...20,427,811
Ensembl chr 8:12,123,823...12,146,473

G

similar to human chromosome 3 open reading frame 18

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C3ORF18 mRNA

NCBI chr 8:108,012,638...108,022,050
Ensembl chr 8:108,012,638...108,022,461

G

complement C9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C9 mRNA

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

G

similar to human chromosome 2 open reading frame 72

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C2ORF72 mRNA

NCBI chr 9:86,691,767...86,699,920
Ensembl chr 9:86,691,867...86,698,185

G

colon adenocarcinoma hypermethylated

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CAHM mRNA

NCBI chr 1:50,385,803...50,386,959

G

calcitonin receptor like receptor

increases expression

perfluoro-n-nonanoic acid results in increased expression of CALCRL mRNA

NCBI chr 3:89,835,071...89,932,616
Ensembl chr 3:69,430,120...69,525,910

G

calmodulin-like 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CALML4 mRNA

NCBI chr 8:63,323,426...63,335,234
Ensembl chr 8:63,323,351...63,335,234

G

calmodulin regulated spectrin-associated protein family, member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CAMSAP2 mRNA

NCBI chr13:47,723,251...47,802,606
Ensembl chr13:47,723,121...47,802,597

G

calpain 10

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CAPN10 mRNA

NCBI chr 9:93,498,132...93,510,494
Ensembl chr 9:93,498,478...93,510,494

G

calpain 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of CAPN5 mRNA

NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923

G

carbonic anhydrase 9

increases expression

perfluoro-n-nonanoic acid results in increased expression of CA9 mRNA

NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:57,763,206...57,769,838

G

caspase recruitment domain family, member 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CARD11 mRNA

NCBI chr12:18,735,088...18,872,045
Ensembl chr12:13,621,087...13,758,112

G

caspase recruitment domain family, member 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CARD6 mRNA

NCBI chr 2:54,194,343...54,206,902
Ensembl chr 2:54,195,739...54,206,846

G

cysteinyl-tRNA synthetase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CARS1 mRNA

NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:198,753,691...198,795,941

G

caspase 14

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CASP14 mRNA

NCBI chr 7:11,577,315...11,583,987
Ensembl chr 7:10,926,725...10,933,405

G

caspase 3

decreases expression
decreases cleavage

perfluoro-n-nonanoic acid results in decreased expression of CASP3 protein
perfluoro-n-nonanoic acid results in decreased cleavage of CASP3 protein

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

decreases expression
increases activity

perfluoro-n-nonanoic acid results in decreased expression of CASP8 protein
perfluoro-n-nonanoic acid results in increased activity of CASP8 protein

PMID:19646514 PMID:19878704

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542

G

cation channel sperm associated auxiliary subunit gamma

increases expression

perfluoro-n-nonanoic acid results in increased expression of CATSPERG mRNA

NCBI chr 1:84,488,728...84,519,495
Ensembl chr 1:84,488,730...84,519,559

G

caveolae associated protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CAVIN1 mRNA

NCBI chr10:86,384,401...86,398,240
Ensembl chr10:85,889,036...85,896,120

G

caveolae associated protein 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CAVIN3 mRNA

NCBI chr 1:169,238,384...169,239,973
Ensembl chr 1:159,826,549...159,828,161

G

Cbl proto-oncogene B

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of CBLB mRNA
perfluoro-n-nonanoic acid results in decreased expression of CBLB mRNA

PMID:25812627 PMID:32588087

NCBI chr11:62,058,829...62,225,904
Ensembl chr11:48,592,703...48,756,839

G

chromobox 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of CBX4 mRNA

NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706

G

cell cycle and apoptosis regulator 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCAR2 mRNA

NCBI chr15:51,622,519...51,637,911
Ensembl chr15:45,212,803...45,227,636

G

coiled-coil domain containing 107

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCDC107 mRNA

NCBI chr 5:62,545,273...62,548,711
Ensembl chr 5:57,748,999...57,752,918

G

coiled-coil domain containing 178

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCDC178 mRNA

NCBI chr18:13,074,834...13,472,732
Ensembl chr18:13,075,468...13,472,160

G

coiled-coil domain containing 59

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCDC59 mRNA

NCBI chr 7:41,142,760...41,149,143
Ensembl chr 7:41,142,760...41,149,143

G

coiled-coil domain containing 69

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCDC69 mRNA

NCBI chr10:39,173,282...39,200,358
Ensembl chr10:39,173,282...39,199,878

G

coiled-coil domain containing 85C

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCDC85C mRNA

NCBI chr 6:127,113,440...127,184,328
Ensembl chr 6:127,113,442...127,184,371

G

C-C motif chemokine ligand 20

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of CCL20 mRNA
perfluoro-n-nonanoic acid results in decreased expression of CCL20 mRNA

PMID:32588087 PMID:38568856

NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:84,388,904...84,391,629

G

cellular communication network factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCN1 mRNA

NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:234,562,408...234,565,484

G

cellular communication network factor 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCN2 mRNA

NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734

G

cellular communication network factor 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of WISP1 mRNA

NCBI chr 7:100,534,578...100,566,287
Ensembl chr 7:98,645,182...98,677,248

G

cyclin A2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCNA2 mRNA

NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCNB1 mRNA

NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172

G

cyclin D1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCND1 mRNA

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCND2 mRNA

NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:159,962,363...159,989,495

G

cyclin F

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCNF mRNA

NCBI chr10:13,757,884...13,783,669
Ensembl chr10:13,253,380...13,279,101

G

cell cycle progression 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCPG1 mRNA

NCBI chr 8:82,600,677...82,633,082
Ensembl chr 8:73,719,955...73,752,430

G

CD14 molecule

increases expression

perfluoro-n-nonanoic acid results in increased expression of CD14 mRNA

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261

G

Cd200 molecule

increases expression

perfluoro-n-nonanoic acid results in increased expression of CD200 mRNA

NCBI chr11:68,916,200...68,943,570
Ensembl chr11:55,410,196...55,501,648

G

CD22 molecule

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CD22 mRNA

NCBI chr 1:95,243,785...95,270,430
Ensembl chr 1:86,117,459...86,132,322

G

CD24 molecule

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CD24 mRNA

NCBI chr20:48,655,549...48,661,786
Ensembl chr20:47,073,512...47,079,662

G

CD36 molecule

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of CD36 mRNA
PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CD36 mRNA]

NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903

G

CD3 epsilon subunit of T-cell receptor complex

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CD3E mRNA

NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:45,303,852...45,315,022

G

CD40 molecule

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CD40 protein

NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534

G

cell division cycle 20

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDC20 mRNA

NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:131,966,215...131,970,512

G

cell division cycle 20B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDC20B mRNA

NCBI chr 2:44,688,349...44,738,056

G

cell division cycle 25C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDC25C mRNA

NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,335,834...26,356,185

G

cell division cycle 37-like 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDC37L1 mRNA

NCBI chr 1:226,705,019...226,733,994
Ensembl chr 1:226,705,003...226,761,175

G

CDC42 binding protein kinase beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of CDC42BPB mRNA

NCBI chr 6:130,333,712...130,416,631
Ensembl chr 6:130,333,712...130,416,377

G

CDC42 effector protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CDC42EP1 mRNA

NCBI chr 7:112,275,759...112,283,665
Ensembl chr 7:110,395,332...110,403,200

G

cell division cycle associated 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDCA3 mRNA

NCBI chr 4:159,321,203...159,325,072
Ensembl chr 4:157,634,928...157,638,799

G

cadherin 13

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDH13 mRNA

NCBI chr19:63,258,251...64,296,122
Ensembl chr19:46,349,430...47,387,459

G

cyclin-dependent kinase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDK1 mRNA

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,266,248...19,281,408

G

cyclin dependent kinase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDK2 mRNA

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 2 associated protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDK2AP2 mRNA

NCBI chr 1:210,819,155...210,822,604
Ensembl chr 1:201,391,466...201,393,137

G

cyclin-dependent kinase inhibitor 2C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDKN2C mRNA

PMID:25812627 PMID:32588087

NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:124,411,124...124,416,278

G

cyclin dependent kinase inhibitor 2D

increases expression

perfluoro-n-nonanoic acid results in increased expression of CDKN2D mRNA

NCBI chr 8:28,108,036...28,110,809
Ensembl chr 8:19,831,866...19,834,674

G

CCAAT/enhancer binding protein gamma

increases expression

perfluoro-n-nonanoic acid results in increased expression of CEBPG mRNA

NCBI chr 1:96,820,981...96,829,736
Ensembl chr 1:87,684,019...87,694,569

G

carboxyl ester lipase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CEL mRNA

NCBI chr 3:32,281,518...32,289,019
Ensembl chr 3:11,883,532...11,891,035

G

centromere protein A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CENPA mRNA

NCBI chr 6:31,420,062...31,431,703
Ensembl chr 6:25,700,142...25,711,675

G

centromere protein E

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CENPE mRNA

NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:223,636,998...223,695,669

G

centromere protein I

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CENPI mRNA

NCBI chr X:101,809,192...101,860,935
Ensembl chr X:97,515,972...97,567,657

G

centrosomal protein 131

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CEP131 mRNA

NCBI chr10:105,844,433...105,868,811
Ensembl chr10:105,346,015...105,370,380

G

centrosomal protein 152

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CEP152 mRNA

NCBI chr 3:133,243,979...133,332,271
Ensembl chr 3:112,810,425...112,878,458
Ensembl chr 3:112,810,425...112,878,458

G

centrosomal protein 290

increases expression

perfluoro-n-nonanoic acid results in increased expression of CEP290 mRNA

NCBI chr 7:37,196,765...37,285,955
Ensembl chr 7:35,310,199...35,399,392

G

centrosomal protein 78

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CEP78 mRNA

PMID:25812627 PMID:32588087

NCBI chr 1:213,246,183...213,275,275
Ensembl chr 1:213,246,187...213,275,181

G

ceramide synthase 6

increases expression

perfluoro-n-nonanoic acid results in increased expression of CERS6 mRNA

NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848

G

carboxylesterase 2C

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CES2C mRNA

NCBI chr 1:270,377,201...270,384,768
Ensembl chr 1:260,388,902...260,398,790

G

centrin 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CETN2 mRNA

NCBI chr X:155,812,212...155,817,186
Ensembl chr X:150,769,953...150,774,919

G

cilia and flagella associated protein 263

increases expression

perfluoro-n-nonanoic acid results in increased expression of CFAP263 mRNA

NCBI chr19:9,503,062...9,522,957
Ensembl chr19:9,496,886...9,516,923

G

cilia and flagella associated protein 68

increases expression

perfluoro-n-nonanoic acid results in increased expression of CFAP68 mRNA

NCBI chr 8:51,107,663...51,113,192
Ensembl chr 8:51,107,721...51,113,420

G

cilia and flagella associated protein 97

increases expression

perfluoro-n-nonanoic acid results in increased expression of CFAP97 mRNA

NCBI chr16:46,086,104...46,135,194
Ensembl chr16:46,086,111...46,125,933

G

complement factor H-related 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CFHR4 mRNA

NCBI chr13:53,973,301...54,042,179
Ensembl chr13:51,422,592...51,491,502

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CHAC1 mRNA

NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:106,342,302...106,345,526

G

coiled-coil-helix-coiled-coil-helix domain containing 10

increases expression

perfluoro-n-nonanoic acid results in increased expression of CHCHD10 mRNA

NCBI chr20:12,725,274...12,730,295
Ensembl chr20:12,725,842...12,732,763

G

charged multivesicular body protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of CHMP3 mRNA

NCBI chr 4:105,134,860...105,180,862
Ensembl chr 4:103,576,515...103,623,959

G

chimerin 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CHN2 mRNA

NCBI chr 4:84,478,989...84,738,068
Ensembl chr 4:83,147,983...83,407,709

G

carbohydrate sulfotransferase 11

increases expression

perfluoro-n-nonanoic acid results in increased expression of CHST11 mRNA

NCBI chr 7:22,412,121...22,630,577
Ensembl chr 7:20,528,100...20,743,111

G

carbohydrate sulfotransferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CHST2 mRNA

NCBI chr 8:95,960,067...95,966,312
Ensembl chr 8:95,959,826...95,966,955

G

carbohydrate sulfotransferase 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CHST9 mRNA

NCBI chr18:6,850,874...7,125,222
Ensembl chr18:6,577,348...6,850,868

G

cell death-inducing DFFA-like effector a

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of CIDEA mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CIDEA mRNA

PMID:25812627 PMID:33483757

NCBI chr18:63,164,817...63,190,384
Ensembl chr18:60,894,874...60,920,481

G

cell death-inducing DFFA-like effector b

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CIDEB mRNA

NCBI chr15:33,222,135...33,226,407
Ensembl chr15:29,252,213...29,256,605

G

cell death-inducing DFFA-like effector c

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of CIDEC mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CIDEC mRNA; PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CIDEC mRNA]

PMID:28049043 PMID:33483757

NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:146,569,289...146,582,173

G

class II, major histocompatibility complex, transactivator

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CIITA mRNA

NCBI chr10:5,646,854...5,694,393
Ensembl chr10:5,140,178...5,187,440

G

CDC28 protein kinase regulatory subunit 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CKS2 mRNA

NCBI chr17:13,722,360...13,727,519

G

CLK4-associating serine/arginine rich protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLASRP mRNA

NCBI chr 1:79,232,260...79,256,462
Ensembl chr 1:79,232,261...79,256,354

G

claudin 14

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLDN14 mRNA

NCBI chr11:46,701,940...46,799,049
Ensembl chr11:33,232,220...33,329,171

G

claudin 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLDN8 mRNA

NCBI chr11:41,362,081...41,364,330
Ensembl chr11:27,875,692...27,878,513

G

C-type lectin domain family 1, member A

affects expression

perfluoro-n-nonanoic acid affects the expression of CLEC1A protein

NCBI chr 4:162,875,360...162,902,571
Ensembl chr 4:162,877,346...162,901,247

G

calmegin

increases expression

perfluoro-n-nonanoic acid results in increased expression of CLGN mRNA

NCBI chr19:41,601,568...41,633,207
Ensembl chr19:24,696,875...24,728,758

G

CAP-GLY domain containing linker protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CLIP1 mRNA

NCBI chr12:38,571,533...38,678,779
Ensembl chr12:32,910,977...33,017,884

G

CAP-GLY domain containing linker protein family, member 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of CLIP4 mRNA

NCBI chr 6:23,616,280...23,697,625
NCBI chr 6:23,718,580...23,729,231
NCBI chr 6:23,597,729...23,601,000
Ensembl chr 6:23,616,281...23,677,874

G

clarin 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLRN3 mRNA

NCBI chr 1:190,319,025...190,334,648
Ensembl chr 1:190,319,026...190,334,648

G

claspin

increases expression

perfluoro-n-nonanoic acid results in increased expression of CLSPN mRNA

NCBI chr 5:144,134,619...144,169,531
Ensembl chr 5:138,850,128...138,885,034

G

clustered mitochondria homolog

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLUH mRNA

PMID:25812627 PMID:38568856

NCBI chr10:59,509,580...59,531,345
Ensembl chr10:59,509,726...59,531,345

G

citramalyl-CoA lyase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLYBL mRNA

NCBI chr15:105,690,283...105,912,347
Ensembl chr15:99,283,650...99,505,695

G

chemerin chemokine-like receptor 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CMKLR2 mRNA

NCBI chr 9:72,077,164...72,111,979
Ensembl chr 9:64,585,594...64,586,655

G

cms1 ribosomal small subunit homolog

increases expression

perfluoro-n-nonanoic acid results in increased expression of CMSS1 mRNA

NCBI chr11:42,934,390...43,232,624
Ensembl chr11:42,934,440...43,232,624

G

CKLF-like MARVEL transmembrane domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CMTM1 mRNA

NCBI chr19:651,641...661,184
Ensembl chr19:651,644...661,184

G

cyclic nucleotide binding domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CNBD1 mRNA

NCBI chr 5:32,234,003...32,606,765
Ensembl chr 5:32,329,368...32,606,705

G

connector enhancer of kinase suppressor of Ras 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CNKSR2 mRNA

NCBI chr X:36,908,135...37,148,337
Ensembl chr X:36,907,850...37,150,555

G

2',3'-cyclic nucleotide 3' phosphodiesterase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CNP mRNA

NCBI chr10:86,011,504...86,018,063
Ensembl chr10:85,511,160...85,517,720

G

collagen type XIV alpha 1 chain

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of COL14A1 mRNA

NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:86,722,094...86,937,214

G

coenzyme Q10A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of COQ10A mRNA

NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161

G

cytochrome c oxidase assembly factor COX19

increases expression

perfluoro-n-nonanoic acid results in increased expression of COX19 mRNA

NCBI chr12:20,417,389...20,426,868
Ensembl chr12:15,303,551...15,313,014

G

cytoplasmic polyadenylation element binding protein 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of CPEB4 mRNA

NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603

G

cadherin-like and PC-esterase domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CPED1 mRNA

NCBI chr 4:50,516,712...50,789,651
Ensembl chr 4:50,516,819...50,788,674

G

carboxypeptidase M

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CPM mRNA

NCBI chr 7:55,111,599...55,172,114
Ensembl chr 7:53,225,696...53,286,220

G

carboxypeptidase N subunit 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CPN1 mRNA

NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465

G

carbamoyl-phosphate synthase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CPS1 mRNA

NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:68,614,153...68,737,033

G

carnitine palmitoyltransferase 1A

multiple interactions
decreases expression
increases expression

gadolinium chloride promotes the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]]; prolinedithiocarbamate inhibits the reaction [TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]]; TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]
perfluoro-n-nonanoic acid results in decreased expression of CPT1A mRNA

PMID:22648072 PMID:23567314 PMID:32588087 PMID:38568856

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 1B

affects expression
increases expression
multiple interactions

perfluoro-n-nonanoic acid affects the expression of CPT1B mRNA
perfluoro-n-nonanoic acid results in increased expression of CPT1B mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CPT1B mRNA

PMID:23567314 PMID:33483757 PMID:35337807

NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:120,491,354...120,500,404

G

carnitine palmitoyltransferase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CPT2 mRNA

NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095

G

carboxypeptidase Z

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CPZ mRNA

NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945

G

carnitine O-acetyltransferase

increases expression

perfluoro-n-nonanoic acid results in increased expression of CRAT mRNA

NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:13,675,684...13,689,255

G

cAMP responsive element binding protein 3-like 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of CREB3L3 mRNA

PMID:28558994 PMID:32588087

NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048

G

CREB3 regulatory factor

increases expression

perfluoro-n-nonanoic acid results in increased expression of CREBRF mRNA

NCBI chr10:16,903,607...16,967,450
Ensembl chr10:16,404,596...16,461,999

G

cysteine-rich with EGF-like domains 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CRELD2 mRNA

NCBI chr 7:121,788,754...121,796,230
Ensembl chr 7:119,909,633...119,916,543

G

carnitine O-octanoyltransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CROT mRNA

NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:25,080,587...25,133,109

G

C-reactive protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CRP mRNA

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178

G

CREB regulated transcription coactivator 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CRTC3 mRNA

NCBI chr 1:143,962,038...144,064,324
Ensembl chr 1:134,554,696...134,655,500

G

crystallin, beta A1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CRYBA1 mRNA

NCBI chr10:62,608,373...62,614,726
Ensembl chr10:62,608,383...62,614,726

G

crystallin, mu

increases expression

perfluoro-n-nonanoic acid results in increased expression of CRYM mRNA

NCBI chr 1:183,991,752...184,006,923
Ensembl chr 1:174,560,416...174,575,633

G

colony stimulating factor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CSF1 protein

NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:195,377,215...195,411,704

G

cysteine and serine rich nuclear protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CSRNP2 mRNA

NCBI chr 7:131,594,232...131,610,075
Ensembl chr 7:131,594,232...131,610,075

G

cysteine and glycine rich protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of CSRP3 mRNA

NCBI chr 1:107,664,338...107,682,916
Ensembl chr 1:98,528,068...98,546,653

G

cystatin A

increases expression

perfluoro-n-nonanoic acid results in increased expression of CSTA mRNA

NCBI chr11:78,125,813...78,136,818
Ensembl chr11:64,620,483...64,631,488

G

cystatin B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CSTB protein

NCBI chr20:10,245,157...10,247,199
Ensembl chr20:10,245,462...10,247,526

G

cystatin-like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CSTL1 mRNA

NCBI chr 3:136,199,914...136,204,912
Ensembl chr 3:136,199,914...136,204,912

G

C-terminal binding protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CTBP1 mRNA

NCBI chr14:81,679,956...81,707,331
Ensembl chr14:77,455,696...77,482,821

G

cystathionine gamma-lyase

increases expression

perfluoro-n-nonanoic acid results in increased expression of CTH mRNA

NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:246,975,894...247,002,234

G

cap binding complex dependent translation initiation factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CTIF mRNA

NCBI chr18:69,056,151...69,327,454
Ensembl chr18:69,059,519...69,327,385

G

CTP synthase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CTPS2 mRNA

NCBI chr X:35,277,658...35,418,505
Ensembl chr X:31,645,873...31,786,733

G

cathepsin W

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CTSW mRNA

NCBI chr 1:212,201,904...212,208,028
Ensembl chr 1:202,772,572...202,775,964

G

C-X-C motif chemokine ligand 10

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CXCL10 mRNA

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 16

increases expression

perfluoro-n-nonanoic acid results in increased expression of CXCL16 mRNA

NCBI chr10:55,665,355...55,669,950
Ensembl chr10:55,166,723...55,171,592

G

CXXC finger protein 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CXXC5 mRNA

NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673

G

cytochrome b561 family, member A3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYB561A3 mRNA

NCBI chr 1:207,216,185...207,237,575
Ensembl chr 1:207,226,230...207,237,571

G

cytochrome b5 type B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYB5B mRNA

NCBI chr19:51,972,611...52,006,477
Ensembl chr19:35,062,813...35,098,249

G

cytoglobin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYGB mRNA

NCBI chr10:102,376,506...102,386,272
Ensembl chr10:101,877,676...101,887,442

G

cytochrome P450, family 11, subfamily a, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP11A1 mRNA; perfluoro-n-nonanoic acid results in decreased expression of CYP11A1 protein

NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CYP17A1 mRNA

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

multiple interactions

[perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of CYP19A1 mRNA

NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP1A1 mRNA

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP1B1 mRNA

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 27, subfamily a, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP27A1 mRNA

PMID:29112762 PMID:32588087

NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 2, subfamily b, polypeptide 3

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of CYP2B6 mRNA
perfluoro-n-nonanoic acid results in increased expression of CYP2B10 mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CYP2B10 mRNA; [PPARA gene mutant form results in increased susceptibility to perfluoro-n-nonanoic acid] which results in increased expression of CYP2B10 mRNA

PMID:23567314 PMID:25543169 PMID:25949234 PMID:28558994 PMID:33483757

NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily c, polypeptide 24

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of CYP2C55 mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CYP2C55 mRNA

PMID:28558994 PMID:33483757

NCBI chr 1:246,286,341...246,348,607
Ensembl chr 1:236,873,967...236,936,238

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP2E1 mRNA

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 39, subfamily a, polypeptide 1

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of CYP39A1 mRNA

NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:17,230,455...17,306,775

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CYP3A4 mRNA

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 4, subfamily x, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP4X1 mRNA

NCBI chr 5:128,651,681...128,683,338
Ensembl chr 5:128,651,776...128,682,779

G

cytochrome P450 family 7 subfamily A member 1

decreases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of CYP7A1 mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of CYP7A1 mRNA

PMID:23567314 PMID:29112762 PMID:32588087 PMID:33483757

NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688

G

cytochrome P450 family 7 subfamily B member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP7B1 mRNA

NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:100,502,791...100,669,698

G

cytochrome P450 family 8 subfamily B member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP8B1 mRNA

PMID:29112762 PMID:32588087

NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:121,557,062...121,580,166

G

cytokine like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CYTL1 mRNA

NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886

G

DAB adaptor protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DAB1 mRNA

NCBI chr 5:123,621,510...124,742,585
Ensembl chr 5:119,140,533...119,510,552

G

D-amino-acid oxidase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DAO mRNA

NCBI chr12:48,252,900...48,275,964
Ensembl chr12:42,592,343...42,612,741

G

aspartyl-tRNA synthetase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DARS1 mRNA

NCBI chr13:39,857,936...39,913,055
Ensembl chr13:39,857,936...39,913,116

G

diazepam binding inhibitor

increases expression

perfluoro-n-nonanoic acid results in increased expression of DBI mRNA

NCBI chr13:33,794,231...33,802,632
Ensembl chr13:31,206,988...31,268,693

G

drebrin 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DBN1 mRNA

NCBI chr17:9,155,729...9,170,121
Ensembl chr17:9,150,659...9,164,984

G

D-box binding PAR bZIP transcription factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DBP mRNA

NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:96,175,440...96,180,745

G

DDB1 and CUL4 associated factor 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DCAF11 mRNA

NCBI chr15:33,015,370...33,027,407
Ensembl chr15:29,046,826...29,057,669

G

discoidin, CUB and LCCL domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DCBLD1 mRNA

NCBI chr20:31,618,556...31,711,697
Ensembl chr20:31,618,542...31,711,692

G

dachsous cadherin-related 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DCHS1 mRNA

NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808

G

deoxycytidine kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DCK mRNA

NCBI chr14:19,589,298...19,610,326
Ensembl chr14:19,305,218...19,326,247

G

doublecortin-like kinase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DCLK1 mRNA

NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:139,417,163...139,710,956

G

dicarbonyl and L-xylulose reductase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DCXR mRNA

NCBI chr10:106,504,730...106,506,619

G

DNA-damage inducible transcript 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of DDIT3 mRNA

PMID:23567314 PMID:32588087

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of DDIT4 mRNA

NCBI chr20:28,434,938...28,437,037
Ensembl chr20:27,891,998...27,894,105

G

DEAD/H-box helicase 11

increases expression

perfluoro-n-nonanoic acid results in increased expression of DDX11 mRNA

NCBI chr 9:113,204,886...113,309,692
Ensembl chr 9:105,833,504...105,862,550

G

DExD-box helicase 21

increases expression

perfluoro-n-nonanoic acid results in increased expression of DDX21 mRNA

NCBI chr20:31,077,044...31,097,238
Ensembl chr20:30,534,319...30,554,543

G

DExD-box helicase 50

increases expression

perfluoro-n-nonanoic acid results in increased expression of DDX50 mRNA

NCBI chr20:31,104,354...31,133,652
Ensembl chr20:30,560,544...30,591,152

G

DEAD-box helicase 54

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DDX54 mRNA

NCBI chr12:41,595,298...41,610,560
Ensembl chr12:35,934,716...35,972,523

G

2,4-dienoyl-CoA reductase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DECR1 mRNA

NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018

G

DENN domain containing 1C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DENND1C mRNA

NCBI chr 9:1,904,040...1,916,329
Ensembl chr 9:1,904,045...1,916,187

G

DEP domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DEPDC1 mRNA

NCBI chr 2:251,343,250...251,376,709
Ensembl chr 2:248,684,523...248,717,951

G

DEP domain containing 1B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DEPDC1B mRNA

NCBI chr 2:41,605,686...41,697,207
Ensembl chr 2:39,891,481...39,963,779

G

DEP domain containing 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DEPDC7 mRNA

NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124

G

desumoylating isopeptidase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DESI1 mRNA

NCBI chr 7:115,401,613...115,422,974
Ensembl chr 7:113,519,980...113,542,845

G

diacylglycerol O-acyltransferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DGAT2 mRNA

NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:153,454,080...153,484,428

G

DiGeorge syndrome critical region gene 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DGCR6 mRNA

NCBI chr11:82,927,725...82,932,823
Ensembl chr11:82,927,725...82,932,823

G

diacylglycerol kinase, beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of DGKB mRNA

NCBI chr 6:60,368,101...61,124,420
Ensembl chr 6:54,641,614...55,397,043

G

diacylglycerol kinase, eta

increases expression

perfluoro-n-nonanoic acid results in increased expression of DGKH mRNA

NCBI chr15:60,390,279...60,559,777
Ensembl chr15:53,991,481...54,150,706

G

D-glutamate cyclase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DGLUCY mRNA

NCBI chr 6:125,785,075...125,860,496
Ensembl chr 6:120,055,460...120,130,910

G

7-dehydrocholesterol reductase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DHCR7 mRNA

NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:199,015,081...199,031,055

G

dihydroorotate dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DHODH mRNA

NCBI chr19:54,460,636...54,483,049
Ensembl chr19:37,558,177...37,591,654

G

dehydrogenase/reductase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DHRS1 mRNA

NCBI chr15:33,206,449...33,213,776
Ensembl chr15:29,236,522...29,243,838

G

dehydrogenase/reductase 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of DHRS4 mRNA

NCBI chr15:32,924,482...32,948,103
Ensembl chr15:28,966,553...28,978,127

G

dehydrogenase E1 and transketolase domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DHTKD1 mRNA

NCBI chr17:77,242,512...77,316,074
Ensembl chr17:72,355,201...72,406,723

G

iodothyronine deiodinase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DIO1 mRNA

NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:122,074,279...122,090,970

G

dyskerin pseudouridine synthase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DKC1 mRNA

NCBI chr X:157,751,651...157,757,796

G

dickkopf WNT signaling pathway inhibitor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DKK1 mRNA; perfluoro-n-nonanoic acid results in decreased expression of DKK1 protein

PMID:32588087 PMID:32916415

NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:228,381,521...228,385,202

G

discs large MAGUK scaffold protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of DLG2 mRNA

NCBI chr 1:153,864,545...155,916,238
Ensembl chr 1:144,451,472...146,499,475

G

discs large MAGUK scaffold protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of DLG3 mRNA

NCBI chr X:69,899,694...69,951,928
Ensembl chr X:65,860,172...65,910,322

G

dimethylglycine dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DMGDH mRNA

NCBI chr 2:26,647,540...26,722,496
Ensembl chr 2:24,912,578...24,987,528

G

dynein, axonemal, assembly factor 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAAF5 mRNA

NCBI chr12:20,567,482...20,606,600
Ensembl chr12:15,453,636...15,492,739

G

dynein, axonemal, heavy chain 6

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAH6 mRNA

NCBI chr 4:106,622,235...106,842,461
Ensembl chr 4:105,064,125...105,284,376

G

dynein axonemal intermediate chain 7

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAI7 mRNA

NCBI chr 4:178,143,499...178,179,871
Ensembl chr 4:178,143,500...178,179,980

G

DnaJ heat shock protein family (Hsp40) member A3

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAJA3 mRNA

NCBI chr10:11,361,168...11,386,599
Ensembl chr10:10,854,732...10,880,161

G

DnaJ heat shock protein family (Hsp40) member B5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DNAJB5 mRNA

NCBI chr 5:61,972,637...61,981,887
Ensembl chr 5:57,176,845...57,185,490

G

DnaJ heat shock protein family (Hsp40) member B7

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAJB7 mRNA

NCBI chr 7:114,812,886...114,814,200
Ensembl chr 7:112,932,616...112,945,537

G

DnaJ heat shock protein family (Hsp40) member C2

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAJC2 mRNA

NCBI chr 4:14,162,490...14,189,662
Ensembl chr 4:13,270,191...13,297,431

G

DnaJ heat shock protein family (Hsp40) member C24

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DNAJC24 mRNA

NCBI chr 3:92,450,631...92,486,004
Ensembl chr 3:92,450,639...92,485,901

G

DnaJ heat shock protein family (Hsp40) member C3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DNAJC3 mRNA

NCBI chr15:102,432,667...102,475,643
Ensembl chr15:96,025,624...96,065,181

G

dedicator of cytokinesis 11

increases expression

perfluoro-n-nonanoic acid results in increased expression of DOCK11 mRNA

NCBI chr X:119,997,523...120,180,643
Ensembl chr X:115,131,909...115,314,854

G

deoxyhypusine hydroxylase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DOHH mRNA

NCBI chr 7:8,321,466...8,326,305
Ensembl chr 7:8,321,466...8,326,289

G

dolichyl-phosphate N-acetylglucosaminephosphotransferase 1

affects methylation

perfluoro-n-nonanoic acid affects the methylation of DPAGT1 gene

NCBI chr 8:44,664,055...44,671,102
Ensembl chr 8:44,664,071...44,671,087

G

diphthamide biosynthesis 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of DPH2 mRNA

NCBI chr 5:131,428,434...131,431,394
Ensembl chr 5:131,428,268...131,431,395

G

diphthamide biosynthesis 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of DPH3 mRNA

NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265

G

dipeptidylpeptidase 4

decreases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of DPP4 mRNA
[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] affects the expression of DPP4 mRNA

PMID:32588087 PMID:36270329

NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:46,962,243...47,043,901

G

dihydropyrimidine dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DPYD mRNA

NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:206,609,122...207,474,982

G

dihydropyrimidinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DPYS mRNA

NCBI chr 7:72,707,566...72,814,183
Ensembl chr 7:70,835,789...70,929,231

G

dopamine receptor D2

multiple interactions

[perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in increased expression of DRD2 mRNA

NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875

G

dopamine receptor D5

increases expression

perfluoro-n-nonanoic acid results in increased expression of DRD5 mRNA

NCBI chr14:76,700,244...76,703,344
Ensembl chr14:72,489,347...72,490,774

G

desmocollin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DSC1 mRNA

NCBI chr18:11,774,711...11,831,868
Ensembl chr18:11,502,003...11,528,494

G

dermatan sulfate epimerase-like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DSEL mRNA

NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647

G

D-aminoacyl-tRNA deacylase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DTD1 mRNA

NCBI chr 3:131,995,870...132,158,646
Ensembl chr 3:131,995,861...132,158,659

G

dihydrouridine synthase 3-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of DUS3L mRNA

NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655

G

dihydrouridine synthase 4-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of DUS4L mRNA

NCBI chr 6:48,228,111...48,242,553
Ensembl chr 6:48,228,111...48,242,449

G

dual specificity phosphatase 10

increases expression

perfluoro-n-nonanoic acid results in increased expression of DUSP10 mRNA

NCBI chr13:98,145,317...98,183,304
Ensembl chr13:95,614,292...95,651,716

G

dual specificity phosphatase 12

increases expression

perfluoro-n-nonanoic acid results in increased expression of DUSP12 mRNA

NCBI chr13:85,654,914...85,666,431
Ensembl chr13:83,122,193...83,131,285

G

dual specificity phosphatase 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of DUSP5 mRNA

NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:252,538,449...252,551,818

G

dishevelled segment polarity protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DVL1 mRNA

NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:166,456,686...166,468,664

G

dishevelled segment polarity protein 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DVL3 mRNA

NCBI chr11:93,869,834...93,887,013
Ensembl chr11:80,366,117...80,382,462

G

E2F transcription factor 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of E2F5 mRNA

NCBI chr 2:86,997,331...87,012,908
Ensembl chr 2:86,997,332...87,012,990

G

E2F transcription factor 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of E2F8 mRNA

NCBI chr 1:107,701,985...107,720,538
Ensembl chr 1:98,565,717...98,584,098

G

EBP, cholestenol delta-isomerase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EBP mRNA

NCBI chr X:16,971,372...16,977,782
Ensembl chr X:14,299,448...14,305,826

G

enoyl-CoA hydratase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ECH1 mRNA

NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:84,112,751...84,120,795

G

enoyl CoA hydratase domain containing 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ECHDC2 mRNA

NCBI chr 5:128,144,241...128,163,611
Ensembl chr 5:122,916,134...122,934,859

G

enoyl-CoA delta isomerase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ECI1 mRNA

NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,456,563...13,470,061

G

enoyl-CoA delta isomerase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ECI2 mRNA

NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781

G

epithelial cell transforming 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ECT2 mRNA

NCBI chr 2:111,904,522...111,966,786
Ensembl chr 2:109,975,813...110,037,911

G

eukaryotic translation elongation factor 1 alpha 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EEF1A1 mRNA

NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:79,341,557...79,344,839

G

eukaryotic translation elongation factor 1 delta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EEF1D mRNA

NCBI chr 7:109,462,645...109,478,021
Ensembl chr 7:107,581,930...107,608,799

G

eukaryotic translation elongation factor 1 gamma

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EEF1G mRNA

NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:205,860,698...205,872,382

G

eukaryotic translation elongation factor 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EEF2 mRNA

NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:8,533,116...8,559,183

G

eukaryotic elongation factor 2 lysine methyltransferase

increases expression

perfluoro-n-nonanoic acid results in increased expression of EEF2KMT mRNA

NCBI chr10:10,336,933...10,349,463
Ensembl chr10:10,336,974...10,347,039

G

EF-hand calcium binding domain 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of EFCAB2 mRNA

NCBI chr13:90,152,002...90,237,918
Ensembl chr13:90,152,185...90,238,218

G

ephrin A4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EFNA4 mRNA

NCBI chr 2:177,046,463...177,050,713
Ensembl chr 2:174,748,724...174,752,979

G

EFR3 homolog B

increases expression

perfluoro-n-nonanoic acid results in increased expression of EFR3B mRNA

NCBI chr 6:26,947,436...27,021,113
Ensembl chr 6:26,948,540...27,020,933

G

epidermal growth factor receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EGFR mRNA

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of EHHADH mRNA
perfluoro-n-nonanoic acid results in decreased expression of EHHADH mRNA

PMID:23567314 PMID:25543169 PMID:28558994 PMID:32588087

NCBI chr11:92,746,409...92,779,647
Ensembl chr11:79,241,938...79,275,188

G

eukaryotic translation initiation factor 2 subunit beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of EIF2S2 mRNA

NCBI chr 3:163,834,846...163,855,733
Ensembl chr 3:143,373,686...143,395,432

G

eukaryotic translation initiation factor 3, subunit D

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EIF3D mRNA

NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206

G

eukaryotic translation initiation factor 4E binding protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of EIF4EBP1 mRNA

NCBI chr16:71,495,457...71,508,845
Ensembl chr16:64,790,226...64,805,984

G

eukaryotic translation initiation factor 4E binding protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of EIF4EBP3 mRNA

NCBI chr18:28,263,089...28,268,033
Ensembl chr18:28,162,311...28,268,024

G

eukaryotic translation initiation factor 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of EIF5 mRNA

NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656

G

eukaryotic translation initiation factor 6

increases expression

perfluoro-n-nonanoic acid results in increased expression of EIF6 mRNA

NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401

G

E74 like ETS transcription factor 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of ELF3 mRNA

NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481

G

engulfment and cell motility 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ELMO1 mRNA

NCBI chr17:48,982,188...49,518,525
Ensembl chr17:44,286,485...44,822,788

G

ELOVL fatty acid elongase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ELOVL2 mRNA

NCBI chr17:23,750,350...23,790,601
Ensembl chr17:23,544,568...23,584,848

G

ELOVL fatty acid elongase 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ELOVL6 mRNA

NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:218,063,804...218,171,186

G

Emx2 opposite strand/antisense RNA

increases expression

perfluoro-n-nonanoic acid results in increased expression of EMX2OS mRNA

NCBI chr 1:258,569,637...258,626,810

G

endonuclease G

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ENDOG mRNA

NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:13,449,086...13,451,932

G

glutamyl aminopeptidase

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of ENPEP mRNA

NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:217,782,005...217,851,947

G

ectonucleoside triphosphate diphosphohydrolase 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of ENTPD5 mRNA

NCBI chr 6:109,750,210...109,786,376
Ensembl chr 6:104,019,185...104,055,530

G

ectonucleoside triphosphate diphosphohydrolase 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ENTPD7 mRNA

NCBI chr 1:252,508,594...252,550,269
Ensembl chr 1:242,559,365...242,601,447

G

ectonucleoside triphosphate diphosphohydrolase 8

increases expression

perfluoro-n-nonanoic acid results in increased expression of ENTPD8 mRNA

NCBI chr 3:7,885,277...7,895,517
Ensembl chr 3:7,889,909...7,895,296

G

erythrocyte membrane protein band 4.1-like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of EPB41L1 mRNA

NCBI chr 3:165,389,295...165,512,821
Ensembl chr 3:144,984,640...145,052,721

G

erythrocyte membrane protein band 4.1-like 3

affects methylation

perfluoro-n-nonanoic acid affects the methylation of EPB41L3 gene

NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607

G

epithelial cell adhesion molecule

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPCAM mRNA

NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:6,878,237...6,896,127

G

Eph receptor A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPHA1 mRNA

NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846

G

Eph receptor A2

increases expression

perfluoro-n-nonanoic acid results in increased expression of EPHA2 mRNA

NCBI chr 5:158,888,629...158,917,100
Ensembl chr 5:153,605,644...153,634,117

G

EPH receptor A5

increases expression

perfluoro-n-nonanoic acid results in increased expression of EPHA5 mRNA

NCBI chr14:23,653,393...24,020,129
Ensembl chr14:23,653,393...24,017,317

G

EPH receptor B4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPHB4 mRNA

NCBI chr12:24,963,174...24,988,473
Ensembl chr12:19,326,427...19,351,314

G

epoxide hydrolase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPHX2 mRNA

NCBI chr15:44,465,447...44,503,157
Ensembl chr15:40,289,902...40,327,615

G

Epsin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPN1 mRNA

NCBI chr 1:68,742,491...68,760,570
Ensembl chr 1:68,742,789...68,758,874

G

elongin BC and polycomb repressive complex 2 associated protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPOP mRNA

NCBI chr10:82,624,392...82,625,912
Ensembl chr10:82,624,392...82,625,912

G

glutamyl-prolyl-tRNA synthetase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of EPRS1 mRNA

NCBI chr13:99,431,955...99,503,510
Ensembl chr13:96,901,575...96,971,966

G

erb-b2 receptor tyrosine kinase 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ERBB3 mRNA

NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:996,225...1,015,525

G

epiregulin

increases expression

perfluoro-n-nonanoic acid results in increased expression of EREG mRNA

NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,027,287...17,041,062

G

ergosterol biosynthesis 28 homolog

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ERG28 mRNA

NCBI chr 6:105,474,112...105,483,078
Ensembl chr 6:105,474,113...105,483,078

G

glutamate-rich 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ERICH2 mRNA

NCBI chr 3:55,310,993...55,347,701
Ensembl chr 3:55,310,993...55,347,184

G

glutamate-rich 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of ERICH5 mRNA

NCBI chr 7:65,655,829...65,682,221
Ensembl chr 7:65,657,204...65,680,207

G

glutamate-rich 6B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ERICH6B mRNA

NCBI chr15:50,979,066...51,014,394

G

endoplasmic reticulum metallopeptidase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ERMP1 mRNA

NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:227,387,920...227,436,909

G

endoplasmic reticulum to nucleus signaling 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ERN1 mRNA

NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029

G

endoplasmic reticulum protein 27

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ERP27 mRNA

PMID:25812627 PMID:32588087

NCBI chr 4:169,804,656...169,821,660
Ensembl chr 4:169,804,658...169,821,660

G

establishment of sister chromatid cohesion N-acetyltransferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ESCO2 mRNA

NCBI chr15:44,210,124...44,230,785
Ensembl chr15:40,034,568...40,055,306
Ensembl chr15:40,034,568...40,055,306

G

endothelial cell-specific molecule 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ESM1 protein

NCBI chr 2:46,609,253...46,617,991
Ensembl chr 2:44,876,067...44,884,804

G

extra spindle pole bodies like 1, separase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ESPL1 mRNA

NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:133,424,130...133,450,984

G

estrogen receptor 1

multiple interactions

perfluoro-n-nonanoic acid binds to and results in increased activity of ESR1 protein

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

electron transfer flavoprotein subunit beta lysine methyltransferase

increases expression

perfluoro-n-nonanoic acid results in increased expression of ETFBKMT mRNA

NCBI chr 4:182,140,492...182,204,635
Ensembl chr 4:182,140,559...182,150,305

G

ETS variant transcription factor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ETV1 mRNA

NCBI chr 6:61,316,836...61,408,985
Ensembl chr 6:55,590,234...55,681,775

G

ETS variant transcription factor 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ETV4 mRNA

NCBI chr10:87,206,977...87,222,202
Ensembl chr10:86,706,749...86,721,974

G

exosome component 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of EXOSC5 mRNA

NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265

G

exosome component 8

increases expression

perfluoro-n-nonanoic acid results in increased expression of EXOSC8 mRNA

NCBI chr 2:141,080,568...141,087,112
Ensembl chr 2:138,930,405...138,936,928

G

exostosin-like glycosyltransferase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of EXTL1 mRNA

NCBI chr 5:151,857,629...151,872,830
Ensembl chr 5:146,573,912...146,589,115

G

EYA transcriptional coactivator and phosphatase 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EYA4 mRNA

NCBI chr 1:23,991,431...24,235,132
Ensembl chr 1:22,172,275...22,415,976

G

coagulation factor X

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F10 mRNA

NCBI chr16:83,170,973...83,190,280
Ensembl chr16:76,468,838...76,488,141

G

coagulation factor XI

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F11 mRNA

NCBI chr16:53,720,502...53,741,547
Ensembl chr16:46,986,107...47,008,437

G

coagulation factor XIII B chain

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F13B mRNA

NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381

G

coagulation factor II (thrombin) receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F2R mRNA

NCBI chr 2:28,604,066...28,620,579
Ensembl chr 2:26,868,404...26,885,870

G

coagulation factor III, tissue factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F3 mRNA

NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:209,826,959...209,838,668

G

coagulation factor IX

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F9 mRNA

NCBI chr X:138,352,334...138,396,835
Ensembl chr X:138,352,298...138,396,835

G

fatty acid binding protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of FABP1 mRNA

NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788

G

fatty acid binding protein 4

multiple interactions

[perfluorooctane sulfonic acid co-treated with perfluorooctanoic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in increased expression of FABP4 mRNA

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578

G

family with sequence similarity 168, member A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FAM168A mRNA

NCBI chr 1:164,469,447...164,615,542
Ensembl chr 1:155,057,352...155,201,220

G

family with sequence similarity 171, member A2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FAM171A2 mRNA

NCBI chr10:87,393,888...87,404,051
Ensembl chr10:87,394,007...87,404,053

G

family with sequence similarity 204, member A

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAM204A mRNA

NCBI chr 1:259,328,551...259,366,726
Ensembl chr 1:259,337,709...259,367,077

G

FAM20A, golgi associated secretory pathway pseudokinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FAM20A mRNA

NCBI chr10:95,136,799...95,197,176
Ensembl chr10:94,642,850...94,697,672

G

family with sequence similarity 222, member B

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAM222B mRNA

NCBI chr10:62,986,571...63,052,350
Ensembl chr10:62,986,571...63,052,350

G

family with sequence similarity 241 member A

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAM241A mRNA

NCBI chr 2:216,344,563...216,375,193
Ensembl chr 2:216,343,822...216,375,242

G

family with sequence similarity 83, member D

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FAM83D mRNA

NCBI chr 3:167,841,748...167,861,062
Ensembl chr 3:147,421,908...147,441,192

G

family with sequence similarity 89, member A

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAM89A mRNA

NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631

G

family with sequence similarity 98, member C

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAM98C mRNA

NCBI chr 1:84,452,806...84,456,414
Ensembl chr 1:84,452,814...84,456,385

G

FA complementation group A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FANCA mRNA

NCBI chr19:68,210,562...68,271,080
Ensembl chr19:51,304,021...51,362,527

G

phenylalanyl-tRNA synthetase subunit beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of FARSB mRNA

NCBI chr 9:87,336,321...87,395,546
Ensembl chr 9:79,887,842...79,947,045

G

Fas cell surface death receptor

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAS mRNA

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591

G

fatty acid synthase

decreases expression
increases activity

perfluoro-n-nonanoic acid results in decreased expression of FASN mRNA
perfluoro-n-nonanoic acid results in increased activity of FASN protein

PMID:26056853 PMID:32588087

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261

G

Fas-activated serine/threonine kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FASTK mRNA

NCBI chr 4:10,732,273...10,736,332
Ensembl chr 4:10,732,256...10,737,430

G

fatty acid hydroxylase domain containing 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FAXDC2 mRNA

NCBI chr10:42,747,323...42,772,156
Ensembl chr10:42,246,868...42,271,871

G

fibrillarin-like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of FBLL1 mRNA

NCBI chr10:20,258,656...20,260,299
Ensembl chr10:20,258,656...20,260,299

G

fibrosin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FBRS mRNA

NCBI chr 1:191,520,148...191,534,510
Ensembl chr 1:182,089,844...182,103,828

G

F-box protein 32

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FBXO32 mRNA

NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:89,730,232...89,765,436

G

F-box protein 39

increases expression

perfluoro-n-nonanoic acid results in increased expression of FBXO39 mRNA

NCBI chr10:56,929,699...56,934,911
Ensembl chr10:56,932,297...56,934,906

G

F-box protein 41

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FBXO41 mRNA

NCBI chr 4:119,565,012...119,597,042
Ensembl chr 4:118,010,978...118,039,406

G

F-box and WD repeat domain containing 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FBXW7 mRNA

NCBI chr 2:172,447,738...172,609,591
Ensembl chr 2:170,149,694...170,309,941

G

farnesyl diphosphate farnesyl transferase 1

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of FDFT1 mRNA
perfluoro-n-nonanoic acid results in increased expression of FDFT1 mRNA

PMID:22071372 PMID:32588087

NCBI chr15:41,588,114...41,616,168
Ensembl chr15:37,412,146...37,440,287

G

farnesyl diphosphate synthase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FDPS mRNA

NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:174,486,665...174,507,776

G

ferrochelatase

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of FECH mRNA

NCBI chr18:60,215,325...60,248,525
Ensembl chr18:57,945,122...57,979,348

G

flap structure-specific endonuclease 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FEN1 mRNA

NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:206,844,884...206,850,003

G

fetuin B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FETUB mRNA

NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135

G

fibroblast growth factor 21

increases expression

perfluoro-n-nonanoic acid results in increased expression of FGF21 mRNA

NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:96,083,441...96,090,454

G

fibroblast growth factor 23

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FGF23 protein

NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:159,914,272...159,923,821

G

four and a half LIM domains 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of FHL2 mRNA

NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:45,388,981...45,431,192

G

filamin B

increases expression

perfluoro-n-nonanoic acid results in increased expression of FLNB mRNA

NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006

G

Fms related receptor tyrosine kinase 3 ligand

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FLT3LG mRNA

NCBI chr 1:104,751,518...104,756,925
Ensembl chr 1:95,609,370...95,620,463

G

FLYWCH-type zinc finger 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FLYWCH1 mRNA

NCBI chr10:13,279,232...13,298,955
Ensembl chr10:12,774,653...12,794,267

G

formin-like 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of FMNL2 mRNA

NCBI chr 3:37,348,791...37,624,746
Ensembl chr 3:37,348,574...37,624,754

G

flavin containing dimethylaniline monoxygenase 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FMO3 mRNA

NCBI chr13:77,838,899...77,868,869
Ensembl chr13:75,309,374...75,328,028

G

flavin containing dimethylaniline monoxygenase 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FMO4 mRNA

NCBI chr13:77,687,909...77,706,100
Ensembl chr13:75,154,684...75,172,874

G

flavin containing dimethylaniline monoxygenase 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FMO5 mRNA

NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:185,222,204...185,249,693

G

fibronectin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FN1 mRNA

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:73,196,044...73,264,678

G

forkhead box A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FOXA1 mRNA

NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:75,103,503...75,136,188

G

forkhead box C1

increases expression

perfluoro-n-nonanoic acid results in increased expression of FOXC1 mRNA

NCBI chr17:32,840,119...32,844,100
Ensembl chr17:32,633,142...32,634,803

G

forkhead box M1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FOXM1 mRNA

NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:161,638,816...161,650,684

G

forkhead box O3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FOXO3 mRNA

NCBI chr20:47,251,968...47,348,254
Ensembl chr20:45,672,995...45,764,561

G

forkhead box O4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FOXO4 mRNA

NCBI chr X:70,425,218...70,432,120
Ensembl chr X:66,385,558...66,392,115

G

FRAS1 related extracellular matrix 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FREM2 mRNA

NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785

G

follicle stimulating hormone subunit beta

multiple interactions

[perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in decreased expression of FSHB protein

NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370

G

follicle stimulating hormone receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FSHR mRNA

NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:5,198,825...5,406,785

G

ferritin heavy chain 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of FTH1 mRNA

NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:206,627,103...206,725,424

G

Fus RNA binding protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FUS mRNA

PMID:25812627 PMID:38568856

NCBI chr 1:192,007,011...192,020,887
Ensembl chr 1:182,576,545...182,590,414

G

Friend virus susceptibility 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of C19ORF48P mRNA

NCBI chr 1:94,730,839...94,736,791
Ensembl chr 1:94,730,606...94,737,594

G

FYVE and coiled-coil domain autophagy adaptor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FYCO1 mRNA

NCBI chr 8:123,412,105...123,479,315
Ensembl chr 8:123,412,112...123,479,021

G

frizzled class receptor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FZD1 mRNA

NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643

G

glucose-6-phosphatase catalytic subunit 1

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of G6PC1 mRNA
perfluoro-n-nonanoic acid results in decreased expression of G6PC1 mRNA

PMID:22387981 PMID:32588087

NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,257,668...86,333,804

G

glucose-6-phosphate dehydrogenase

increases activity

perfluoro-n-nonanoic acid results in increased activity of G6PD protein

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801

G

GABA type A receptor associated protein like 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of GABARAPL2 mRNA

NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628

G

gamma-aminobutyric acid type A receptor subunit gamma 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of GABRG2 mRNA

NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346

G

growth arrest and DNA-damage-inducible, alpha

increases expression

perfluoro-n-nonanoic acid results in increased expression of GADD45A mRNA

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115

G

growth arrest and DNA-damage-inducible, gamma

increases expression

perfluoro-n-nonanoic acid results in increased expression of GADD45G mRNA

NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,376,839...13,378,610

G

polypeptide N-acetylgalactosaminyltransferase 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GALNT11 mRNA

NCBI chr 4:10,571,464...10,604,974
Ensembl chr 4:9,837,629...9,871,140

G

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

increases expression

perfluoro-n-nonanoic acid results in increased expression of GART mRNA

NCBI chr11:44,351,841...44,377,086
Ensembl chr11:30,865,889...30,891,125

G

growth arrest-specific 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GAS2 mRNA

NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619

G

growth arrest-specific 2 like 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GAS2L3 mRNA

NCBI chr 7:23,803,578...23,836,816
Ensembl chr 7:23,806,310...23,836,411

G

growth arrest specific 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of GAS5 mRNA

NCBI chr13:75,836,963...75,840,284

G

GATA zinc finger domain containing 2A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GATAD2A mRNA

NCBI chr16:19,429,578...19,520,320
Ensembl chr16:19,429,578...19,519,587

G

glucosylceramidase beta 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GBA3 mRNA

NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653

G

guanylate binding protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GBP2 mRNA

NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571

G

guanylate binding protein 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GBP7 mRNA

NCBI chr 2:233,948,774...233,970,532
Ensembl chr 2:231,275,640...231,297,278

G

GRIP and coiled-coil domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GCC1 mRNA

NCBI chr 4:57,030,817...57,042,682
Ensembl chr 4:57,032,314...57,042,663

G

glutaryl-CoA dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GCDH mRNA

NCBI chr19:40,168,038...40,174,536
Ensembl chr19:23,263,264...23,269,681

G

glucokinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GCK mRNA

NCBI chr14:84,999,019...85,041,098
Ensembl chr14:80,785,060...80,826,995

G

glutamate-cysteine ligase, catalytic subunit

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GCLC mRNA

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression

perfluoro-n-nonanoic acid results in increased expression of GCLM mRNA

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535

G

guanine deaminase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GDA mRNA

NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:218,906,815...218,982,416

G

growth differentiation factor 15

increases expression

perfluoro-n-nonanoic acid results in increased expression of GDF15 mRNA

NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,805,239...18,808,055

G

guided entry of tail-anchored proteins factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of WRB mRNA

NCBI chr11:35,438,555...35,460,156
Ensembl chr11:35,445,815...35,459,973

G

glial fibrillary acidic protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GFAP mRNA

NCBI chr10:88,352,987...88,361,661
Ensembl chr10:87,852,890...87,861,589

G

gamma-glutamyl hydrolase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GGH mRNA

NCBI chr 5:38,326,747...38,349,655
Ensembl chr 5:33,529,880...33,552,787

G

GINS complex subunit 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GINS1 mRNA

NCBI chr 3:160,184,920...160,206,334
Ensembl chr 3:139,724,490...139,745,936

G

gap junction protein, alpha 10

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GJA10 mRNA

NCBI chr 5:51,787,407...51,799,827
Ensembl chr 5:46,992,946...46,996,570

G

gap junction protein, beta 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GJB1 mRNA

NCBI chr X:70,541,845...70,549,776
Ensembl chr X:66,501,820...66,509,925

G

gastrokine 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of GKN2 mRNA

NCBI chr 4:121,335,642...121,381,680
Ensembl chr 4:119,818,280...119,824,363

G

galactosidase, beta 1-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of GLB1L mRNA

NCBI chr 9:76,693,325...76,705,548
Ensembl chr 9:76,695,173...76,705,510

G

glycine decarboxylase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLDC mRNA

NCBI chr 1:237,296,753...237,375,620
Ensembl chr 1:227,883,249...227,962,097

G

GLI family zinc finger 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLI1 mRNA

NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:63,156,926...63,169,251

G

GLIS family zinc finger 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of GLIS3 mRNA

NCBI chr 1:225,976,029...226,395,849
Ensembl chr 1:225,976,326...226,395,899

G

glutaminase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLS2 mRNA

NCBI chr 7:1,201,757...1,218,014
Ensembl chr 7:617,288...633,426

G

glutamate-ammonia ligase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLUL mRNA

NCBI chr13:68,519,500...68,585,554
Ensembl chr13:66,025,630...66,035,108

G

glycine-N-acyltransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLYAT mRNA

NCBI chr 1:219,128,798...219,149,615
Ensembl chr 1:209,704,268...209,724,942

G

glycerate kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLYCTK mRNA

NCBI chr 8:106,795,461...106,802,675
Ensembl chr 8:106,797,343...106,802,397

G

GNAS complex locus

increases expression

perfluoro-n-nonanoic acid results in increased expression of GNAS mRNA

NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

G

G protein subunit gamma transducin 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GNGT1 mRNA

NCBI chr 4:32,960,945...32,963,930
Ensembl chr 4:32,006,267...32,009,252

G

G protein nucleolar 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of GNL3 mRNA

NCBI chr16:6,213,844...6,220,029
Ensembl chr16:6,207,402...6,213,392

G

glycine N-methyltransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GNMT mRNA

NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:14,254,675...14,258,434

G

golgi phosphoprotein 3-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of GOLPH3L mRNA

NCBI chr 2:185,840,879...185,872,037
Ensembl chr 2:183,153,301...183,183,083

G

glycerophosphocholine phosphodiesterase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GPCPD1 mRNA

NCBI chr 3:140,240,574...140,285,469
Ensembl chr 3:119,787,682...119,832,517

G

glycerol-3-phosphate dehydrogenase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPD1 mRNA

NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:130,844,138...130,851,529

G

G protein-coupled estrogen receptor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPER1 mRNA

NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889

G

G protein-coupled receptor 22

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPR22 mRNA

NCBI chr 6:54,037,998...54,044,994
Ensembl chr 6:48,310,505...48,317,486

G

G protein-coupled receptor 61

increases expression

perfluoro-n-nonanoic acid results in increased expression of GPR61 mRNA

NCBI chr 2:198,471,430...198,477,827
Ensembl chr 2:195,782,752...195,789,621

G

G protein-coupled receptor 83

increases expression

perfluoro-n-nonanoic acid results in increased expression of GPR83 mRNA

NCBI chr 8:19,974,995...19,985,483
Ensembl chr 8:11,693,540...11,704,028

G

G-protein coupled receptor 88

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPR88 mRNA

NCBI chr 2:206,876,373...206,885,034
Ensembl chr 2:204,191,427...204,199,733

G

G protein-coupled receptor, class C, group 5, member B

increases expression

perfluoro-n-nonanoic acid results in increased expression of GPRC5B mRNA

NCBI chr 1:182,748,247...182,772,711
Ensembl chr 1:173,316,907...173,340,932

G

G protein-regulated inducer of neurite outgrowth 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPRIN1 mRNA

NCBI chr17:9,863,881...9,876,832
Ensembl chr17:9,863,571...9,876,915

G

glutamic--pyruvic transaminase

decreases expression
increases activity
decreases activity

perfluoro-n-nonanoic acid results in decreased expression of GPT mRNA
perfluoro-n-nonanoic acid results in increased activity of GPT protein
perfluoro-n-nonanoic acid results in decreased activity of GPT protein

PMID:26056853 PMID:29156323 PMID:32588087

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494

G

glutamic--pyruvic transaminase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of GPT2 mRNA

NCBI chr19:37,700,023...37,734,551
Ensembl chr19:21,517,621...21,560,610

G

glutathione peroxidase 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPX8 mRNA

NCBI chr 2:46,409,646...46,413,401
Ensembl chr 2:44,676,454...44,680,195

G

growth factor receptor bound protein 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GRB7 mRNA

NCBI chr10:83,936,538...83,949,344
Ensembl chr10:83,444,004...83,453,052

G

grainyhead-like transcription factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GRHL1 mRNA

NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301

G

glutaredoxin and cysteine rich domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GRXCR1 mRNA

NCBI chr14:40,358,077...40,480,493
Ensembl chr14:40,004,169...40,126,571

G

glycogen synthase kinase 3 beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of GSK3B protein modified form

NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione S-transferase alpha 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GSTA1 mRNA

NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GSTA2 mRNA

NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GSTA4 mRNA

NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase mu 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of GSTM4 mRNA

NCBI chr 2:198,356,114...198,373,487
Ensembl chr 2:195,680,004...195,685,323

G

glutathione S-transferase, mu 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of GSTM3 mRNA

PMID:28558994 PMID:35337807

NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:195,531,495...195,534,553

G

glycosyltransferase-like domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GTDC1 mRNA

NCBI chr 3:28,766,640...29,161,668
Ensembl chr 3:28,766,645...29,162,271

G

GTF2I repeat domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GTF2IRD1 mRNA

NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040

G

GTP binding protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of GTPBP2 mRNA

NCBI chr 9:22,311,532...22,321,405
Ensembl chr 9:14,813,964...14,823,241

G

G-2 and S-phase expressed 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GTSE1 mRNA

NCBI chr 7:118,829,793...118,846,662
Ensembl chr 7:116,950,053...116,966,806

G

GTP binding elongation factor GUF1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GUF1 mRNA

NCBI chr14:38,537,953...38,557,331
Ensembl chr14:38,537,953...38,557,331

G

glycogen synthase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GYS2 mRNA

NCBI chr 4:177,096,063...177,137,236
Ensembl chr 4:175,365,054...175,406,228

G

H1.0 linker histone

increases expression

perfluoro-n-nonanoic acid results in increased expression of H1-0 mRNA

NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:110,592,208...110,594,694

G

H1.4 linker histone, cluster member

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of H1-4 mRNA

NCBI chr17:41,914,425...41,915,206
Ensembl chr17:41,486,560...41,487,403

G

3-hydroxyanthranilate 3,4-dioxygenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HAAO mRNA

NCBI chr 6:16,598,325...16,617,590
Ensembl chr 6:10,845,771...10,864,877

G

hyaluronan binding protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HABP2 mRNA

NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

increases expression

perfluoro-n-nonanoic acid results in increased expression of HADHA mRNA

PMID:22071372 PMID:23567314

NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:26,187,956...26,227,869

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of HADHB mRNA

NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:26,153,578...26,184,869

G

hydroxyacyl glutathione hydrolase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HAGH mRNA

NCBI chr10:14,379,400...14,394,046
Ensembl chr10:13,875,241...13,889,504

G

histidine ammonia lyase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HAL mRNA

NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:28,006,972...28,037,701

G

hydroxyacid oxidase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HAO2 mRNA

NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425

G

hemoglobin subunit beta

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of HBB-B1 mRNA

NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:158,120,200...158,252,012

G

histone deacetylase 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HDAC7 mRNA

NCBI chr 7:130,803,013...130,841,181
Ensembl chr 7:128,923,920...128,962,072

G

HDGF like 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HDGFL2 mRNA

NCBI chr 9:996,687...1,016,352
Ensembl chr 9:909,614...929,186

G

HEAT repeat containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of HEATR1 mRNA

NCBI chr17:62,745,008...62,785,609
Ensembl chr17:58,051,700...58,093,948

G

heart development protein with EGF-like domains 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HEG1 mRNA

NCBI chr11:80,512,096...80,600,150
Ensembl chr11:66,957,190...67,095,051

G

hexosaminidase D

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HEXD mRNA

NCBI chr10:106,479,781...106,498,799
Ensembl chr10:106,480,194...106,498,799

G

homogentisate 1, 2-dioxygenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HGD mRNA

NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323

G

hepatocyte growth factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HGF protein

NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:18,677,101...18,745,409

G

hematopoietically expressed homeobox

increases expression

perfluoro-n-nonanoic acid results in increased expression of HHEX mRNA

NCBI chr 1:244,602,945...244,608,532
Ensembl chr 1:235,190,455...235,196,042

G

hypoxia inducible factor 1 subunit alpha

affects methylation

perfluoro-n-nonanoic acid affects the methylation of HIF1A gene

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261

G

histone cluster 1 H2a family member I like 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of H3C6 mRNA

NCBI chr17:41,996,216...41,997,128
Ensembl chr17:41,568,471...41,569,109

G

histone cluster 1, H2bc

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of H2BC21 mRNA

NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642

G

hemojuvelin BMP co-receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HJV mRNA

NCBI chr 2:186,754,801...186,758,708
Ensembl chr 2:184,065,970...184,069,850

G

hexokinase domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of HKDC1 mRNA

NCBI chr20:30,335,322...30,373,792
Ensembl chr20:30,335,628...30,373,867

G

high mobility group AT-hook 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HMGA1 mRNA

NCBI chr20:5,612,902...5,620,596
Ensembl chr20:5,611,694...5,618,752

G

high mobility group AT-hook 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HMGA2 mRNA

NCBI chr 7:57,762,710...57,884,555
Ensembl chr 7:55,880,112...55,994,784

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HMGCR mRNA

PMID:21641976 PMID:32588087

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HMGCS1 mRNA

NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:51,649,497...51,667,100

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of HMGCS2 mRNA
perfluoro-n-nonanoic acid results in decreased expression of HMGCS2 mRNA

PMID:23567314 PMID:32588087

NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:185,875,616...185,902,130

G

hyaluronan-mediated motility receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HMMR mRNA

NCBI chr10:25,635,249...25,665,389
Ensembl chr10:25,132,977...25,163,060

G

heme oxygenase 1

increases expression
affects expression

perfluoro-n-nonanoic acid results in increased expression of HMOX1 mRNA
perfluoro-n-nonanoic acid affects the expression of HMOX1 protein

PMID:32588087 PMID:38537583

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079

G

hepatocyte nuclear factor 4, alpha

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HNF4A mRNA

NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:152,186,787...152,248,320

G

histamine N-methyltransferase

increases expression

perfluoro-n-nonanoic acid results in increased expression of HNMT mRNA

NCBI chr 3:26,978,274...27,010,291
Ensembl chr 3:6,591,463...6,624,012

G

heterogeneous nuclear ribonucleoprotein A0

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HNRNPA0 mRNA

NCBI chr17:6,513,129...6,515,786
Ensembl chr17:6,507,275...6,509,375

G

heterogeneous nuclear ribonucleoprotein U-like 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HNRNPUL2 mRNA

NCBI chr 1:205,713,431...205,725,553
Ensembl chr 1:205,711,886...205,725,553

G

homeo box A5

multiple interactions
increases expression

PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXA5 mRNA]

NCBI chr 4:82,632,958...82,636,851
Ensembl chr 4:81,302,353...81,306,234

G

homeo box B7

decreases expression
multiple interactions
increases expression

perfluoro-n-nonanoic acid results in decreased expression of HOXB7 protein
NFE2L2 protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXB7 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXB7 mRNA]

NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034

G

homeo box B9

increases expression

perfluoro-n-nonanoic acid results in increased expression of HOXB9 mRNA

NCBI chr10:81,733,857...81,737,363
Ensembl chr10:81,237,312...81,240,818

G

homeo box C5

increases expression
affects expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of HOXC5 mRNA
perfluoro-n-nonanoic acid affects the expression of HOXC5 protein
NFE2L2 protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXC5 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXC5 mRNA]

NCBI chr 7:134,150,988...134,154,410
Ensembl chr 7:134,150,988...134,154,410

G

homeo box D10

multiple interactions
increases expression

NFE2L2 protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXD10 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXD10 mRNA]

NCBI chr 3:80,001,947...80,005,156
Ensembl chr 3:59,594,516...59,597,725

G

homeobox D8

increases expression

perfluoro-n-nonanoic acid results in increased expression of HOXD8 mRNA

NCBI chr 3:59,607,793...59,610,359
Ensembl chr 3:59,607,996...59,610,361

G

15-hydroxyprostaglandin dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HPGD mRNA

NCBI chr16:38,996,876...39,034,831
Ensembl chr16:33,986,266...34,024,228

G

HRas proto-oncogene, GTPase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HRAS mRNA

NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615

G

histidine rich carboxyl terminus 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HRCT1 mRNA

NCBI chr 5:62,778,112...62,778,954
Ensembl chr 5:57,982,470...57,982,790

G

histidine-rich glycoprotein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HRG mRNA

NCBI chr11:91,559,087...91,573,982
Ensembl chr11:78,054,498...78,069,389

G

hydroxysteroid 11-beta dehydrogenase 1

multiple interactions

[perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in decreased expression of HSD11B1 mRNA

NCBI chr13:107,277,526...107,327,462
Ensembl chr13:104,728,539...104,788,687

G

hydroxysteroid 11-beta dehydrogenase 2

decreases activity

perfluoro-n-nonanoic acid results in decreased activity of HSD11B2 protein

NCBI chr19:50,307,569...50,312,812
Ensembl chr19:33,397,656...33,402,899

G

hydroxysteroid (17-beta) dehydrogenase 13

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HSD17B13 mRNA

NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166

G

hydroxysteroid (17-beta) dehydrogenase 3

multiple interactions
decreases expression

[perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in decreased expression of HSD17B3 mRNA
perfluoro-n-nonanoic acid results in decreased expression of HSD17B3 mRNA; perfluoro-n-nonanoic acid results in decreased expression of HSD17B3 protein

PMID:25588985 PMID:30294798

NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,027,229...1,058,554

G

hydroxysteroid (17-beta) dehydrogenase 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HSD17B6 mRNA

NCBI chr 7:831,407...850,950
Ensembl chr 7:422,480...442,425

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

decreases expression
decreases activity

perfluoro-n-nonanoic acid results in decreased expression of HSD3B1 mRNA
perfluoro-n-nonanoic acid results in decreased expression of HSD3B1 mRNA; perfluoro-n-nonanoic acid results in decreased expression of HSD3B1 protein
perfluoro-n-nonanoic acid results in decreased activity of HSD3B1 protein

PMID:30294798 PMID:32588087 PMID:36122607

NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999

G

hydroxysteroid dehydrogenase like 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of HSDL2 mRNA

NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:74,443,872...74,479,839

G

heat shock protein family A (Hsp70) member 13

increases expression

perfluoro-n-nonanoic acid results in increased expression of HSPA13 mRNA

NCBI chr11:27,862,717...27,876,898
Ensembl chr11:14,373,275...14,389,895

G

HSPB1 associated protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of HSPBAP1 mRNA

NCBI chr11:78,445,376...78,500,034
Ensembl chr11:64,940,091...64,994,756

G

heparan sulfate proteoglycan 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HSPG2 mRNA

NCBI chr 5:154,960,818...155,061,971
Ensembl chr 5:149,677,476...149,778,594

G

isoleucyl-tRNA synthetase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IARS1 mRNA

NCBI chr17:15,147,357...15,193,716
Ensembl chr17:14,940,924...14,987,237

G

intercellular adhesion molecule 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ICAM1 mRNA

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438

G

inhibitor of DNA binding 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ID1 mRNA

NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:141,211,267...141,212,419

G

isocitrate dehydrogenase (NADP(+)) 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IDH2 mRNA

NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IDH3B mRNA

NCBI chr 3:137,934,971...137,940,275
Ensembl chr 3:117,481,845...117,486,982

G

isopentenyl-diphosphate delta isomerase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IDI1 mRNA

NCBI chr17:66,539,761...66,547,524
Ensembl chr17:61,629,594...61,637,357

G

immediate early response 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IER3 mRNA

NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,928,378...2,929,583

G

immediate early response 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IER5 mRNA

NCBI chr13:69,820,450...69,822,542
Ensembl chr13:67,270,135...67,272,227

G

interferon induced transmembrane protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IFITM2 mRNA

NCBI chr 1:205,481,168...205,482,348
Ensembl chr 1:196,051,537...196,052,741

G

interferon gamma

decreases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of IFNG protein
[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased abundance of IFNG protein

PMID:19878704 PMID:36270329

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375

G

interferon, lambda 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IFNL3 mRNA

NCBI chr 1:92,941,988...92,943,628
Ensembl chr 1:83,814,564...83,816,096

G

interferon-related developmental regulator 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IFRD1 mRNA

NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:57,269,384...57,288,990

G

interferon-related developmental regulator 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of IFRD2 mRNA

NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:108,260,969...108,266,194

G

intraflagellar transport 20

increases expression

perfluoro-n-nonanoic acid results in increased expression of IFT20 mRNA

NCBI chr10:63,930,629...63,936,174
Ensembl chr10:63,432,633...63,438,124

G

insulin-like growth factor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IGF1 mRNA

NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IGFBP1 mRNA

NCBI chr14:86,261,277...86,266,344
Ensembl chr14:82,047,415...82,052,482

G

insulin-like growth factor binding protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of IGFBP3 mRNA

NCBI chr14:86,270,208...86,277,944
Ensembl chr14:82,056,347...82,064,083

G

interleukin 10

decreases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of IL10 protein
gadolinium chloride inhibits the reaction [perfluoro-n-nonanoic acid results in decreased expression of IL10 protein]

PMID:19878704 PMID:22648072

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313

G

interleukin 15 receptor subunit alpha

increases expression

perfluoro-n-nonanoic acid results in increased expression of IL15RA mRNA

NCBI chr17:71,712,141...71,742,072
Ensembl chr17:66,802,334...66,832,278

G

interleukin 17 receptor B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IL17RB mRNA

NCBI chr16:5,186,961...5,200,657
Ensembl chr16:5,180,432...5,194,125

G

interleukin 18

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IL18 mRNA

NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 18 receptor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IL18R1 mRNA

NCBI chr 9:50,223,274...50,257,370
Ensembl chr 9:42,727,869...42,760,715

G

interleukin 1 beta

multiple interactions
increases expression
increases secretion

gadolinium chloride inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of IL1B protein]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]]
perfluoro-n-nonanoic acid results in increased secretion of IL1B protein

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor-like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IL1RL1 mRNA

NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:42,697,192...42,727,256

G

interleukin 2

decreases secretion

perfluoro-n-nonanoic acid results in decreased secretion of IL2 protein

NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 20 receptor subunit beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of IL20RB mRNA

NCBI chr 8:109,858,108...109,896,066
Ensembl chr 8:100,980,383...101,009,942

G

interleukin 22 receptor subunit alpha 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IL22RA1 mRNA

NCBI chr 5:153,245,067...153,269,865
Ensembl chr 5:147,961,349...147,986,296

G

interleukin 27

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IL27 mRNA

NCBI chr 1:190,603,684...190,609,292
Ensembl chr 1:181,173,372...181,178,582

G

interleukin 4

increases secretion

perfluoro-n-nonanoic acid results in increased secretion of IL4 protein

NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750

G

interleukin 6

increases expression
multiple interactions
affects expression

perfluoro-n-nonanoic acid results in increased expression of IL6 protein
[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in increased abundance of IL6 protein
perfluoro-n-nonanoic acid affects the expression of IL6 protein

PMID:19878704 PMID:22648072 PMID:36270329

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

inner centromere protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INCENP mRNA

NCBI chr 1:215,945,558...216,017,247
Ensembl chr 1:206,523,380...206,553,265

G

inhibin subunit beta B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INHBB mRNA; perfluoro-n-nonanoic acid results in decreased expression of INHBB protein

NCBI chr13:33,083,671...33,089,373
Ensembl chr13:30,530,860...30,537,832

G

inhibin subunit beta C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INHBC mRNA

NCBI chr 7:65,069,450...65,082,919
Ensembl chr 7:63,184,142...63,197,630

G

inhibin subunit beta E

increases expression

perfluoro-n-nonanoic acid results in increased expression of INHBE mRNA

NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:63,176,219...63,179,172

G

INO80 complex subunit E

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INO80E mRNA

NCBI chr 1:190,891,315...190,902,902
Ensembl chr 1:181,461,408...181,472,469

G

inositol polyphosphate-5-phosphatase B

increases expression

perfluoro-n-nonanoic acid results in increased expression of INPP5B mRNA

NCBI chr 5:142,281,454...142,345,993
Ensembl chr 5:136,996,686...137,061,315

G

inositol polyphosphate phosphatase-like 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INPPL1 mRNA

NCBI chr 1:165,595,047...165,609,503
Ensembl chr 1:156,183,059...156,197,500

G

insulin induced gene 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INSIG1 mRNA

NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952

G

integrator complex subunit 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INTS7 mRNA

NCBI chr13:105,686,208...105,739,609
Ensembl chr13:103,155,090...103,208,592

G

importin 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of IPO4 mRNA

NCBI chr15:33,087,321...33,097,241
Ensembl chr15:29,117,365...29,127,285

G

IQ motif containing B1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IQCB1 mRNA

NCBI chr11:77,410,986...77,465,540
Ensembl chr11:63,905,590...63,960,093

G

interleukin-1 receptor-associated kinase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of IRAK2 mRNA

NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:146,786,100...146,842,602

G

interferon regulatory factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IRF1 mRNA

NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166

G

interferon regulatory factor 2 binding protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IRF2BP1 mRNA

NCBI chr 1:87,780,782...87,783,483
Ensembl chr 1:78,652,412...78,655,530

G

interferon regulatory factor 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IRF6 mRNA

NCBI chr13:107,200,876...107,220,083
Ensembl chr13:104,672,179...104,691,386

G

interferon regulatory factor 7

increases expression

perfluoro-n-nonanoic acid results in increased expression of IRF7 mRNA

NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:196,367,361...196,370,832

G

insulin receptor substrate 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IRS1 protein modified form

NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:83,548,944...83,606,122

G

insulin receptor substrate 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of IRS2 mRNA

NCBI chr16:85,190,310...85,214,543
Ensembl chr16:78,485,045...78,512,482

G

iroquois homeobox 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IRX4 mRNA

NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549

G

integrin subunit alpha 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ITGA2 mRNA

PMID:25812627 PMID:32588087

NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:46,523,948...46,621,481

G

integrin subunit alpha 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of ITGA5 mRNA

NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:134,478,968...134,502,837

G

integrin subunit alpha D

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ITGAD mRNA

NCBI chr 1:192,190,204...192,218,864
Ensembl chr 1:182,759,740...182,788,161

G

integrin subunit alpha L

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ITGAL mRNA

NCBI chr 1:191,348,424...191,386,228
Ensembl chr 1:181,918,183...181,955,732

G

integrin subunit beta 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ITGB7 mRNA

NCBI chr 7:135,225,962...135,243,522
Ensembl chr 7:133,347,960...133,364,876

G

integrin subunit beta 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ITGB8 mRNA

NCBI chr 6:146,267,982...146,351,245
Ensembl chr 6:140,127,203...140,208,476

G

inositol-trisphosphate 3-kinase A

increases expression

perfluoro-n-nonanoic acid results in increased expression of ITPKA mRNA

NCBI chr 3:127,179,841...127,188,405
Ensembl chr 3:106,726,036...106,734,600

G

inositol 1,4,5-trisphosphate receptor, type 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ITPR1 mRNA

NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:141,187,418...141,510,491

G

jagged canonical Notch ligand 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of JAG1 mRNA

NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:124,406,794...124,442,209

G

jumonji domain containing 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of JMJD4 mRNA

NCBI chr10:44,234,465...44,242,754
Ensembl chr10:44,234,549...44,240,065

G

junction mediating and regulatory protein, p53 cofactor

increases expression

perfluoro-n-nonanoic acid results in increased expression of JMY mRNA

NCBI chr 2:26,401,047...26,465,959
Ensembl chr 2:24,668,854...24,731,006

G

junctophilin 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of JPH1 mRNA

NCBI chr 5:6,813,553...6,920,488
Ensembl chr 5:2,030,281...2,125,284

G

JPX transcript, XIST activator

increases expression

perfluoro-n-nonanoic acid results in increased expression of JPX mRNA

NCBI chr X:68,511,491...68,665,132

G

JunB proto-oncogene, AP-1 transcription factor subunit

increases expression

perfluoro-n-nonanoic acid results in increased expression of JUNB mRNA

NCBI chr19:40,081,126...40,082,910
Ensembl chr19:23,176,294...23,178,035

G

KAT8 regulatory NSL complex subunit 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of KANSL3 mRNA

NCBI chr 9:46,058,070...46,101,643
Ensembl chr 9:38,562,177...38,605,692

G

lysine acetyltransferase 6B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KAT6B mRNA

NCBI chr15:2,688,535...2,861,443
Ensembl chr15:2,639,200...2,812,316

G

potassium inwardly-rectifying channel, subfamily J, member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KCNJ1 mRNA

NCBI chr 8:39,014,822...39,066,716
Ensembl chr 8:30,753,617...30,813,796

G

potassium inwardly-rectifying channel, subfamily J, member 16

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KCNJ16 mRNA

NCBI chr10:96,489,329...96,520,745
Ensembl chr10:95,960,725...96,021,702

G

potassium calcium-activated channel subfamily N member 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KCNN4 mRNA

NCBI chr 1:89,084,306...89,102,279
Ensembl chr 1:79,959,322...79,974,340

G

potassium voltage-gated channel subfamily Q member 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of KCNQ3 mRNA

NCBI chr 7:99,614,089...99,914,736
Ensembl chr 7:97,730,465...98,025,653

G

potassium channel tetramerization domain containing 13

increases expression

perfluoro-n-nonanoic acid results in increased expression of KCTD13 mRNA

NCBI chr 1:190,965,073...190,983,381
Ensembl chr 1:181,534,515...181,552,881

G

potassium channel tetramerization domain containing 15

increases expression

perfluoro-n-nonanoic acid results in increased expression of KCTD15 mRNA

NCBI chr 1:96,395,794...96,411,502
Ensembl chr 1:87,258,658...87,273,497

G

KDEL endoplasmic reticulum protein retention receptor 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KDELR3 mRNA

NCBI chr 7:112,959,632...112,969,858
Ensembl chr 7:111,079,218...111,101,600

G

lysine demethylase 7A

increases expression

perfluoro-n-nonanoic acid results in increased expression of KDM7A mRNA

NCBI chr 4:68,866,263...68,992,979
Ensembl chr 4:67,904,307...67,966,998

G

lysine demethylase 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KDM8 mRNA

NCBI chr 1:180,013,969...180,028,829
Ensembl chr 1:180,020,656...180,028,841

G

kinase insert domain receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KDR mRNA

NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018

G

ketohexokinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KHK mRNA

NCBI chr 6:31,165,246...31,175,779
Ensembl chr 6:25,445,300...25,455,717

G

KIAA0040 ortholog

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KIAA0040 mRNA

NCBI chr13:72,274,519...72,312,103
Ensembl chr13:72,274,552...72,312,103

G

kinesin family member 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KIF11 mRNA

NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:235,124,316...235,176,766

G

kinesin family member 14

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KIF14 mRNA

NCBI chr13:50,478,646...50,542,256
Ensembl chr13:47,927,044...47,989,164

G

kinesin family member 18B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KIF18B mRNA

NCBI chr10:88,370,520...88,392,388
Ensembl chr10:87,870,428...87,889,850

G

kinesin family member 1C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KIF1C mRNA

NCBI chr10:55,913,010...55,942,220
Ensembl chr10:55,415,900...55,443,545

G

kinesin family member 20A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KIF20A mRNA

NCBI chr18:26,504,422...26,512,908
Ensembl chr18:26,230,230...26,238,780

G

kinesin family member 20B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KIF20B mRNA

NCBI chr 1:241,840,898...241,896,451
Ensembl chr 1:232,428,371...232,483,787

G

kinesin family member 22

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KIF22 mRNA

NCBI chr 1:191,065,875...191,080,955
Ensembl chr 1:181,635,183...181,650,401

G

klotho beta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KLB mRNA

NCBI chr14:43,253,963...43,304,532
Ensembl chr14:42,899,510...42,950,799

G

kinesin light chain 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of KLC2 mRNA

NCBI chr 1:211,843,927...211,854,160
Ensembl chr 1:202,414,557...202,424,672

G

kinesin light chain 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KLC4 mRNA

NCBI chr 9:14,337,164...14,351,075
Ensembl chr 9:14,337,534...14,351,066

G

KLF transcription factor 10

increases expression

perfluoro-n-nonanoic acid results in increased expression of KLF10 mRNA

NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:69,465,619...69,473,994

G

KLF transcription factor 11

increases expression

perfluoro-n-nonanoic acid results in increased expression of KLF11 mRNA

NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550

G

KLF transcription factor 16

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KLF16 mRNA

NCBI chr 7:9,789,185...9,799,004
Ensembl chr 7:9,138,503...9,148,317

G

KLF transcription factor 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of KLF4 mRNA

NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:70,278,972...70,283,602

G

kelch-like family member 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of KLHL5 mRNA

NCBI chr14:43,497,915...43,565,833
Ensembl chr14:43,144,257...43,184,238

G

kallikrein-related peptidase 15

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KLK15 mRNA

NCBI chr 1:94,699,422...94,706,626
Ensembl chr 1:94,703,158...94,706,329
Ensembl chr 1:94,703,158...94,706,329

G

kallikrein B1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KLKB1 mRNA

NCBI chr16:53,690,180...53,714,570
Ensembl chr16:46,958,707...46,982,053

G

kynurenine 3-monooxygenase

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of KMO mRNA
perfluoro-n-nonanoic acid results in decreased expression of KMO mRNA

PMID:25812627 PMID:32588087

NCBI chr13:90,089,340...90,121,108
Ensembl chr13:87,557,286...87,588,881

G

kininogen 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KNG1 mRNA

NCBI chr11:91,317,354...91,340,148
Ensembl chr11:77,812,752...77,835,555

G

kinetochore scaffold 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KNL1 mRNA

PMID:32588087 PMID:38568856

NCBI chr 3:126,483,498...126,545,774
Ensembl chr 3:106,029,661...106,091,915

G

karyopherin subunit alpha 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KPNA2 mRNA

NCBI chr10:92,433,678...92,445,841
Ensembl chr10:91,933,951...91,946,150

G

karyopherin subunit alpha 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KPNA4 mRNA

NCBI chr 2:155,635,679...155,691,056
Ensembl chr 2:153,324,273...153,381,081

G

keratin 23

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of KRT23 mRNA

NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983

G

keratin 24

increases expression

perfluoro-n-nonanoic acid results in increased expression of KRT24 mRNA

NCBI chr10:84,232,163...84,237,299
Ensembl chr10:84,232,164...84,237,299

G

keratin 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KRT5 mRNA

PMID:32588087 PMID:38568856

NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850

G

keratin associated protein 5-8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of KRTAP5-8 mRNA

NCBI chr 1:197,446,125...197,446,817
Ensembl chr 1:197,446,125...197,446,817

G

laccase domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of LACC1 mRNA

NCBI chr15:58,799,477...58,816,840
Ensembl chr15:52,395,183...52,407,545

G

laminin subunit alpha 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of LAMA4 mRNA

NCBI chr20:43,946,898...44,087,972
Ensembl chr20:42,392,268...42,533,347

G

laminin subunit alpha 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LAMA5 mRNA

NCBI chr 3:187,647,904...187,695,974
Ensembl chr 3:167,270,296...167,318,451

G

laminin subunit beta 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LAMB3 mRNA

NCBI chr13:107,362,514...107,404,081
Ensembl chr13:104,833,873...104,875,405

G

lysosomal-associated membrane protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LAMP1 mRNA

NCBI chr16:83,058,131...83,082,843
Ensembl chr16:76,355,984...76,381,883

G

lysosomal-associated membrane protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of LAMP3 mRNA

NCBI chr11:94,657,817...94,726,451
Ensembl chr11:81,193,649...81,221,784

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of LAMTOR5 mRNA

NCBI chr 2:194,900,038...194,905,394
Ensembl chr 2:194,900,038...194,905,395

G

LIM and SH3 protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LASP1 mRNA

NCBI chr10:83,290,820...83,331,989
Ensembl chr10:82,795,137...82,943,292

G

linker for activation of T cells

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LAT mRNA

NCBI chr 1:190,367,111...190,372,515
Ensembl chr 1:180,936,534...180,941,578

G

large tumor suppressor kinase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LATS2 mRNA

NCBI chr15:35,940,632...35,992,225
Ensembl chr15:31,825,092...31,877,220

G

lipocalin 2

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of LCN2 mRNA

NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095

G

lactate dehydrogenase A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LDHA mRNA

NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:97,366,021...97,433,472

G

lactate dehydrogenase D

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LDHD mRNA

NCBI chr19:56,492,827...56,497,695
Ensembl chr19:39,573,621...39,595,575

G

low density lipoprotein receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LDLR mRNA

NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:20,270,041...20,294,580

G

LEM domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LEMD1 mRNA

NCBI chr13:43,631,705...43,697,765
Ensembl chr13:43,665,926...43,697,948

G

leukocyte receptor cluster member 9

increases expression

perfluoro-n-nonanoic acid results in increased expression of LENG9 mRNA

NCBI chr 1:70,039,099...70,041,559
Ensembl chr 1:70,035,791...70,044,509

G

leucine-rich repeat-containing G protein-coupled receptor 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LGR4 mRNA

NCBI chr 3:116,901,968...117,004,584
Ensembl chr 3:96,447,858...96,548,899

G

luteinizing hormone subunit beta

multiple interactions

[perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in decreased expression of LHB protein

NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

LHFPL tetraspan subfamily member 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of LHFPL2 mRNA

NCBI chr 2:25,281,771...25,428,128
Ensembl chr 2:25,281,901...25,427,950

G

lipoic acid synthetase

increases expression

perfluoro-n-nonanoic acid results in increased expression of LIAS mRNA

NCBI chr14:42,876,699...42,893,824
Ensembl chr14:42,876,699...42,893,783

G

DNA ligase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LIG1 mRNA

NCBI chr 1:83,243,043...83,281,707
Ensembl chr 1:74,165,842...74,204,413

G

lipase C, hepatic type

decreases activity

perfluoro-n-nonanoic acid results in decreased activity of LIPC protein

NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:71,509,635...71,635,464

G

lipase G, endothelial type

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LIPG mRNA

NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260

G

lamin B1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LMNB1 mRNA

NCBI chr18:52,373,939...52,413,284
Ensembl chr18:50,175,874...50,214,502

G

lamin B2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LMNB2 mRNA

NCBI chr 7:9,443,308...9,459,468
Ensembl chr 7:8,789,314...8,808,665

G

lon peptidase 1, mitochondrial

increases expression

perfluoro-n-nonanoic acid results in increased expression of LONP1 mRNA

NCBI chr 9:1,534,581...1,546,908
Ensembl chr 9:1,447,447...1,459,771

G

lysyl oxidase

increases expression

perfluoro-n-nonanoic acid results in increased expression of LOX mRNA

NCBI chr18:48,162,889...48,175,640
Ensembl chr18:45,967,343...46,041,477

G

lipin 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LPIN3 mRNA

NCBI chr 3:169,953,479...169,978,034
Ensembl chr 3:149,534,051...149,558,327

G

lipoprotein lipase

multiple interactions
increases expression

PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of LPL mRNA]

NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249

G

LRAT domain containing 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of LRATD2 mRNA

NCBI chr 7:94,270,753...94,276,445
Ensembl chr 7:92,362,194...92,388,189

G

leucine rich repeats and calponin homology domain containing 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of LRCH2 mRNA

NCBI chr X:111,091,728...111,174,225
Ensembl chr X:111,092,814...111,174,210

G

leucine rich repeats and calponin homology domain containing 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of LRCH3 mRNA

NCBI chr11:67,772,499...67,872,269
Ensembl chr11:67,772,506...67,872,264

G

leucine-rich alpha-2-glycoprotein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LRG1 mRNA

NCBI chr 9:1,034,691...1,036,937
Ensembl chr 9:947,516...949,813

G

LDL receptor related protein 11

affects expression

perfluoro-n-nonanoic acid affects the expression of LRP11 protein

NCBI chr 1:2,048,307...2,108,115
Ensembl chr 1:2,079,438...2,108,110

G

leucine rich repeat containing 23

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LRRC23 mRNA

NCBI chr 4:159,267,572...159,277,764
Ensembl chr 4:157,581,291...157,591,860

G

leucine rich repeat containing 31

increases expression

perfluoro-n-nonanoic acid results in increased expression of LRRC31 mRNA

NCBI chr 2:112,702,844...112,725,431
Ensembl chr 2:112,700,136...112,724,322

G

leucine rich repeat containing 37A

increases expression

perfluoro-n-nonanoic acid results in increased expression of LRRC37A3 mRNA

NCBI chr10:88,395,837...88,433,519
Ensembl chr10:88,396,663...88,433,323

G

leucine rich repeat containing 47

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LRRC47 mRNA

NCBI chr 5:169,852,926...169,862,598
Ensembl chr 5:164,570,435...164,580,174

G

leucine rich repeat containing 71

increases expression

perfluoro-n-nonanoic acid results in increased expression of LRRC71 mRNA

NCBI chr 2:173,194,792...173,207,448
Ensembl chr 2:173,194,792...173,207,448

G

leucine rich repeat containing 8 VRAC subunit D

increases expression

perfluoro-n-nonanoic acid results in increased expression of LRRC8D mRNA

NCBI chr14:4,029,971...4,134,922
Ensembl chr14:4,029,473...4,135,877

G

leucine rich repeat neuronal 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of LRRN1 mRNA

NCBI chr 4:140,476,752...140,520,210
Ensembl chr 4:140,476,324...140,518,620

G

lanosterol synthase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LSS mRNA

NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,092,774...12,118,762

G

lymphotoxin beta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LTB mRNA

NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,627,537...3,629,381

G

latent transforming growth factor beta binding protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of LTBP1 mRNA

NCBI chr 6:25,781,625...26,177,346
Ensembl chr 6:20,029,629...20,425,349

G

lumican

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of LUM mRNA

NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:32,358,614...32,365,793

G

LYR motif containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of LYRM1 mRNA

NCBI chr 1:174,284,116...174,305,053
Ensembl chr 1:174,284,602...174,305,053

G

membrane associated guanylate kinase, WW and PDZ domain containing 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of MAGI2 mRNA

NCBI chr 4:15,278,518...16,762,427
Ensembl chr 4:14,386,399...15,870,240

G

membrane associated guanylate kinase, WW and PDZ domain containing 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MAGI3 mRNA

NCBI chr 2:194,206,587...194,405,468
Ensembl chr 2:191,518,506...191,716,735

G

MAK16 homolog

increases expression

perfluoro-n-nonanoic acid results in increased expression of MAK16 mRNA

NCBI chr16:67,675,757...67,684,188
Ensembl chr16:60,972,697...60,983,243

G

mal, T-cell differentiation protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of MAL2 mRNA

NCBI chr 7:87,790,239...87,823,219
Ensembl chr 7:85,900,453...85,933,429

G

mannosidase, endo-alpha

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MANEA mRNA

NCBI chr 5:40,196,373...40,218,540
Ensembl chr 5:40,196,396...40,218,459

G

mesencephalic astrocyte-derived neurotrophic factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MANF mRNA

NCBI chr 8:116,427,053...116,430,259
Ensembl chr 8:107,548,352...107,551,438

G

mitogen-activated protein kinase kinase kinase 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MAP3K11 mRNA

NCBI chr 1:212,404,685...212,417,986
Ensembl chr 1:202,975,353...202,988,652

G

mitogen activated protein kinase kinase kinase kinase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MAP4K1 mRNA

NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493

G

MAP7 domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MAP7D1 mRNA

NCBI chr 5:138,527,944...138,552,537
Ensembl chr 5:138,527,401...138,552,499

G

mitogen activated protein kinase 14

affects expression

perfluoro-n-nonanoic acid affects the expression of MAPK14 mRNA

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589

G

microtubule-associated protein, RP/EB family, member 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of MAPRE3 mRNA

NCBI chr 6:31,233,736...31,278,626
Ensembl chr 6:25,513,800...25,558,881

G

membrane associated ring-CH-type finger 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MARCHF2 mRNA

NCBI chr 7:14,480,605...14,507,821
Ensembl chr 7:14,481,761...14,507,794

G

methionine adenosyltransferase 1A

increases expression

perfluoro-n-nonanoic acid results in increased expression of MAT1A mRNA

NCBI chr16:17,017,168...17,035,368
Ensembl chr16:16,983,022...17,001,274

G

methionine adenosyltransferase 2A

increases expression

perfluoro-n-nonanoic acid results in increased expression of MAT2A mRNA

NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:104,488,466...104,495,493

G

MYC associated zinc finger protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MAZ mRNA

NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408

G

myoglobin

increases expression

perfluoro-n-nonanoic acid results in increased expression of MB mRNA

NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:108,759,904...108,767,383

G

methyl-CpG binding domain protein 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MBD6 mRNA

NCBI chr 7:63,107,562...63,115,841
Ensembl chr 7:63,107,562...63,113,274

G

mannose binding lectin 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MBL2 mRNA

PMID:25543169 PMID:32588087

NCBI chr 1:237,429,873...237,465,567

G

muscleblind-like splicing regulator 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of MBNL2 mRNA

NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937

G

melanoma cell adhesion molecule

decreases expression
affects expression

perfluoro-n-nonanoic acid results in decreased expression of MCAM mRNA
perfluoro-n-nonanoic acid affects the expression of MCAM protein

PMID:38537583 PMID:38568856

NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571

G

methylmalonyl CoA epimerase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MCEE mRNA

NCBI chr 1:117,964,576...117,987,779
Ensembl chr 1:117,964,576...117,988,484

G

MCF.2 cell line derived transforming sequence

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MCF2 mRNA

NCBI chr X:143,444,510...143,550,839
Ensembl chr X:138,409,256...138,514,446

G

minichromosome maintenance domain containing 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of MCMDC2 mRNA

NCBI chr 5:14,071,609...14,120,435
Ensembl chr 5:9,298,101...9,338,300

G

MAPK regulated co-repressor interacting protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MCRIP1 mRNA

NCBI chr10:105,820,656...105,828,146
Ensembl chr10:105,820,656...105,828,271

G

mediator complex subunit 10

increases expression

perfluoro-n-nonanoic acid results in increased expression of MED10 mRNA

NCBI chr 1:35,298,494...35,310,163
Ensembl chr 1:33,470,066...33,475,767

G

mediator complex subunit 12L

increases expression

perfluoro-n-nonanoic acid results in increased expression of MED12L mRNA

NCBI chr 2:145,403,318...145,726,317
Ensembl chr 2:143,252,139...143,573,741

G

maternal embryonic leucine zipper kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MELK mRNA

NCBI chr 5:63,336,151...63,396,254
Ensembl chr 5:58,540,449...58,600,937

G

methionyl aminopeptidase type 1D (mitochondrial)

increases expression

perfluoro-n-nonanoic acid results in increased expression of METAP1D mRNA

NCBI chr 3:56,279,471...56,354,518
Ensembl chr 3:56,279,493...56,351,981

G

meteorin-like, glial cell differentiation regulator

increases expression

perfluoro-n-nonanoic acid results in increased expression of METRNL mRNA

NCBI chr10:107,462,148...107,476,143
Ensembl chr10:106,963,880...106,977,869

G

methyltransferase 1, tRNA methylguanosine

increases expression

perfluoro-n-nonanoic acid results in increased expression of METTL1 mRNA

NCBI chr 7:64,750,189...64,754,531
Ensembl chr 7:62,864,853...62,869,202

G

methyltransferase 4, N6-adenosine

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of METTL4 mRNA

NCBI chr 9:118,887,740...118,967,433
Ensembl chr 9:111,441,027...111,464,749

G

MFSD2 lysolipid transporter A, lysophospholipid

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MFSD2A mRNA

NCBI chr 5:140,510,933...140,525,828
Ensembl chr 5:135,225,816...135,240,690

G

major facilitator superfamily domain containing 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MFSD8 mRNA

NCBI chr 2:125,749,994...125,784,689
Ensembl chr 2:123,816,614...123,857,971

G

matrix Gla protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MGP mRNA

NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:169,766,279...169,769,667

G

microsomal glutathione S-transferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MGST2 mRNA

NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:135,693,557...135,715,828

G

microtubule associated monooxygenase, calponin and LIM domain containing 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MICAL2 mRNA

NCBI chr 1:166,345,853...166,530,575
Ensembl chr 1:166,345,859...166,471,719
Ensembl chr 1:166,345,859...166,471,719

G

MICAL-like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of MICALL1 mRNA

NCBI chr 7:112,557,192...112,587,618
Ensembl chr 7:110,676,775...110,707,177

G

MIER family member 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of MIER3 mRNA

NCBI chr 2:45,021,167...45,049,745
Ensembl chr 2:43,287,916...43,316,136

G

MINDY lysine 48 deubiquitinase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MINDY1 mRNA

NCBI chr 2:182,859,977...182,873,000
Ensembl chr 2:182,860,472...182,873,015

G

Mirlet7b host gene

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MIRLET7BHG mRNA

G

mitotic spindle positioning

increases expression

perfluoro-n-nonanoic acid results in increased expression of MISP mRNA

NCBI chr 7:10,526,980...10,537,159
Ensembl chr 7:9,870,444...9,886,541

G

mitochondrial matrix import factor 23

increases expression

perfluoro-n-nonanoic acid results in increased expression of MIX23 mRNA

NCBI chr11:78,166,038...78,186,323
Ensembl chr11:64,660,711...64,681,000

G

marker of proliferation Ki-67

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MKI67 mRNA

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762

G

MAPK interacting serine/threonine kinase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of MKNK2 mRNA

NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,039,728...9,050,827

G

mohawk homeobox

increases expression

perfluoro-n-nonanoic acid results in increased expression of MKX mRNA

NCBI chr17:55,077,073...55,156,877
Ensembl chr17:55,077,540...55,156,124

G

MLLT1, super elongation complex subunit

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MLLT1 mRNA

NCBI chr 9:1,818,204...1,863,091
Ensembl chr 9:1,731,080...1,775,970

G

MLX interacting protein-like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MLXIPL mRNA

NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112

G

metabolism of cobalamin associated C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MMACHC mRNA

NCBI chr 5:130,166,056...130,172,735
Ensembl chr 5:130,166,451...130,172,601

G

monocyte to macrophage differentiation-associated 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of MMD2 mRNA

NCBI chr12:17,075,870...17,123,255
Ensembl chr12:11,962,757...12,009,773

G

methylmalonyl-CoA mutase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MMUT mRNA

NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:19,928,727...19,957,046

G

modulator of apoptosis 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of MOAP1 mRNA

NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
Ensembl chr17:121,882,366...121,898,643

G

molybdenum cofactor sulfurase

increases expression

perfluoro-n-nonanoic acid results in increased expression of MOCOS mRNA

PMID:25812627 PMID:32588087

NCBI chr18:16,206,402...16,251,928
Ensembl chr18:15,931,654...15,977,187

G

monoacylglycerol O-acyltransferase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of MOGAT1 mRNA

NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513

G

monoacylglycerol O-acyltransferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MOGAT2 mRNA

NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756

G

monoacylglycerol O-acyltransferase 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MOGAT3 mRNA

NCBI chr12:19,668,703...19,669,420
Ensembl chr12:19,668,788...19,670,754

G

motile sperm domain containing 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MOSPD3 mRNA

NCBI chr12:19,095,203...19,100,303
Ensembl chr12:19,095,242...19,099,477

G

MPL proto-oncogene, thrombopoietin receptor

increases expression

perfluoro-n-nonanoic acid results in increased expression of MPL mRNA

NCBI chr 5:137,259,288...137,281,540
Ensembl chr 5:131,973,895...131,986,797

G

MAGUK p55 scaffold protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of MPP1 mRNA

G

myosin phosphatase Rho interacting protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MPRIP mRNA

NCBI chr10:44,453,949...44,573,843
Ensembl chr10:44,453,929...44,569,118

G

MPV17 mitochondrial inner membrane protein like 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MPV17L2 mRNA

NCBI chr16:18,680,106...18,684,212
Ensembl chr16:18,681,826...18,684,212

G

myelin protein zero-like 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MPZL2 mRNA

NCBI chr 8:54,244,920...54,256,064
Ensembl chr 8:45,348,285...45,359,298

G

mannose receptor, C type 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MRC2 mRNA

NCBI chr10:90,761,751...90,823,055
Ensembl chr10:90,261,394...90,322,856

G

mitochondrial ribosomal protein S15

increases expression

perfluoro-n-nonanoic acid results in increased expression of MRPS15 mRNA

NCBI chr 5:143,606,141...143,616,734
Ensembl chr 5:138,321,593...138,332,205

G

MRT4 homolog, ribosome maturation factor

increases expression

perfluoro-n-nonanoic acid results in increased expression of MRTO4 mRNA

NCBI chr 5:156,884,985...156,891,738
Ensembl chr 5:151,601,780...151,608,287

G

musculin

increases expression

perfluoro-n-nonanoic acid results in increased expression of MSC mRNA

NCBI chr 5:9,330,522...9,336,391
Ensembl chr 5:4,547,405...4,553,203

G

methylsterol monooxygenase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MSMO1 mRNA

NCBI chr16:29,747,113...29,764,360
Ensembl chr16:24,980,697...24,998,016

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ND3 mRNA

NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798

G

metallothionein 1, pseudogene 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MT1E mRNA

NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135

G

metallothionein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MT2A mRNA

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784

G

metastasis associated 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MTA1 mRNA

NCBI chr 6:137,999,845...138,038,696
Ensembl chr 6:132,178,853...132,217,641

G

mitochondrial fission process 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MTFP1 mRNA

NCBI chr14:83,192,013...83,195,853
Ensembl chr14:78,968,442...78,972,274

G

mitochondrial fission regulator 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MTFR2 mRNA

NCBI chr 1:16,942,814...16,958,218
Ensembl chr 1:15,070,894...15,148,832

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of MTHFD1L mRNA

NCBI chr 1:42,849,424...43,038,313
Ensembl chr 1:40,444,008...40,632,905

G

myotubularin related protein 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MTMR4 mRNA

NCBI chr10:72,890,665...72,913,598
Ensembl chr10:72,392,551...72,416,342

G

mutY DNA glycosylase

increases expression

perfluoro-n-nonanoic acid results in increased expression of MUTYH mRNA

NCBI chr 5:135,510,666...135,522,777
Ensembl chr 5:130,274,122...130,286,146

G

mevalonate diphosphate decarboxylase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MVD mRNA

NCBI chr19:67,404,911...67,414,974
Ensembl chr19:50,496,367...50,507,971

G

mevalonate kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MVK mRNA

NCBI chr12:47,802,002...47,819,503
Ensembl chr12:42,141,384...42,158,882

G

max dimerization protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of MXD1 mRNA

NCBI chr 4:120,654,731...120,678,972
Ensembl chr 4:119,097,353...119,117,751

G

MYB binding protein 1a

increases expression

perfluoro-n-nonanoic acid results in increased expression of MYBBP1A mRNA

NCBI chr10:57,555,458...57,565,819
Ensembl chr10:57,056,874...57,067,255

G

MYC proto-oncogene, bHLH transcription factor

increases expression

perfluoro-n-nonanoic acid results in increased expression of MYC mRNA

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630

G

myogenesis regulating glycosidase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MYORG mRNA

NCBI chr 5:61,452,956...61,460,500
Ensembl chr 5:56,648,643...56,664,440

G

myozenin 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of MYOZ2 mRNA

NCBI chr 2:213,826,052...213,852,778
Ensembl chr 2:211,141,463...211,168,221

G

marginal zone B and B1 cell-specific protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of MZB1 mRNA

NCBI chr18:27,513,087...27,515,148
Ensembl chr18:27,239,001...27,241,094

G

N-6 adenine-specific DNA methyltransferase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of HEMK2 mRNA

NCBI chr11:26,584,750...26,597,790
Ensembl chr11:26,584,724...26,608,248

G

nucleus accumbens associated 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NACC1 mRNA

NCBI chr19:40,373,436...40,391,351
Ensembl chr19:23,468,419...23,486,528

G

N-acetylglucosamine kinase

increases expression

perfluoro-n-nonanoic acid results in increased expression of NAGK mRNA

NCBI chr 4:117,838,761...117,846,304
Ensembl chr 4:116,281,328...116,313,137

G

N-acyl phosphatidylethanolamine phospholipase D

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NAPEPLD mRNA

NCBI chr 4:14,251,591...14,291,010
Ensembl chr 4:13,361,006...13,398,748

G

N-acetyltransferase 9

increases expression

perfluoro-n-nonanoic acid results in increased expression of NAT9 mRNA

NCBI chr10:100,422,326...100,427,510
Ensembl chr10:100,422,331...100,427,611

G

neuron navigator 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of NAV2 mRNA

NCBI chr 1:98,957,629...99,322,339
Ensembl chr 1:98,663,759...99,322,337

G

NBL1, DAN family BMP antagonist

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NBL1 mRNA

NCBI chr 5:156,601,986...156,613,182
Ensembl chr 5:151,318,754...151,338,719

G

non-SMC condensin I complex, subunit D2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NCAPD2 mRNA

NCBI chr 4:159,655,051...159,677,938
Ensembl chr 4:157,968,815...157,992,020

G

non-SMC condensin II complex, subunit D3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NCAPD3 mRNA

NCBI chr 8:33,696,214...33,765,520
Ensembl chr 8:25,437,123...25,506,373

G

neutral cholesterol ester hydrolase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of NCEH1 mRNA

NCBI chr 2:112,003,677...112,064,274
Ensembl chr 2:110,074,957...110,135,588

G

NCK adaptor protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of NCK2 mRNA

NCBI chr 9:53,206,006...53,332,417
Ensembl chr 9:45,714,883...45,840,307

G

NCK-associated protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of NCKAP1 mRNA

NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217

G

nicalin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NCLN mRNA

NCBI chr 7:8,211,978...8,221,938
Ensembl chr 7:8,211,996...8,221,934

G

nuclear receptor coactivator 7

increases expression

perfluoro-n-nonanoic acid results in increased expression of NCOA7 mRNA

NCBI chr 1:28,674,614...28,835,891
Ensembl chr 1:26,856,530...27,015,871

G

nuclear receptor co-repressor 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NCOR2 mRNA

NCBI chr12:37,127,736...37,289,612
Ensembl chr12:31,466,412...31,628,319

G

NDC80 kinetochore complex component

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NDC80 mRNA

NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:111,407,191...111,440,924

G

NDRG family member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NDRG2 mRNA

NCBI chr15:27,074,481...27,087,376
Ensembl chr15:24,600,982...24,609,626

G

NDRG family member 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of NDRG4 mRNA

NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914

G

NADH:ubiquinone oxidoreductase subunit A2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NDUFA2 mRNA

NCBI chr18:28,629,795...28,631,884
Ensembl chr18:28,355,774...28,358,076

G

NADH:ubiquinone oxidoreductase complex assembly factor 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of NDUFAF4 mRNA

NCBI chr 5:38,605,169...38,610,341
Ensembl chr 5:38,605,153...38,610,336

G

NADH:ubiquinone oxidoreductase subunit B1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NDUFB1 mRNA

NCBI chr 6:121,115,649...121,124,055

G

NADH:ubiquinone oxidoreductase subunit B3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NDUFB3 mRNA

NCBI chr 9:67,623,417...67,633,629
Ensembl chr 9:60,129,154...60,139,446

G

NADH:ubiquinone oxidoreductase subunit B6

increases expression

perfluoro-n-nonanoic acid results in increased expression of NDUFB6 mRNA

NCBI chr 5:60,196,585...60,206,152
Ensembl chr 5:55,400,543...55,410,181

G

neural EGFL like 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NELL2 mRNA

NCBI chr 7:126,343,089...126,662,903
Ensembl chr 7:126,198,851...126,733,503

G

nuclear factor of activated T-cells 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NFATC1 mRNA

NCBI chr18:76,321,386...76,430,997
Ensembl chr18:74,046,904...74,156,028

G

nuclear factor of activated T-cells 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NFATC3 mRNA

NCBI chr19:50,870,464...50,944,992
Ensembl chr19:33,960,852...34,035,150

G

NFE2 like bZIP transcription factor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NFE2L1 mRNA

NCBI chr10:82,296,824...82,309,472
Ensembl chr10:81,800,366...81,832,318

G

NFE2 like bZIP transcription factor 2

increases activity
increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased activity of NFE2L2 protein
perfluoro-n-nonanoic acid results in increased expression of NFE2L2 mRNA
NFE2L2 protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXB7 mRNA]; NFE2L2 protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXC5 mRNA]; NFE2L2 protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXD10 mRNA]

PMID:30114225 PMID:30203046 PMID:32534105 PMID:35337807

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor, interleukin 3 regulated

increases expression

perfluoro-n-nonanoic acid results in increased expression of NFIL3 mRNA

NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,280,484...12,295,858

G

NFKB inhibitor zeta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NFKBIZ mRNA

NCBI chr11:58,251,720...58,279,767
Ensembl chr11:44,782,676...44,810,723

G

NFS1 cysteine desulfurase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NFS1 mRNA

NCBI chr 3:165,097,390...165,119,730
Ensembl chr 3:144,637,309...144,659,666

G

neuroglobin

increases expression

perfluoro-n-nonanoic acid results in increased expression of NGB mRNA

NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830

G

neugrin, neurite outgrowth associated

increases expression

perfluoro-n-nonanoic acid results in increased expression of NGRN mRNA

NCBI chr 1:134,213,235...134,219,348
Ensembl chr 1:134,213,456...134,219,339

G

niban apoptosis regulator 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of NIBAN1 mRNA

NCBI chr13:66,224,219...66,377,728
Ensembl chr13:63,674,171...63,827,729

G

niban apoptosis regulator 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NIBAN2 mRNA

NCBI chr 3:36,572,356...36,621,968
Ensembl chr 3:16,174,659...16,224,293

G

nucleolar protein interacting with the FHA domain of MKI67

increases expression

perfluoro-n-nonanoic acid results in increased expression of NIFK mRNA

NCBI chr13:31,946,119...31,955,950
Ensembl chr13:29,393,286...29,405,896

G

nischarin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NISCH mRNA

NCBI chr16:6,370,809...6,407,104
Ensembl chr16:6,364,374...6,400,668

G

NK1 homeobox 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NKX1-2 mRNA

NCBI chr 1:187,386,370...187,391,252
Ensembl chr 1:187,388,711...187,391,149

G

notchless homolog 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of NLE1 mRNA

NCBI chr10:67,834,059...67,844,771
Ensembl chr10:67,834,062...67,842,658

G

NLR family, CARD domain containing 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NLRC5 mRNA

NCBI chr19:10,483,601...10,587,223
Ensembl chr19:10,477,628...10,562,121

G

N-myc (and STAT) interactor

increases expression

perfluoro-n-nonanoic acid results in increased expression of NMI mRNA

NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:36,415,607...36,439,498

G

neuromedin U

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NMU mRNA

NCBI chr14:32,198,789...32,226,397
Ensembl chr14:31,844,728...31,872,192

G

nicotinamide N-methyltransferase

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of NNMT mRNA

NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:48,933,598...48,946,655

G

nicotinamide nucleotide transhydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NNT mRNA

NCBI chr 2:53,144,157...53,237,857
Ensembl chr 2:51,411,413...51,504,823

G

NIN1 (RPN12) binding protein 1 homolog

increases expression

perfluoro-n-nonanoic acid results in increased expression of NOB1 mRNA

NCBI chr19:35,322,803...35,335,354
Ensembl chr19:35,322,669...35,346,815

G

nucleolar protein 6

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of NOL6 mRNA
perfluoro-n-nonanoic acid results in decreased expression of NOL6 mRNA

PMID:25812627 PMID:32588087

NCBI chr 5:56,259,919...56,270,540
Ensembl chr 5:56,260,830...56,270,336

G

nucleolar protein 7

increases expression

perfluoro-n-nonanoic acid results in increased expression of NOL7 mRNA

NCBI chr17:21,303,650...21,306,924
Ensembl chr17:21,302,624...21,307,431

G

NOP16 nucleolar protein

increases expression

perfluoro-n-nonanoic acid results in increased expression of NOP16 mRNA

NCBI chr17:10,028,058...10,032,975
Ensembl chr17:10,022,932...10,027,867

G

NOP2 nucleolar protein

increases expression

perfluoro-n-nonanoic acid results in increased expression of NOP2 mRNA

NCBI chr 4:159,618,894...159,630,697
Ensembl chr 4:157,932,716...157,944,459

G

NOP53 ribosome biogenesis factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLTSCR2 mRNA

NCBI chr 1:85,757,271...85,765,089
Ensembl chr 1:76,629,069...76,636,902

G

NOP56 ribonucleoprotein

increases expression

perfluoro-n-nonanoic acid results in increased expression of NOP56 mRNA

NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841

G

NOP protein chaperone 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of NOPCHAP1 mRNA

NCBI chr 7:20,353,626...20,359,685
Ensembl chr 7:20,353,634...20,359,690

G

nitric oxide synthase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of NOS2 mRNA

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210

G

NADPH oxidase 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of NOX3 mRNA

NCBI chr 1:44,238,012...44,302,851
Ensembl chr 1:44,236,992...44,302,851

G

NAD(P)H quinone dehydrogenase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of NQO1 mRNA

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 0, group B, member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NR0B2 mRNA

NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:145,779,294...145,782,609

G

nuclear receptor subfamily 1, group D, member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of NR1D1 mRNA

NCBI chr10:84,224,599...84,231,812
Ensembl chr10:83,728,318...83,735,705

G

nuclear receptor subfamily 1, group H, member 3

multiple interactions
decreases expression
increases expression

PPARA gene mutant form promotes the reaction [perfluoro-n-nonanoic acid results in increased expression of NR1H3 mRNA]
perfluoro-n-nonanoic acid results in decreased expression of NR1H3 protein

PMID:25949234 PMID:26056853

NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722

G

nuclear receptor subfamily 1, group I, member 2

increases activity
multiple interactions

perfluoro-n-nonanoic acid results in increased activity of NR1I2 protein
[perfluoro-n-nonanoic acid co-treated with perfluorooctanoic acid] results in increased activity of NR1I2 protein; [perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid] results in increased activity of NR1I2 protein

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

increases activity

perfluoro-n-nonanoic acid results in increased activity of NR1I3 protein

NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906

G

nuclear receptor 2C2-associated protein

increases expression

perfluoro-n-nonanoic acid results in increased expression of NR2C2AP mRNA

NCBI chr16:19,288,454...19,290,940
Ensembl chr16:19,288,454...19,290,719

G

neuronal cell adhesion molecule

increases expression

perfluoro-n-nonanoic acid results in increased expression of NRCAM mRNA

NCBI chr 6:67,129,723...67,425,510
Ensembl chr 6:61,329,863...61,702,992

G

NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NSDHL mRNA

NCBI chr X:155,817,301...155,848,224
Ensembl chr X:150,775,080...150,807,142

G

neutral sphingomyelinase activation associated factor

increases expression

perfluoro-n-nonanoic acid results in increased expression of NSMAF mRNA

NCBI chr 5:19,517,795...19,578,773
Ensembl chr 5:19,518,348...19,577,627

G

NOP2/Sun RNA methyltransferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NSUN2 mRNA

NCBI chr 1:35,490,583...35,514,839
Ensembl chr 1:33,662,139...33,685,862

G

5', 3'-nucleotidase, cytosolic

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NT5C mRNA

NCBI chr10:100,739,591...100,742,276
Ensembl chr10:100,739,588...100,741,954

G

5' nucleotidase, ecto

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NT5E mRNA

NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:89,270,696...89,314,881

G

netrin 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of NTN4 mRNA

NCBI chr 7:30,073,637...30,187,407
Ensembl chr 7:28,186,611...28,300,390

G

neurotrophic receptor tyrosine kinase 2

increases phosphorylation

perfluoro-n-nonanoic acid results in increased phosphorylation of NTRK2 protein

NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136

G

NUBP iron-sulfur cluster assembly factor 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NUBP2 mRNA

NCBI chr10:13,903,224...13,906,928
Ensembl chr10:13,903,224...13,906,969

G

NudC domain containing 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NUDCD3 mRNA

NCBI chr14:80,976,330...81,059,183
Ensembl chr14:80,976,328...81,058,962

G

nudix hydrolase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NUDT1 mRNA

NCBI chr12:19,416,411...19,423,448
Ensembl chr12:14,302,694...14,305,826

G

nuclear FMR1 interacting protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NUFIP1 mRNA

NCBI chr15:51,429,518...51,460,308
Ensembl chr15:51,429,549...51,460,310

G

nuclear protein 1, transcriptional regulator

increases expression

perfluoro-n-nonanoic acid results in increased expression of NUPR1 mRNA

NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:181,213,368...181,215,281

G

nucleolar and spindle associated protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NUSAP1 mRNA

NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:106,603,289...106,633,624

G

neurexophilin 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of NXPH4 mRNA

NCBI chr 7:65,253,043...65,261,864
Ensembl chr 7:63,367,761...63,376,579

G

odorant binding protein 2A

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of OBP2A mRNA

NCBI chr 3:8,505,963...8,509,269
Ensembl chr 3:8,505,990...8,509,269

G

outer dynein arm docking complex subunit 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ODAD2 mRNA

NCBI chr17:55,216,877...55,409,872
Ensembl chr17:55,218,991...55,409,399

G

ornithine decarboxylase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ODC1 mRNA

NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:40,329,964...40,336,440

G

outer dense fiber of sperm tails 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ODF2 mRNA

NCBI chr 3:33,557,738...33,605,076
Ensembl chr 3:13,161,494...13,206,985

G

opioid growth factor receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of OGFR mRNA

NCBI chr 3:167,703,173...167,709,459
Ensembl chr 3:167,702,695...167,709,473

G

opiorphin prepropeptide

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of OPRPN mRNA

NCBI chr14:19,702,535...19,717,550
Ensembl chr14:19,702,535...19,717,550

G

olfactory receptor family 51 subfamily Q member 1D

increases expression

perfluoro-n-nonanoic acid results in increased expression of OR51Q1 mRNA

NCBI chr 1:167,838,348...167,839,313
Ensembl chr 1:158,426,462...158,427,427

G

ORAI calcium release-activated calcium modulator 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ORAI3 mRNA

NCBI chr 1:191,811,671...191,816,530
Ensembl chr 1:182,344,293...182,386,052

G

oxysterol binding protein-like 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of OSBPL5 mRNA

NCBI chr 1:198,862,071...198,916,469
Ensembl chr 1:198,862,055...198,916,469

G

ornithine transcarbamylase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of OTC mRNA

NCBI chr X:15,126,358...15,202,473
Ensembl chr X:12,453,834...12,566,918

G

otopetrin 1

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of OTOP1 mRNA

NCBI chr14:76,717,330...76,744,785
Ensembl chr14:72,503,592...72,532,497

G

purinergic receptor P2X 7

increases expression

perfluoro-n-nonanoic acid results in increased expression of P2RX7 mRNA

NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619

G

phosphofurin acidic cluster sorting protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PACS2 mRNA

NCBI chr 6:132,096,992...132,156,702
Ensembl chr 6:132,096,901...132,154,583

G

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PAFAH1B3 mRNA

NCBI chr 1:80,881,263...80,883,789
Ensembl chr 1:80,881,309...80,883,893

G

phenylalanine hydroxylase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PAH mRNA

NCBI chr 7:23,793,096...23,885,631
Ensembl chr 7:21,933,179...21,998,130

G

poly(A) binding protein interacting protein 2B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PAIP2B mRNA

NCBI chr 4:116,292,001...116,323,387
Ensembl chr 4:116,292,020...116,323,379

G

PAK1 interacting protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of PAK1IP1 mRNA

NCBI chr17:23,742,217...23,753,325
Ensembl chr17:23,741,414...23,753,324

G

pantothenate kinase 1

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of PANK1 mRNA
PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of PANK1 mRNA]

NCBI chr 1:241,737,371...241,808,126
Ensembl chr 1:232,328,430...232,396,829

G

pantothenate kinase 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PANK3 mRNA

NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955

G

progestin and adipoQ receptor family member 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PAQR9 mRNA

NCBI chr 8:104,993,884...104,996,180

G

poly (ADP-ribose) polymerase family, member 12

increases expression

perfluoro-n-nonanoic acid results in increased expression of PARP12 mRNA

NCBI chr 4:67,826,548...67,885,356
Ensembl chr 4:67,839,237...67,883,685

G

paired box 8

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of PAX8 mRNA
perfluoro-n-nonanoic acid results in decreased expression of PAX8 mRNA

PMID:22071372 PMID:25812627

NCBI chr 3:27,584,000...27,641,094
Ensembl chr 3:7,185,723...7,242,363

G

PDZ binding kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PBK mRNA

NCBI chr15:44,198,506...44,209,572
Ensembl chr15:40,023,002...40,034,014

G

phenazine biosynthesis-like protein domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PBLD mRNA

NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614

G

PBX homeobox interacting protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PBXIP1 mRNA

NCBI chr 2:177,154,056...177,167,810
Ensembl chr 2:174,856,397...174,868,919

G

pterin-4 alpha-carbinolamine dehydratase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of PCBD2 mRNA

NCBI chr17:8,850,349...8,902,420
Ensembl chr17:8,845,084...8,910,539

G

protocadherin 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of PCDH1 mRNA

NCBI chr18:30,011,692...30,039,679
Ensembl chr18:30,013,185...30,039,318

G

protocadherin alpha 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of PCDHA1 mRNA

Ensembl chr18:28,581,225...28,846,211

G

protocadherin alpha 11

increases expression

perfluoro-n-nonanoic acid results in increased expression of PCDHA11 mRNA

Ensembl chr18:28,581,225...28,846,211

G

protocadherin alpha subfamily C, 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of PCDHAC2 mRNA

Ensembl chr18:28,581,225...28,846,211

G

protocadherin beta 22

increases expression

perfluoro-n-nonanoic acid results in increased expression of PCDHB15 mRNA

NCBI chr18:29,497,038...29,503,142
Ensembl chr18:29,223,149...29,225,536

G

protocadherin gamma subfamily C, 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PCDHGC3 mRNA

NCBI chr18:29,633,016...29,667,865
Ensembl chr18:29,493,954...29,667,868

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

increases expression

perfluoro-n-nonanoic acid results in increased expression of PCK2 mRNA

NCBI chr15:32,997,853...33,006,691
Ensembl chr15:29,027,894...29,037,283

G

proliferating cell nuclear antigen

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PCNA protein

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995

G

proprotein convertase subtilisin/kexin type 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PCSK4 mRNA

NCBI chr 7:9,381,366...9,389,589
Ensembl chr 7:9,381,361...9,389,585

G

proprotein convertase subtilisin/kexin type 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PCSK5 mRNA

NCBI chr 1:224,263,823...224,694,350
Ensembl chr 1:214,837,927...215,267,600

G

proprotein convertase subtilisin/kexin type 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PCSK6 mRNA

NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596

G

proprotein convertase subtilisin/kexin type 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PCSK9 mRNA

NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:121,211,278...121,233,688

G

phosphatidylcholine transfer protein

increases expression

perfluoro-n-nonanoic acid results in increased expression of PCTP mRNA

PMID:25812627 PMID:28558994

NCBI chr10:75,305,999...75,351,919
Ensembl chr10:74,808,887...74,849,867

G

prenylcysteine oxidase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PCYOX1 mRNA

NCBI chr 4:120,389,545...120,400,382
Ensembl chr 4:118,830,638...118,842,951

G

phosphate cytidylyltransferase 2, ethanolamine

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PCYT2 mRNA

NCBI chr10:105,888,769...105,896,182
Ensembl chr10:105,888,775...105,896,172

G

phosphodiesterase 11A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PDE11A mRNA

NCBI chr 3:81,320,822...81,704,397
Ensembl chr 3:60,913,562...61,297,158

G

phosphodiesterase 1C

increases expression

perfluoro-n-nonanoic acid results in increased expression of PDE1C mRNA

NCBI chr 4:86,629,074...87,108,147
Ensembl chr 4:85,300,858...85,863,219

G

phosphodiesterase 3B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PDE3B mRNA

NCBI chr 1:178,041,207...178,204,503
Ensembl chr 1:168,607,022...168,769,334

G

phosphodiesterase 7B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PDE7B mRNA

NCBI chr 1:16,994,072...17,312,828
Ensembl chr 1:15,182,704...15,492,900

G

platelet derived growth factor subunit A

increases expression

perfluoro-n-nonanoic acid results in increased expression of PDGFA mRNA

NCBI chr12:20,759,366...20,780,337
Ensembl chr12:15,645,541...15,666,497

G

platelet derived growth factor D

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PDGFD mRNA

NCBI chr 8:11,773,335...12,007,277
Ensembl chr 8:3,488,423...3,722,395

G

protein disulfide isomerase family A, member 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PDIA4 mRNA

NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:76,803,198...76,822,107

G

pyruvate dehydrogenase kinase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PDK1 protein modified form

NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:56,705,871...56,733,038

G

pyruvate dehydrogenase kinase 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PDK3 mRNA

NCBI chr X:62,480,535...62,547,371
Ensembl chr X:58,486,554...58,553,557

G

pyruvate dehydrogenase kinase 4

affects expression
multiple interactions
increases expression

perfluoro-n-nonanoic acid affects the expression of PDK4 mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of PDK4 mRNA; PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PDK4 mRNA]

PMID:23567314 PMID:25689681 PMID:32588087 PMID:33483757

NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:33,589,799...33,601,850

G

pancreatic and duodenal homeobox 1

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of PDX1 mRNA
PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of PDX1 mRNA]

NCBI chr12:12,793,957...12,799,156
Ensembl chr12:7,757,865...7,763,064

G

PDZ domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PDZK1 mRNA

NCBI chr 2:187,064,995...187,096,348
Ensembl chr 2:184,376,161...184,407,514

G

PDZK1 interacting protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PDZK1IP1 mRNA

NCBI chr 5:133,841,586...133,859,894
Ensembl chr 5:128,618,237...128,623,131

G

paternally expressed 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of PEG3 mRNA

NCBI chr 1:67,097,874...67,124,692
Ensembl chr 1:67,097,904...67,124,671

G

period circadian regulator 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PER1 mRNA

NCBI chr10:54,299,002...54,313,804
Ensembl chr10:53,805,535...53,814,431

G

period circadian regulator 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of PER2 mRNA

NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459

G

peroxisomal biogenesis factor 11 alpha

increases expression

perfluoro-n-nonanoic acid results in increased expression of PEX11A mRNA

NCBI chr 1:143,089,410...143,096,491
Ensembl chr 1:133,680,091...133,687,172

G

prefoldin subunit 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of PFDN2 mRNA

NCBI chr13:86,305,037...86,323,008
Ensembl chr13:83,753,877...83,790,504

G

progastricsin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PGC mRNA

NCBI chr 9:20,755,002...20,763,220
Ensembl chr 9:13,257,462...13,265,682

G

peptidoglycan recognition protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PGLYRP2 mRNA

NCBI chr 7:12,069,414...12,082,437
Ensembl chr 7:11,418,880...11,427,773

G

phosphoglycerate dehydrogenase

increases expression

perfluoro-n-nonanoic acid results in increased expression of PHGDH mRNA

NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:185,906,966...185,935,944

G

PHD and ring finger domains 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PHRF1 mRNA

NCBI chr 1:196,333,663...196,366,901
Ensembl chr 1:196,333,903...196,366,892

G

protein inhibitor of activated STAT, 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PIAS3 mRNA

NCBI chr 2:186,921,384...186,930,292
Ensembl chr 2:184,232,571...184,241,480

G

phosphotyrosine interaction domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PID1 mRNA

NCBI chr 9:92,732,471...92,951,168
Ensembl chr 9:85,284,335...85,503,044

G

piercer of microtubule wall 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of PIERCE2 mRNA

NCBI chr 8:73,715,383...73,719,849
Ensembl chr 8:73,715,383...73,719,849

G

piezo-type mechanosensitive ion channel component 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PIEZO2 mRNA

NCBI chr18:56,468,449...56,844,984
Ensembl chr18:56,469,680...56,844,216

G

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PIK3C2B mRNA

NCBI chr13:47,046,866...47,107,733
Ensembl chr13:44,495,050...44,555,612

G

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PIK3C2G mRNA

NCBI chr 4:174,215,527...174,583,378
Ensembl chr 4:172,484,345...172,850,544

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PIK3CA mRNA

NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032

G

phosphoinositide-3-kinase interacting protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PIK3IP1 mRNA

NCBI chr14:82,428,315...82,440,261
Ensembl chr14:78,204,053...78,216,608

G

polycystin 1, transient receptor potential channel interacting

increases expression

perfluoro-n-nonanoic acid results in increased expression of PKD1 mRNA

NCBI chr10:14,077,733...14,125,682
Ensembl chr10:13,573,021...13,621,128

G

pyruvate kinase L/R

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PKLR mRNA

NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:174,543,039...174,551,870

G

protein kinase N1

increases expression

perfluoro-n-nonanoic acid results in increased expression of PKN1 mRNA

NCBI chr19:41,346,855...41,374,832
Ensembl chr19:24,442,122...24,470,107

G

phospholipase A2, group XIIB

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLA2G12B mRNA

NCBI chr20:27,910,620...27,931,734
Ensembl chr20:27,370,266...27,388,743

G

phospholipase A2 group IB

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLA2G1B mRNA

NCBI chr12:46,802,932...46,814,511
Ensembl chr12:41,142,200...41,153,226

G

placenta associated 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLAC8 mRNA

NCBI chr14:9,356,950...9,378,586
Ensembl chr14:9,063,048...9,074,264

G

phospholipase C, epsilon 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of PLCE1 mRNA

NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:236,244,683...236,551,438

G

phosphatidylinositol-specific phospholipase C, X domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLCXD1 mRNA

NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392

G

phospholipase D1

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of PLD1 mRNA
perfluoro-n-nonanoic acid results in decreased expression of PLD1 mRNA

PMID:25812627 PMID:32588087

NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:110,893,608...111,047,692

G

phospholipase D family, member 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLD5 mRNA

NCBI chr13:87,895,694...88,232,868
Ensembl chr13:87,896,369...88,232,868

G

phospholipase D family, member 6

increases expression

perfluoro-n-nonanoic acid results in increased expression of PLD6 mRNA

NCBI chr10:45,078,081...45,080,732
Ensembl chr10:44,577,675...44,581,077

G

plasminogen

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLG mRNA

NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:48,325,185...48,367,786

G

perilipin 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of PLIN2 mRNA

PMID:23567314 PMID:32588087

NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:101,154,411...101,242,319

G

perilipin 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of PLIN4 mRNA

NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056

G

polo-like kinase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLK1 mRNA

NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:176,716,420...176,726,400

G

polo-like kinase 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of PLK3 mRNA

NCBI chr 5:135,843,725...135,848,900
Ensembl chr 5:130,607,142...130,612,317

G

plastin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLS1 mRNA

NCBI chr 8:105,196,312...105,306,252
Ensembl chr 8:96,317,849...96,385,195

G

phospholipid transfer protein

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of PLTP mRNA

NCBI chr 3:173,994,162...174,011,982
Ensembl chr 3:153,574,825...153,592,647

G

plexin A2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLXNA2 mRNA

NCBI chr13:106,163,103...106,358,979
Ensembl chr13:106,163,103...106,358,979

G

plexin B2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLXNB2 mRNA

NCBI chr 7:120,232,276...120,258,385
Ensembl chr 7:120,232,331...120,258,330

G

plexin C1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLXNC1 mRNA

NCBI chr 7:31,276,978...31,430,823
Ensembl chr 7:29,390,048...29,543,779

G

plexin D1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PLXND1 mRNA

NCBI chr 4:150,675,377...150,715,706
Ensembl chr 4:149,002,784...149,043,244

G

phorbol-12-myristate-13-acetate-induced protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of PMAIP1 mRNA

NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429

G

PMS1 homolog 2, mismatch repair system component

increases expression

perfluoro-n-nonanoic acid results in increased expression of PMS2 mRNA

NCBI chr12:15,790,478...15,814,790
Ensembl chr12:10,676,764...10,701,066

G

partner of NOB1 homolog

increases expression

perfluoro-n-nonanoic acid results in increased expression of PNO1 mRNA

NCBI chr14:95,811,335...95,819,903
Ensembl chr14:91,609,233...91,618,324

G

purine nucleoside phosphorylase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PNP mRNA

NCBI chr15:26,644,147...26,651,808
Ensembl chr15:24,170,602...24,203,986

G

patatin-like phospholipase domain containing 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PNPLA2 mRNA

NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:196,552,723...196,557,805

G

patatin-like phospholipase domain containing 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PNPLA3 mRNA

NCBI chr 7:117,173,485...117,194,065
Ensembl chr 7:115,293,538...115,314,077

G

DNA polymerase alpha 2, accessory subunit

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of POLA2 mRNA

NCBI chr 1:212,656,500...212,680,667
Ensembl chr 1:203,203,388...203,251,348

G

RNA polymerase III subunit C

increases expression

perfluoro-n-nonanoic acid results in increased expression of POLR3C mRNA

NCBI chr 2:186,935,038...186,950,962
Ensembl chr 2:184,246,204...184,262,208

G

RNA polymerase III subunit H

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of POLR3H mRNA

NCBI chr 7:113,429,434...113,439,743
Ensembl chr 7:113,429,451...113,439,778

G

RNA polymerase mitochondrial

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of POLRMT mRNA

NCBI chr 7:9,959,532...9,969,791
Ensembl chr 7:9,959,576...9,969,791

G

proopiomelanocortin

multiple interactions

[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluoro-n-nonanoic acid] which results in decreased expression of POMC protein modified form

NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664

G

protein-O-mannose kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of POMK mRNA

NCBI chr16:66,085,569...66,101,360
Ensembl chr16:66,088,000...66,098,388

G

paraoxonase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PON1 mRNA

NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:33,294,722...33,321,360

G

paraoxonase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PON2 mRNA

NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248

G

cytochrome p450 oxidoreductase

increases expression

perfluoro-n-nonanoic acid results in increased expression of POR mRNA

PMID:23567314 PMID:32588087

NCBI chr12:26,587,674...26,655,612
Ensembl chr12:20,951,058...20,999,245

G

peroxisome proliferator activated receptor alpha

increases expression
affects binding
increases activity
decreases response to substance
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA
perfluoro-n-nonanoic acid binds to PPARA protein
perfluoro-n-nonanoic acid results in increased activity of PPARA protein
PPARA gene mutant form results in decreased susceptibility to perfluoro-n-nonanoic acid
[perfluorooctanoic acid co-treated with perfluoro-n-nonanoic acid] results in increased expression of PPARA mRNA; [PPARA gene mutant form results in increased susceptibility to perfluoro-n-nonanoic acid] which results in increased expression of AKR1B7 mRNA; [PPARA gene mutant form results in increased susceptibility to perfluoro-n-nonanoic acid] which results in increased expression of CYP2B10 mRNA; PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in decreased expression of APOC3 mRNA]; PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CD36 mRNA]; PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CIDEC mRNA]; PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PDK4 mRNA]; PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of SCD1 mRNA]; PPARA gene mutant form promotes the reaction [perfluoro-n-nonanoic acid results in increased expression of NR1H3 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXA5 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXB7 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXC5 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXD10 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of PANK1 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of PDX1 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of ZEB1 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of ZEB2 mRNA]
gadolinium chloride promotes the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]]; prolinedithiocarbamate inhibits the reaction [TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]]; TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]

PMID:19196829 PMID:19878704 PMID:22648072 PMID:23470359 PMID:24374136 More...

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor delta

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of PPARD mRNA
perfluoro-n-nonanoic acid results in decreased expression of PPARD mRNA

PMID:23567314 PMID:25812627

NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968

G

peroxisome proliferator-activated receptor gamma

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of PPARG mRNA
[perfluorooctane sulfonic acid co-treated with perfluorooctanoic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in increased expression of PPARG mRNA

PMID:19196829 PMID:19878704 PMID:28558994 PMID:39111555

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468

G

PPARG coactivator 1 alpha

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of PPARGC1A mRNA
perfluoro-n-nonanoic acid results in increased expression of PPARGC1A mRNA

PMID:23567314 PMID:32588087

NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656

G

pancreatic progenitor cell differentiation and proliferation factor

increases expression

perfluoro-n-nonanoic acid results in increased expression of PPDPF mRNA

NCBI chr 3:168,299,309...168,301,040
Ensembl chr 3:168,299,791...168,301,036

G

peptidylprolyl isomerase like 6

increases expression

perfluoro-n-nonanoic acid results in increased expression of PPIL6 mRNA

NCBI chr20:44,989,509...45,017,833
Ensembl chr20:44,988,943...45,018,340

G

protein phosphatase, Mg2+/Mn2+ dependent, 1G

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PPM1G mRNA

NCBI chr 6:30,873,531...30,893,735
Ensembl chr 6:25,153,556...25,173,761

G

protein phosphatase, Mg2+/Mn2+ dependent, 1L

increases expression

perfluoro-n-nonanoic acid results in increased expression of PPM1L mRNA

NCBI chr 2:153,566,653...153,839,434
Ensembl chr 2:153,566,653...153,839,434

G

protein phosphatase 1, regulatory subunit 12C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PPP1R12C mRNA

NCBI chr 1:69,320,240...69,343,200
Ensembl chr 1:69,320,255...69,343,200

G

protein phosphatase 1, regulatory subunit 13 like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PPP1R13L mRNA

NCBI chr 1:88,139,000...88,158,714
Ensembl chr 1:79,011,745...79,030,712

G

protein phosphatase 1, regulatory (inhibitor) subunit 14B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PPP1R14B mRNA

NCBI chr 1:213,594,416...213,596,527
Ensembl chr 1:204,163,299...204,167,319
Ensembl chr12:204,163,299...204,167,319

G

protein phosphatase 1, regulatory subunit 15B

increases expression

perfluoro-n-nonanoic acid results in increased expression of PPP1R15B mRNA

NCBI chr13:44,577,840...44,585,737
Ensembl chr13:44,577,932...44,585,737

G

protein phosphatase 1, regulatory (inhibitor) subunit 1A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PPP1R1A mRNA

NCBI chr 7:136,533,031...136,540,687
Ensembl chr 7:134,654,579...134,662,230

G

protein phosphatase 1, regulatory subunit 37

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PPP1R37 mRNA

NCBI chr 1:79,180,794...79,212,612
Ensembl chr 1:79,180,793...79,212,612

G

PPARG related coactivator 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of PPRC1 mRNA

NCBI chr 1:254,851,136...254,867,570
Ensembl chr 1:244,902,179...244,918,587

G

PR/SET domain 16

increases expression

perfluoro-n-nonanoic acid results in increased expression of PRDM16 mRNA

NCBI chr 5:170,162,275...170,486,371
Ensembl chr 5:164,880,587...165,203,601

G

prolactin

multiple interactions

[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluoro-n-nonanoic acid] which results in decreased expression of PRL protein

NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062

G

protein arginine methyltransferase 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PRMT5 mRNA

NCBI chr15:31,938,927...31,948,318
Ensembl chr15:27,968,910...27,978,296

G

pre-mRNA processing factor 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PRPF3 mRNA

NCBI chr 2:186,067,980...186,092,427
Ensembl chr 2:183,378,718...183,403,489

G

pre-mRNA processing factor 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PRPF6 mRNA

NCBI chr 3:189,084,465...189,148,705
Ensembl chr 3:168,704,299...168,774,991

G

paired related homeobox 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PRRX2 mRNA

NCBI chr 3:34,530,331...34,566,284
Ensembl chr 3:14,094,004...14,168,535

G

serine protease 23

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PRSS23 mRNA

NCBI chr 1:152,815,301...152,835,005
Ensembl chr 1:143,401,396...143,422,091

G

serine protease 36

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PRSS36 mRNA

NCBI chr 1:182,543,085...182,561,141
Ensembl chr 1:182,543,085...182,559,280

G

phosphoserine aminotransferase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of PSAT1 mRNA

NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:213,196,709...213,218,682

G

proteasome 20S subunit beta 10

increases expression

perfluoro-n-nonanoic acid results in increased expression of PSMB10 mRNA

NCBI chr19:50,740,808...50,743,292
Ensembl chr19:33,827,229...33,833,626

G

proteasome activator subunit 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of PSME2 mRNA

NCBI chr15:33,048,452...33,053,055
Ensembl chr15:29,078,500...29,082,946

G

phosphoserine phosphatase

increases expression

perfluoro-n-nonanoic acid results in increased expression of PSPH mRNA

NCBI chr12:32,527,091...32,541,182
Ensembl chr12:26,883,133...26,905,074

G

polypyrimidine tract binding protein 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PTBP3 mRNA

NCBI chr 5:74,313,367...74,399,439
Ensembl chr 5:74,315,101...74,399,791

G

parathyroid hormone 1 receptor

increases expression

perfluoro-n-nonanoic acid results in increased expression of PTH1R mRNA

NCBI chr 8:119,572,295...119,597,405
Ensembl chr 8:110,697,485...110,719,729

G

parathymosin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PTMS mRNA

NCBI chr 4:159,408,647...159,412,837
Ensembl chr 4:157,722,386...157,727,009

G

protein tyrosine phosphatase, non-receptor type 11

multiple interactions

perfluoro-n-nonanoic acid binds to and results in decreased activity of PTPN11 protein

NCBI chr12:41,026,079...41,085,577
Ensembl chr12:35,383,144...35,424,925

G

protein tyrosine phosphatase, non-receptor type 23

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PTPN23 mRNA

NCBI chr 8:119,239,213...119,261,675
Ensembl chr 8:110,360,804...110,383,271

G

protein tyrosine phosphatase, non-receptor type 9

increases expression

perfluoro-n-nonanoic acid results in increased expression of PTPN9 mRNA

NCBI chr 8:57,391,290...57,472,352
Ensembl chr 8:57,391,259...57,470,952

G

pentraxin 3

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of PTX3 mRNA
perfluoro-n-nonanoic acid results in decreased expression of PTX3 mRNA

PMID:32588087 PMID:38568856

NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323

G

pumilio RNA-binding family member 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of PUM3 mRNA

NCBI chr 1:234,483,482...234,527,718
Ensembl chr 1:225,074,333...225,114,025

G

pseudouridine synthase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of PUS1 mRNA

NCBI chr12:51,539,659...51,548,975
Ensembl chr12:45,880,440...45,889,196

G

pseudouridine synthase 7

increases expression

perfluoro-n-nonanoic acid results in increased expression of PUS7 mRNA

NCBI chr 4:12,252,553...12,293,547
Ensembl chr 4:11,360,188...11,401,172

G

PX domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of PXDC1 mRNA

NCBI chr17:30,275,998...30,304,971
Ensembl chr17:30,276,377...30,304,973

G

PX domain containing serine/threonine kinase like

increases expression

perfluoro-n-nonanoic acid results in increased expression of PXK mRNA

NCBI chr15:16,759,857...16,828,452
Ensembl chr15:16,759,862...16,828,444

G

peroxisomal membrane protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PXMP2 mRNA

NCBI chr12:46,394,051...46,404,561
Ensembl chr12:46,394,193...46,404,557

G

peroxisomal membrane protein 4

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of PXMP4 mRNA
perfluoro-n-nonanoic acid results in increased expression of PXMP4 mRNA

PMID:25543169 PMID:32588087

NCBI chr 3:163,553,582...163,570,829
Ensembl chr 3:143,093,018...143,110,651

G

glycogen phosphorylase B

increases expression

perfluoro-n-nonanoic acid results in increased expression of PYGB mRNA

NCBI chr 3:160,072,141...160,118,930
Ensembl chr 3:139,611,749...139,663,553

G

glycogen phosphorylase, muscle associated

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of PYGM mRNA

NCBI chr 1:213,119,805...213,134,622
Ensembl chr 1:203,690,533...203,705,368

G

pyridine nucleotide-disulphide oxidoreductase domain 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of PYROXD1 mRNA

NCBI chr 4:175,292,124...175,311,143
Ensembl chr 4:175,292,177...175,308,689

G

glutaminyl-tRNA synthetase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of QARS1 mRNA

NCBI chr 8:118,086,243...118,094,274
Ensembl chr 8:109,207,705...109,215,739

G

glutaminyl-tRNA amidotransferase subunit QRSL1

increases expression

perfluoro-n-nonanoic acid results in increased expression of QRSL1 mRNA

NCBI chr20:47,357,206...47,382,160
Ensembl chr20:47,357,216...47,382,135

G

quiescin sulfhydryl oxidase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of QSOX2 mRNA

NCBI chr 3:29,433,091...29,462,739
Ensembl chr 3:9,034,994...9,064,664

G

RAB11 family interacting protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of RAB11FIP2 mRNA

NCBI chr 1:268,908,825...269,080,691
Ensembl chr 1:258,923,873...259,093,752

G

RAB11 family interacting protein 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RAB11FIP3 mRNA

NCBI chr10:15,002,650...15,086,382
Ensembl chr10:15,002,926...15,118,479

G

RAB11 family interacting protein 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RAB11FIP4 mRNA

NCBI chr10:64,550,109...64,658,123
Ensembl chr10:64,550,177...64,654,759

G

RAB26, member RAS oncogene family

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RAB26 mRNA

NCBI chr10:13,553,395...13,558,063
Ensembl chr10:13,553,395...13,558,030

G

RAB3A interacting protein-like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of RAB3IL1 mRNA

NCBI chr 1:216,071,043...216,107,609
Ensembl chr 1:206,646,155...206,679,972

G

RAB9A, member RAS oncogene family

increases expression

perfluoro-n-nonanoic acid results in increased expression of RAB9 mRNA

NCBI chr X:27,955,552...28,009,870
Ensembl chr X:27,952,204...28,001,622

G

RAB, member RAS oncogene family-like 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RABL6 mRNA

PMID:25812627 PMID:38568856

NCBI chr 3:28,800,802...28,826,722
Ensembl chr 3:8,402,672...8,428,611

G

Rap associating with DIL domain

increases expression
affects methylation

perfluoro-n-nonanoic acid results in increased expression of RADIL mRNA
perfluoro-n-nonanoic acid affects the methylation of RADIL gene

PMID:25812627 PMID:35266797

NCBI chr12:12,024,395...12,088,540
Ensembl chr12:12,024,395...12,088,540

G

recombination activating 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RAG1 mRNA

PMID:36326898 PMID:38549690

NCBI chr 3:108,372,087...108,383,184
Ensembl chr 3:87,917,004...87,928,291

G

recombination activating 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RAG2 mRNA

PMID:36326898 PMID:38549690

NCBI chr 3:108,357,399...108,367,186
Ensembl chr 3:87,902,238...87,911,066

G

RAN binding protein 3-like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RANBP3L mRNA

NCBI chr 2:59,785,070...59,840,338
Ensembl chr 2:58,058,263...58,113,172

G

Rap guanine nucleotide exchange factor 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of RAPGEF4 mRNA

NCBI chr 3:77,217,024...77,509,933
Ensembl chr 3:56,809,270...57,102,316

G

retinoic acid receptor responder 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of RARRES1 mRNA

PMID:28558994 PMID:32588087

NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:151,749,715...151,783,978

G

ras related dexamethasone induced 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of RASD1 mRNA

NCBI chr10:45,265,975...45,275,279
Ensembl chr10:44,766,455...44,768,186

G

RASD family, member 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of RASD2 mRNA

NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016

G

RAS guanyl releasing protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RASGRP2 mRNA

NCBI chr 1:203,705,777...203,722,993
Ensembl chr 1:203,707,481...203,722,993

G

RAS-like family 11 member A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RASL11A mRNA

NCBI chr12:8,258,148...8,260,909
Ensembl chr12:8,258,159...8,262,576

G

ribonucleoprotein, PTB-binding 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RAVER1 mRNA

NCBI chr 8:19,610,464...19,629,188
Ensembl chr 8:19,610,466...19,629,152

G

RB binding protein 4, chromatin remodeling factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RBBP4 mRNA

NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284
Ensembl chr 2:141,638,421...141,675,284

G

RANBP2-type and C3HC4-type zinc finger containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of RBCK1 mRNA

NCBI chr 3:161,249,389...161,266,321
Ensembl chr 3:140,789,080...140,806,005

G

RNA binding motif protein 14

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RBM14 mRNA

NCBI chr 1:211,476,298...211,535,077
Ensembl chr 1:202,078,287...202,105,665
Ensembl chr 1:202,078,287...202,105,665

G

RNA binding motif protein 41

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RBM41 mRNA

NCBI chr X:103,605,732...103,660,381
Ensembl chr X:103,608,585...103,660,381

G

regulator of calcineurin 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of RCAN2 mRNA

NCBI chr 9:24,456,861...24,674,234
Ensembl chr 9:16,959,480...17,174,856

G

regulator of chromosome condensation 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of RCC2 mRNA

NCBI chr 5:158,277,476...158,300,294
Ensembl chr 5:152,993,665...153,017,205

G

retinol dehydrogenase 16

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RDH16 mRNA

NCBI chr 7:65,499,763...65,510,304
Ensembl chr 7:63,597,536...63,624,124

G

reversion-inducing-cysteine-rich protein with kazal motifs

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RECK mRNA

NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:58,102,981...58,169,502

G

RecQ like helicase 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RECQL4 mRNA

NCBI chr 7:110,304,092...110,311,426
Ensembl chr 7:108,423,455...108,430,619

G

regenerating family member 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of REG4 mRNA

NCBI chr 2:185,818,946...185,833,252
Ensembl chr 2:185,821,210...185,833,353

G

RELB proto-oncogene, NF-kB subunit

increases expression

perfluoro-n-nonanoic acid results in increased expression of RELB mRNA

NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:79,257,725...79,285,507

G

resistin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RETN protein

NCBI chr12:6,508,653...6,511,115
Ensembl chr12:1,710,881...1,712,620

G

retinol saturase

increases expression

perfluoro-n-nonanoic acid results in increased expression of RETSAT mRNA

NCBI chr 4:106,211,459...106,220,222
Ensembl chr 4:104,653,155...104,668,310

G

RNA exonuclease 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of REXO2 mRNA

NCBI chr 8:57,708,420...57,720,142
Ensembl chr 8:48,811,900...48,823,622

G

REX4 homolog, 3'-5' exonuclease

increases expression

perfluoro-n-nonanoic acid results in increased expression of REXO4 mRNA

NCBI chr 3:30,678,729...30,692,376
Ensembl chr 3:10,280,654...10,290,996

G

raftlin lipid raft linker 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RFTN1 mRNA

NCBI chr 9:18,302,143...18,499,819
Ensembl chr 9:10,804,611...11,002,084

G

regulator of cell cycle

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RGCC mRNA

NCBI chr15:61,071,574...61,084,408
Ensembl chr15:54,662,483...54,681,141

G

regulator of G-protein signaling 6

increases expression

perfluoro-n-nonanoic acid results in increased expression of RGS6 mRNA

NCBI chr 6:107,875,883...108,527,472
Ensembl chr 6:102,264,447...102,824,753

G

rhomboid domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of RHBDD1 mRNA

NCBI chr 9:91,076,786...91,196,719
Ensembl chr 9:83,630,063...83,748,689

G

rhomboid 5 homolog 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of RHBDF2 mRNA

NCBI chr10:101,833,157...101,860,283
Ensembl chr10:101,833,157...101,860,283

G

RIB43A domain with coiled-coils 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of RIBC2 mRNA

NCBI chr 7:116,242,863...116,257,868
Ensembl chr 7:116,242,863...116,257,863

G

ring finger protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RING1 mRNA

NCBI chr20:4,832,013...4,835,516
Ensembl chr20:4,830,053...4,833,620

G

RIO kinase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of RIOK1 mRNA

NCBI chr17:26,767,440...26,789,900
Ensembl chr17:26,766,947...26,789,900

G

ribosomal oxygenase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RIOX1 mRNA

NCBI chr 6:109,310,748...109,313,365
Ensembl chr 6:103,579,642...103,582,250

G

ribosomal oxygenase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of RIOX2 mRNA

NCBI chr11:54,327,311...54,353,989
Ensembl chr11:40,860,774...40,884,574

G

receptor-interacting serine-threonine kinase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of RIPK2 mRNA

NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657

G

RHO family interacting cell polarization regulator 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RIPOR2 mRNA

NCBI chr17:40,751,771...40,975,611
Ensembl chr17:40,323,867...40,548,092

G

ribonuclease A family member 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RNASE4 mRNA

NCBI chr15:26,786,287...26,803,634
Ensembl chr15:24,312,464...24,330,117

G

Rho family GTPase 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of RND3 mRNA

NCBI chr 3:55,981,142...55,998,494
Ensembl chr 3:35,571,143...35,589,327

G

ring finger protein 13

affects methylation

perfluoro-n-nonanoic acid affects the methylation of RNF13 gene

NCBI chr 2:141,927,887...142,061,801
Ensembl chr 2:141,927,909...142,061,801

G

ring finger protein 152

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RNF152 mRNA

NCBI chr13:21,838,634...21,918,000
Ensembl chr13:21,323,824...21,403,113

G

ring finger protein 187

increases expression

perfluoro-n-nonanoic acid results in increased expression of RNF187 mRNA

NCBI chr10:43,709,493...43,715,392
Ensembl chr10:43,702,357...43,716,157

G

ring finger protein 43

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RNF43 mRNA

NCBI chr10:72,958,744...73,034,540
Ensembl chr10:72,464,348...72,536,977

G

ribosome production factor 2 homolog

increases expression

perfluoro-n-nonanoic acid results in increased expression of RPF2 mRNA

NCBI chr20:45,184,511...45,205,983
Ensembl chr20:43,629,951...43,651,509

G

ribosomal protein L10 like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL10L mRNA

NCBI chr 6:90,280,962...90,281,982
Ensembl chr 6:84,543,540...84,545,816

G

ribosomal protein L13

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL13 mRNA

NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
Ensembl chr 3:51,153,924...51,163,014

G

ribosomal protein L22 like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of RPL22L1 mRNA

NCBI chr 2:111,754,687...111,756,623
Ensembl chr 2:111,754,687...111,756,625

G

ribosomal protein L23

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL23 mRNA

NCBI chr10:83,268,223...83,272,184
Ensembl chr10:82,771,538...82,775,870

G

ribosomal protein L24

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL24 mRNA

NCBI chr11:58,122,997...58,128,405
Ensembl chr11:44,653,937...44,659,370

G

ribosomal protein L27A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL27A mRNA

NCBI chr 1:163,539,732...163,542,771

G

ribosomal protein L28

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL28 mRNA

NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032

G

ribosomal protein L3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL3 mRNA

NCBI chr 7:111,622,255...111,627,640
Ensembl chr 7:111,621,610...111,636,468

G

ribosomal protein L36

increases expression

perfluoro-n-nonanoic acid results in increased expression of RPL36 mRNA

NCBI chr 9:1,529,117...1,534,534
Ensembl chr 6:98,809,534...98,809,897
Ensembl chr 5:98,809,534...98,809,897

G

ribosomal protein L37

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL37 mRNA

NCBI chr 2:54,215,469...54,217,429
Ensembl chr 2:54,215,469...54,217,442

G

ribosomal protein L37A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL37A mRNA

NCBI chr 9:74,298,843...74,300,926

G

ribosomal protein L38

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL38 mRNA

NCBI chr10:99,701,330...99,705,004
Ensembl chr10:99,701,362...99,705,004
Ensembl chr14:99,701,362...99,705,004
Ensembl chr 3:99,701,362...99,705,004
Ensembl chr 2:99,701,362...99,705,004
Ensembl chr16:99,701,362...99,705,004

G

ribosomal protein L39

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL39 mRNA

NCBI chr  X:116,327,216...116,330,211
Ensembl chr18:6,326,330...6,326,692
Ensembl chr  X:6,326,330...6,326,692
Ensembl chr  X:6,326,330...6,326,692
Ensembl chr15:6,326,330...6,326,692
Ensembl chr20:6,326,330...6,326,692
Ensembl chr 7:6,326,330...6,326,692

G

ribosomal protein L5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL5 mRNA

NCBI chr14:1,988,792...1,995,236
Ensembl chr14:1,843,770...1,850,290

G

ribosomal protein L7A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL7A mRNA

NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716
Ensembl chr18:10,239,001...10,241,716

G

ribosomal protein L8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPL8 mRNA

NCBI chr 7:110,506,815...110,509,106
Ensembl chr 7:108,622,324...108,628,482
Ensembl chr 3:108,622,324...108,628,482

G

ribosomal protein lateral stalk subunit P0

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPLP0 mRNA

NCBI chr12:46,715,121...46,718,390
Ensembl chr12:41,054,179...41,057,632

G

ribosomal protein lateral stalk subunit P2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPLP2 mRNA

NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645

G

ribonuclease P/MRP subunit p40

increases expression

perfluoro-n-nonanoic acid results in increased expression of RPP40 mRNA

NCBI chr17:28,947,752...28,956,788
Ensembl chr17:28,947,734...28,956,788

G

ribosomal protein S11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPS11 mRNA

NCBI chr 1:95,605,690...95,607,798
Ensembl chr 1:95,605,692...95,607,874

G

ribosomal protein S12

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPS12 mRNA

NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014

G

ribosomal protein S2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPS2 mRNA

NCBI chr10:14,251,841...14,253,697
Ensembl chr10:13,747,301...13,749,163

G

ribosomal protein S20

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of RPS20 mRNA

NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475
Ensembl chr 9:16,819,304...16,820,475
Ensembl chr 3:16,819,304...16,820,475
Ensembl chr 5:16,819,304...16,820,475

G

ribosomal protein S21, pseudogene 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPS21 mRNA

NCBI chr 5:158,670,141...158,670,484
Ensembl chr 5:153,387,176...153,387,427

G

ribosomal protein S23

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPS23 mRNA

NCBI chr 2:23,814,517...23,816,087
Ensembl chr 2:22,079,302...22,080,918

G

ribosomal protein S24

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPS24 mRNA

NCBI chr16:95,429...101,146
Ensembl chr16:89,604...94,279

G

ribosomal protein S29

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPS29 mRNA

NCBI chr 6:93,371,293...93,372,731
Ensembl chr 6:87,635,230...87,636,636
Ensembl chr13:87,635,230...87,636,636

G

ribosomal protein SA

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPSA mRNA

NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:119,851,225...119,855,247

G

RNA pseudouridine synthase D4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RPUSD4 mRNA

NCBI chr 8:33,617,384...33,626,873
Ensembl chr 8:33,617,379...33,626,873

G

Ras-related GTP binding C

increases expression

perfluoro-n-nonanoic acid results in increased expression of RRAGC mRNA

NCBI chr 5:136,148,239...136,167,773
Ensembl chr 5:136,148,276...136,167,767

G

ribonucleotide reductase catalytic subunit M1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RRM1 mRNA

NCBI chr 1:166,235,904...166,260,206
Ensembl chr 1:156,823,960...156,848,261

G

ribonucleotide reductase regulatory subunit M2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RRM2 mRNA

NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:41,340,557...41,346,773

G

RRN3 homolog, RNA polymerase I transcription factor

increases expression

perfluoro-n-nonanoic acid results in increased expression of RRN3 mRNA

NCBI chr10:2,637,016...2,672,338
Ensembl chr10:2,129,978...2,165,663

G

ribosomal RNA processing 12

increases expression

perfluoro-n-nonanoic acid results in increased expression of RRP12 mRNA

NCBI chr 1:240,672,378...240,705,992
Ensembl chr 1:240,672,382...240,706,018

G

ribosome biogenesis regulator 1 homolog

increases expression

perfluoro-n-nonanoic acid results in increased expression of RRS1 mRNA

NCBI chr 5:14,516,303...14,517,936
Ensembl chr 5:9,733,091...9,735,140

G

ribosomal L24 domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of RSL24D1 mRNA

NCBI chr 8:82,733,627...82,742,632
Ensembl chr 8:73,852,996...73,862,001

G

reticulon 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RTN1 mRNA

NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436

G

RUN and FYVE domain containing 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of RUFY3 mRNA

NCBI chr14:19,715,593...19,790,530
Ensembl chr14:19,432,524...19,507,004

G

RUNX family transcription factor 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of RUNX2 mRNA

NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167

G

S100 calcium binding protein A14

increases expression

perfluoro-n-nonanoic acid results in increased expression of S100A14 mRNA

NCBI chr 2:178,305,976...178,308,004
Ensembl chr 2:176,008,395...176,010,423

G

S100 calcium-binding protein A4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of S100A4 mRNA

NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:176,091,804...176,093,254

G

S100 calcium binding protein A8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of S100A8 mRNA

PMID:32588087 PMID:38568856

NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:176,167,124...176,167,643

G

S100 calcium binding protein A9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of S100A9 mRNA

NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:176,190,361...176,193,230

G

S100 calcium binding protein G

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of S100G mRNA

NCBI chr X:35,337,636...35,340,205
Ensembl chr X:31,705,866...31,708,433

G

sphingosine-1-phosphate receptor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of S1PR1 mRNA

NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:203,621,587...203,629,681

G

sterile alpha motif domain containing 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SAMD11 mRNA

NCBI chr 5:172,113,900...172,142,026
Ensembl chr 5:166,831,663...166,850,009

G

sarcosine dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SARDH mRNA

NCBI chr 3:30,908,621...30,973,409
Ensembl chr 3:10,510,553...10,573,874

G

spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SART1 mRNA

NCBI chr 1:212,119,824...212,128,517
Ensembl chr 1:202,690,459...202,699,136

G

SET binding factor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SBF1 mRNA

NCBI chr 7:122,237,968...122,264,591
Ensembl chr 7:120,358,338...120,384,902

G

strawberry notch homolog 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SBNO2 mRNA

NCBI chr 7:10,256,221...10,300,175
Ensembl chr 7:9,605,627...9,649,527

G

sterol-C5-desaturase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SC5D mRNA

NCBI chr 8:51,526,669...51,538,277
Ensembl chr 8:42,632,672...42,641,273

G

SR-related CTD-associated factor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SCAF1 mRNA

NCBI chr 1:95,485,448...95,499,389
Ensembl chr 1:95,485,448...95,496,029

G

scavenger receptor class A, member 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SCARA3 mRNA

NCBI chr15:44,315,422...44,348,416
Ensembl chr15:40,140,161...40,172,894

G

scavenger receptor class B, member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SCARB1 mRNA

NCBI chr12:36,957,302...37,023,982
Ensembl chr12:31,296,156...31,362,647

G

stearoyl-CoA desaturase

affects expression
multiple interactions
increases expression

perfluoro-n-nonanoic acid affects the expression of SCD1 mRNA
PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of SCD1 mRNA]
perfluoro-n-nonanoic acid results in increased expression of SCD mRNA

PMID:23567314 PMID:28049043

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562

G

secretogranin V

increases expression

perfluoro-n-nonanoic acid results in increased expression of SCG5 mRNA

NCBI chr 3:120,998,420...121,042,881
Ensembl chr 3:100,544,099...100,588,463

G

Scm polycomb group protein homolog 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SCMH1 mRNA

NCBI chr 5:133,991,167...134,115,893
Ensembl chr 5:133,990,520...134,122,105

G

sodium voltage-gated channel alpha subunit 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SCN1A mRNA

NCBI chr 3:71,360,840...71,479,870
Ensembl chr 3:50,952,791...51,071,699

G

sterol carrier protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SCP2 mRNA

NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:122,776,549...122,881,287

G

secernin 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SCRN2 mRNA

NCBI chr10:82,016,604...82,020,676
Ensembl chr10:82,016,649...82,020,675

G

stromal cell-derived factor 2-like 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SDF2L1 mRNA

NCBI chr11:97,376,878...97,379,120
Ensembl chr11:83,872,659...83,874,902

G

short chain dehydrogenase/reductase family 9C, member 7

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of SDR9C7 mRNA

NCBI chr 7:65,588,726...65,607,534
Ensembl chr 7:63,707,071...63,721,480

G

serine dehydratase-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of SDSL mRNA

NCBI chr12:41,760,252...41,770,465
Ensembl chr12:36,099,693...36,109,906

G

SEC14-like lipid binding 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SEC14L2 mRNA

NCBI chr14:83,197,384...83,222,059
Ensembl chr14:78,973,808...78,993,788

G

selenium binding protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SELENBP1 mRNA

NCBI chr 2:185,183,022...185,193,612
Ensembl chr 2:182,493,978...182,504,594

G

selenoprotein O

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SELENOO mRNA

NCBI chr 7:120,167,913...120,178,806
Ensembl chr 7:120,167,913...120,178,805

G

semaphorin 3D

increases expression

perfluoro-n-nonanoic acid results in increased expression of SEMA3D mRNA

NCBI chr 4:23,271,815...23,460,971
Ensembl chr 4:22,316,779...22,505,930

G

semaphorin 4B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SEMA4B mRNA

NCBI chr 1:143,545,727...143,587,037
Ensembl chr 1:134,149,536...134,177,775

G

semaphorin 4G

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SEMA4G mRNA

NCBI chr 1:253,799,552...253,814,504
Ensembl chr 1:243,853,854...243,865,341

G

SUMO specific peptidase 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SENP3 mRNA

NCBI chr10:54,889,445...54,898,359
Ensembl chr10:54,390,694...54,399,593

G

septin 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SEPTIN9 mRNA

NCBI chr10:102,908,557...103,077,789
Ensembl chr10:102,409,711...102,579,055

G

serine active site containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SERAC1 mRNA

NCBI chr 1:46,620,741...46,656,801
Ensembl chr 1:46,620,498...46,656,727

G

serpin family A member 10

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SERPINA10 mRNA

NCBI chr 6:128,520,894...128,529,332
Ensembl chr 6:122,756,108...122,764,544

G

serpin family A member 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SERPINA11 mRNA

NCBI chr 6:128,668,030...128,677,476
Ensembl chr 6:122,903,250...122,912,670

G

serpin family A member 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SERPINA7 mRNA

NCBI chr X:107,452,044...107,510,958
Ensembl chr X:102,663,405...102,669,040

G

serpin family D member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SERPIND1 mRNA

NCBI chr11:97,168,753...97,179,830
Ensembl chr11:83,664,518...83,675,519

G

serpin family E member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SERPINE1 mRNA

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657

G

serpin family E member 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SERPINE2 mRNA

NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:81,124,804...81,188,826

G

serpin family F member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SERPINF1 mRNA

NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,249,708...60,262,646

G

sestrin 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SESN2 mRNA

NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:144,701,530...144,721,260

G

sestrin 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SESN3 mRNA

NCBI chr 8:19,415,307...19,470,943
Ensembl chr 8:11,133,678...11,185,842

G

SET binding protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SETBP1 mRNA

NCBI chr18:74,465,616...74,827,455
Ensembl chr18:72,191,035...72,552,556

G

splicing factor 3A subunit 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SF3A2 mRNA

NCBI chr 7:9,560,182...9,566,205
Ensembl chr 7:8,909,507...8,915,530

G

SFI1 centrin binding protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SFI1 mRNA

NCBI chr14:77,990,965...78,048,352
Ensembl chr14:77,990,965...78,048,255

G

Scm-like with four mbt domains 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SFMBT2 mRNA

NCBI chr17:72,844,037...73,038,599
Ensembl chr17:67,935,904...68,128,781

G

stratifin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SFN mRNA

NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:145,826,201...145,831,314

G

SFT2 domain containing 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SFT2D2 mRNA

NCBI chr13:80,017,854...80,037,144
Ensembl chr13:77,484,636...77,504,112

G

sideroflexin 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SFXN3 mRNA

NCBI chr 1:243,907,958...243,917,065
Ensembl chr 1:243,907,751...243,917,073

G

sideroflexin 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of SFXN4 mRNA

NCBI chr 1:259,976,480...259,998,778
Ensembl chr 1:259,976,481...259,998,754

G

sideroflexin 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SFXN5 mRNA

NCBI chr 4:119,307,692...119,427,531
Ensembl chr 4:117,752,806...117,869,794

G

sphingosine-1-phosphate lyase 1

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of SGPL1 mRNA
perfluoro-n-nonanoic acid results in increased expression of SGPL1 mRNA

PMID:25812627 PMID:32588087

NCBI chr20:29,590,652...29,637,064
Ensembl chr20:29,047,796...29,094,084

G

small glutamine rich tetratricopeptide repeat co-chaperone beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of SGTB mRNA

NCBI chr 2:36,966,840...37,003,318
Ensembl chr 2:35,233,042...35,269,518

G

SH2B adaptor protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of SH2B3 mRNA

NCBI chr12:40,391,755...40,414,336
Ensembl chr12:34,731,911...34,753,616

G

SH3 domain binding glutamate-rich protein like 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SH3BGRL2 mRNA

NCBI chr 8:93,341,104...93,433,143
Ensembl chr 8:84,461,121...84,551,564

G

SH3-domain binding protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SH3BP2 mRNA

NCBI chr14:76,176,097...76,213,300
Ensembl chr14:76,176,101...76,213,251

G

SH3-domain binding protein 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of SH3BP5 mRNA

NCBI chr16:6,589,877...6,676,524
Ensembl chr16:6,583,465...6,698,975

G

SH3 domain containing ring finger 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SH3RF2 mRNA

NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856

G

sex hormone binding globulin

increases expression

perfluoro-n-nonanoic acid results in increased expression of SHBG mRNA

NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,332,941...54,351,057

G

serine hydroxymethyltransferase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SHMT2 mRNA

NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:63,358,961...63,364,236

G

SHQ1, H/ACA ribonucleoprotein assembly factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SHQ1 mRNA

NCBI chr 4:134,741,190...134,861,960
Ensembl chr 4:133,213,361...133,305,586

G

siah E3 ubiquitin protein ligase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SIAH2 mRNA

NCBI chr 2:145,063,847...145,081,675
Ensembl chr 2:142,914,003...142,931,950

G

siah E3 ubiquitin protein ligase family member 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of SIAH3 mRNA

NCBI chr15:50,770,839...50,838,213
Ensembl chr15:50,770,871...50,834,487

G

SID1 transmembrane family, member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SIDT2 mRNA

NCBI chr 8:55,129,091...55,146,446
Ensembl chr 8:46,232,383...46,248,700

G

salt-inducible kinase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SIK1 mRNA

NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,396...9,958,991

G

S-phase kinase associated protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SKP2 mRNA

NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:58,161,229...58,189,338

G

solute carrier family 10 member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC10A1 mRNA

NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:100,613,045...100,626,670

G

solute carrier family 10 member 2

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of SLC10A2 mRNA

NCBI chr16:91,088,089...91,111,025
Ensembl chr16:84,374,862...84,409,475

G

solute carrier family 10, member 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC10A5 mRNA

NCBI chr 2:93,364,959...93,366,263
Ensembl chr 2:91,444,454...91,489,651

G

solute carrier family 12, member 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC12A9 mRNA

NCBI chr12:25,005,741...25,022,628
Ensembl chr12:19,369,004...19,385,877

G

solute carrier family 15 member 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC15A4 mRNA

NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480

G

solute carrier family 16 member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC16A1 mRNA

NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:192,124,289...192,144,611

G

solute carrier family 16 member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC16A2 mRNA

NCBI chr X:72,791,096...72,914,299
Ensembl chr X:68,723,261...68,848,771

G

solute carrier family 16, member 9

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC16A9 mRNA

NCBI chr20:18,335,862...18,377,125
Ensembl chr20:18,335,862...18,377,022

G

solute carrier family 17 member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC17A1 mRNA

NCBI chr17:41,647,332...41,683,078
Ensembl chr17:41,222,049...41,253,304

G

solute carrier family 17 member 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC17A3 mRNA

NCBI chr17:41,270,804...41,300,132
Ensembl chr17:41,270,812...41,295,256

G

solute carrier family 17 member 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC17A5 mRNA

NCBI chr 8:88,274,497...88,309,734

G

solute carrier family 1 member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC1A1 mRNA

NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:226,549,842...226,630,402

G

solute carrier family 1 member 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC1A4 mRNA

NCBI chr14:98,718,646...98,761,672
Ensembl chr14:94,529,084...94,560,418

G

solute carrier family 1 member 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC1A5 mRNA

NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:77,456,694...77,470,952

G

solute carrier family 22 member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC22A1 mRNA

NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:48,076,666...48,103,678

G

solute carrier family 22 member 12

multiple interactions

[Chlorine co-treated with perfluoro-n-nonanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]

NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555

G

solute carrier family 22, member 15

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC22A15 mRNA

NCBI chr 2:191,987,409...192,049,859
Ensembl chr 2:189,298,832...189,358,792

G

solute carrier family 22 member 22

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC22A10 mRNA

NCBI chr 7:90,610,007...90,639,718
Ensembl chr 7:88,720,427...88,750,111

G

solute carrier family 22 member 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC22A5 mRNA

NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,008,311...38,035,309

G

solute carrier family 22 member 6

multiple interactions

[perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of SLC22A6 protein

NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:205,522,729...205,531,173

G

solute carrier family 22 member 7

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of SLC22A7 mRNA

NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:14,547,849...14,553,921

G

solute carrier family 22 member 8

increases uptake

SLC22A8 protein results in increased uptake of perfluoro-n-nonanoic acid

NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:205,498,084...205,517,450

G

solute carrier family 23 member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC23A1 mRNA

NCBI chr18:27,490,549...27,504,563
Ensembl chr18:27,216,281...27,230,697

G

solute carrier family 25 member 13

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC25A13 mRNA

NCBI chr 4:35,145,721...35,328,403
Ensembl chr 4:34,179,224...34,361,902

G

solute carrier family 25 member 18

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC25A18 mRNA

NCBI chr 4:154,000,808...154,021,373
Ensembl chr 4:154,000,990...154,021,372

G

solute carrier family 25 member 20

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC25A20 mRNA

NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:109,365,002...109,386,512

G

solute carrier family 25 member 29

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC25A29 mRNA

NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940

G

solute carrier family 25 member 33

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC25A33 mRNA

NCBI chr 5:160,195,040...160,219,961
Ensembl chr 5:160,195,042...160,219,961

G

solute carrier family 25, member 44

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC25A44 mRNA

NCBI chr 2:173,868,317...173,883,137
Ensembl chr 2:173,868,320...173,883,020

G

solute carrier family 25 member 5, pseudogene 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC25A6 mRNA

NCBI chr18:70,846,358...70,847,597
Ensembl chr18:68,571,300...68,572,199

G

solute carrier family 26 member 7

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC26A7 mRNA

NCBI chr 5:32,681,653...32,819,110
Ensembl chr 5:27,887,042...28,021,658

G

solute carrier family 27 member 1

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of SLC27A1 mRNA

NCBI chr16:18,311,859...18,337,024
Ensembl chr16:18,278,984...18,296,063

G

solute carrier family 27 member 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC27A2 mRNA

NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:113,804,728...113,842,208

G

solute carrier family 28 member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC28A1 mRNA

NCBI chr 1:144,490,453...144,532,025
Ensembl chr 1:135,081,385...135,122,464

G

solute carrier family 2 member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC2A1 mRNA

NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 2 member 12

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC2A12 mRNA

NCBI chr 1:24,623,558...24,683,577
Ensembl chr 1:22,804,418...22,860,971

G

solute carrier family 2 member 2

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of SLC2A2 mRNA
perfluoro-n-nonanoic acid results in decreased expression of SLC2A2 mRNA

PMID:22387981 PMID:32588087

NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:111,611,774...111,639,933

G

solute carrier family 31 member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC31A2 mRNA

NCBI chr 5:80,753,589...80,764,126
Ensembl chr 5:75,738,024...75,748,542

G

solute carrier family 35 member D1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC35D1 mRNA

NCBI chr 5:123,157,739...123,210,350
Ensembl chr 5:117,934,352...117,981,311

G

solute carrier family 35, member F2

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of SLC35F2 mRNA

NCBI chr 8:63,055,503...63,099,791
Ensembl chr 8:54,159,970...54,203,612

G

solute carrier family 35, member F3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC35F3 mRNA

NCBI chr19:54,102,811...54,371,765
Ensembl chr19:54,103,120...54,372,839

G

solute carrier family 35, member F6

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC35F6 mRNA

NCBI chr 6:31,445,738...31,457,580
Ensembl chr 6:25,725,819...25,737,730

G

solute carrier family 37 member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC37A1 mRNA

NCBI chr20:9,361,733...9,435,227
Ensembl chr20:9,378,836...9,433,892

G

solute carrier family 37 member 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC37A2 mRNA

NCBI chr 8:45,134,596...45,160,551
Ensembl chr 8:36,946,930...36,971,482

G

solute carrier family 37 member 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC37A4 mRNA

NCBI chr 8:53,619,952...53,626,110
Ensembl chr 8:44,723,339...44,729,301

G

solute carrier family 38, member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC38A1 mRNA

NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:127,738,226...127,802,218

G

solute carrier family 38, member 10

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC38A10 mRNA

NCBI chr10:105,386,836...105,436,636
Ensembl chr10:105,386,836...105,436,636

G

solute carrier family 38, member 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC38A3 mRNA

NCBI chr 8:117,202,534...117,220,310
Ensembl chr 8:108,323,894...108,339,988

G

solute carrier family 3 member 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC3A2 mRNA

NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:205,604,468...205,618,931

G

solute carrier family 40 member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC40A1 mRNA

NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:48,033,526...48,051,481

G

solute carrier family 43 member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC43A1 mRNA

NCBI chr 3:90,327,250...90,353,438
Ensembl chr 3:69,920,649...69,946,768

G

solute carrier family 43, member 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC43A3 mRNA

NCBI chr 3:70,008,160...70,030,324
Ensembl chr 3:70,009,313...70,029,749

G

solute carrier family 46, member 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC46A3 mRNA

NCBI chr12:12,176,776...12,193,256
Ensembl chr12:7,140,668...7,157,092

G

solute carrier family 47 member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC47A1 mRNA

NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,034,122...46,087,637

G

solute carrier family 50 member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC50A1 mRNA

NCBI chr 2:174,677,985...174,680,366
Ensembl chr 2:174,677,708...174,680,366

G

solute carrier family 5 member 12

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC5A12 mRNA

NCBI chr 3:117,633,885...117,683,966
Ensembl chr 3:97,179,326...97,228,405

G

solute carrier family 5 member 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC5A9 mRNA

NCBI chr 5:131,937,368...131,966,405
Ensembl chr 5:126,709,769...126,733,468

G

solute carrier family 6 member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC6A1 mRNA

NCBI chr 4:149,004,447...149,037,840
Ensembl chr 4:147,466,965...147,482,293

G

solute carrier family 6 member 2

affects methylation

perfluoro-n-nonanoic acid affects the methylation of SLC6A2 gene

NCBI chr19:30,183,289...30,228,292
Ensembl chr19:14,010,386...14,050,357

G

solute carrier family 6 member 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC6A8 mRNA

NCBI chr X:156,536,017...156,545,321
Ensembl chr X:151,384,675...151,393,979

G

solute carrier family 6 member 9

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC6A9 mRNA

NCBI chr 5:136,660,022...136,694,173
Ensembl chr 5:131,374,542...131,408,728

G

solute carrier family 7 member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC7A1 mRNA

NCBI chr12:11,664,488...11,740,030
Ensembl chr12:6,628,007...6,703,849

G

solute carrier family 7 member 11

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC7A11 mRNA

NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:133,963,107...134,517,536

G

solute carrier family 7 member 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC7A2 mRNA

NCBI chr16:58,115,991...58,174,256
Ensembl chr16:51,417,493...51,470,784

G

solute carrier family 7 member 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLC7A5 mRNA

NCBI chr19:66,843,808...66,872,412
Ensembl chr19:49,935,220...49,963,823

G

solute carrier family 9 member A1

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of SLC9A1 mRNA
perfluoro-n-nonanoic acid results in decreased expression of SLC9A1 mRNA

PMID:32588087 PMID:38568856

NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:145,576,334...145,629,624

G

solute carrier organic anion transporter family, member 1a4

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of SLCO1A4 mRNA

NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:174,710,004...175,254,573

G

solute carrier organic anion transporter family member 1B2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLCO1B2 mRNA

NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:174,551,480...174,619,981

G

solute carrier organic anion transporter family, member 2a1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLCO2A1 mRNA

NCBI chr 8:103,588,916...103,672,546
Ensembl chr 8:103,588,916...103,672,546

G

solute carrier organic anion transporter family, member 2b1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLCO2B1 mRNA

NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:153,959,293...154,007,353

G

solute carrier organic anion transporter family, member 4C1

decreases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of SLCO4C1 mRNA
perfluoro-n-nonanoic acid results in decreased expression of SLCO4C1 protein
[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] inhibits the reaction [perfluoro-n-nonanoic acid results in decreased expression of SLCO4C1 protein]

PMID:25588985 PMID:32588087

NCBI chr 9:104,624,802...104,676,462
Ensembl chr 9:97,178,861...97,229,715

G

schlafen family member 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of SLFN5 mRNA

NCBI chr10:67,881,068...67,895,013
Ensembl chr10:67,880,009...67,893,109

G

SMAD family member 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SMAD3 mRNA

NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960

G

structural maintenance of chromosomes 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SMC4 mRNA

NCBI chr 2:155,550,262...155,578,695
Ensembl chr 2:153,240,283...153,271,571

G

small leucine-rich protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SMLR1 mRNA

NCBI chr 1:19,837,390...19,858,906

G

spermine oxidase

increases expression

perfluoro-n-nonanoic acid results in increased expression of SMOX mRNA

NCBI chr 3:139,184,793...139,220,174
Ensembl chr 3:118,731,900...118,765,710
Ensembl chr X:118,731,900...118,765,710

G

sphingomyelin phosphodiesterase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SMPD2 mRNA

NCBI chr20:46,568,627...46,571,741
Ensembl chr20:44,986,231...44,989,441

G

snail family transcriptional repressor 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SNAI2 mRNA

NCBI chr11:99,686,934...99,690,349
Ensembl chr11:86,181,909...86,186,200

G

syntaphilin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SNPH mRNA

NCBI chr 3:160,558,929...160,603,636
Ensembl chr 3:140,099,708...140,139,453

G

small nuclear ribonucleoprotein U11/U12 subunit 35

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SNRNP35 mRNA

NCBI chr12:32,112,032...32,119,829
Ensembl chr12:32,110,993...32,122,660

G

small nuclear ribonucleoprotein U1 subunit 70

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SNRNP70 mRNA

NCBI chr 1:104,992,518...105,012,851
Ensembl chr 1:95,856,036...95,876,392

G

syntrophin, beta 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SNTB1 mRNA

NCBI chr 7:88,950,642...89,219,017
Ensembl chr 7:87,060,926...87,329,315

G

sentan, cilia apical structure protein

increases expression

perfluoro-n-nonanoic acid results in increased expression of SNTN mRNA

NCBI chr15:11,512,563...11,525,608
Ensembl chr15:11,512,563...11,525,603

G

sine oculis binding protein homolog

increases expression

perfluoro-n-nonanoic acid results in increased expression of SOBP mRNA

NCBI chr20:48,064,445...48,243,607
Ensembl chr20:46,482,765...46,663,541

G

superoxide dismutase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SOD2 mRNA

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189

G

sorbitol dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SORD mRNA

NCBI chr 3:129,638,282...129,669,727
Ensembl chr 3:109,184,676...109,216,133

G

SRY-box transcription factor 13

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SOX13 mRNA

NCBI chr13:47,383,145...47,427,572
Ensembl chr13:44,831,085...44,875,762

G

SRY-box transcription factor 9

increases expression

perfluoro-n-nonanoic acid results in increased expression of SOX9 mRNA

NCBI chr10:98,305,744...98,311,250
Ensembl chr10:97,806,485...97,811,994

G

sperm associated antigen 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SPAG5 mRNA

NCBI chr10:63,693,300...63,714,813
Ensembl chr10:63,198,768...63,216,745

G

secreted protein acidic and cysteine rich

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SPARC mRNA

NCBI chr10:40,017,065...40,038,816
Ensembl chr10:39,516,406...39,538,396

G

SPARC like 1

affects expression

perfluoro-n-nonanoic acid affects the expression of SPARCL1 protein

NCBI chr14:5,937,484...5,968,532
Ensembl chr14:5,632,569...5,663,865

G

SPC24 component of NDC80 kinetochore complex

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SPC24 mRNA

NCBI chr 8:28,576,409...28,581,481
Ensembl chr 8:20,300,319...20,305,310

G

spire-type actin nucleation factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SPIRE1 mRNA

NCBI chr18:63,311,800...63,441,545
Ensembl chr18:61,041,290...61,171,899

G

spondin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SPON1 protein

NCBI chr 1:177,363,526...177,662,689
Ensembl chr 1:167,928,972...168,228,226

G

secreted phosphoprotein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SPP2 mRNA

NCBI chr 9:89,006,858...89,026,676
Ensembl chr 9:89,007,175...89,026,688

G

spectrin, beta, non-erythrocytic 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SPTBN2 mRNA

NCBI chr 1:211,432,373...211,473,016
Ensembl chr 1:202,002,970...202,044,283

G

serine palmitoyltransferase, long chain base subunit 3

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of SPTLC3 mRNA

NCBI chr 3:147,301,570...147,431,696
Ensembl chr 3:126,847,878...126,978,010

G

spexin hormone

increases expression

perfluoro-n-nonanoic acid results in increased expression of SPX mRNA

PMID:25812627 PMID:32588087

NCBI chr 4:177,087,053...177,093,091
Ensembl chr 4:175,356,247...175,362,082

G

squalene epoxidase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SQLE mRNA

NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:90,868,011...90,883,618

G

steroid 5 alpha-reductase 1

decreases activity

perfluoro-n-nonanoic acid results in decreased activity of SRD5A1 protein

NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461

G

sterol regulatory element binding transcription factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SREBF1 mRNA

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650

G

sulfiredoxin 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of SRXN1 mRNA

PMID:28558994 PMID:32588087

NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:140,599,608...140,628,448

G

scavenger receptor cysteine rich family member with 5 domains

affects expression

perfluoro-n-nonanoic acid affects the expression of SSC5D protein

NCBI chr 1:68,891,942...68,910,462
Ensembl chr 1:68,891,949...68,909,743

G

signal sequence receptor subunit 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SSR2 mRNA

NCBI chr 2:174,048,291...174,057,043
Ensembl chr 2:174,048,460...174,057,042

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of ST3GAL5 mRNA

NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558

G

ST6 beta-galactoside alpha-2,6-sialyltransferase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ST6GAL1 mRNA

NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310

G

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ST6GALNAC2 mRNA

NCBI chr10:102,409,048...102,427,299
Ensembl chr10:101,909,971...101,915,008
Ensembl chr10:101,909,971...101,915,008

G

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ST6GALNAC6 mRNA

NCBI chr 3:15,894,275...15,907,502
Ensembl chr 3:15,885,968...15,907,496

G

stabilin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of STAB1 mRNA

NCBI chr16:6,336,871...6,367,374
Ensembl chr16:6,330,444...6,360,923

G

SH3 and cysteine rich domain

increases expression

perfluoro-n-nonanoic acid results in increased expression of STAC mRNA

NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:111,530,800...111,654,008

G

steroidogenic acute regulatory protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of STAR mRNA; perfluoro-n-nonanoic acid results in decreased expression of STAR protein

NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672

G

StAR-related lipid transfer domain containing 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of STARD4 mRNA

NCBI chr18:25,088,831...25,104,172
Ensembl chr18:24,817,107...24,830,024

G

StAR-related lipid transfer domain containing 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of STARD5 mRNA

NCBI chr 1:147,015,304...147,025,170
Ensembl chr 1:137,606,177...137,616,469

G

signal transducer and activator of transcription 5B

decreases activity

perfluoro-n-nonanoic acid results in decreased activity of STAT5B protein

NCBI chr10:86,205,148...86,276,178
Ensembl chr10:85,705,670...85,775,668

G

stanniocalcin 1

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of STC1 mRNA
perfluoro-n-nonanoic acid results in increased expression of STC1 mRNA

PMID:32588087 PMID:38568856

NCBI chr15:50,709,439...50,720,093
Ensembl chr15:44,299,621...44,310,264

G

stanniocalcin 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of STC2 mRNA

NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,250,853...16,262,973

G

serine/threonine kinase 32A

increases expression

perfluoro-n-nonanoic acid results in increased expression of STK32A mRNA

NCBI chr18:35,258,865...35,374,985
Ensembl chr18:35,259,052...35,369,451

G

stum, mechanosensory transduction mediator homolog

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of STUM mRNA

NCBI chr13:92,172,175...92,227,205
Ensembl chr13:92,173,544...92,227,213

G

sulfotransferase family 1C member 2A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SULT1C2 mRNA

NCBI chr 9:7,075,873...7,103,316
Ensembl chr 9:6,874,249...6,904,734

G

sulfotransferase family 2A member 1

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of SULT2A1 mRNA
perfluoro-n-nonanoic acid results in increased expression of SULT2A1 mRNA

PMID:32588087 PMID:35337807

NCBI chr 1:84,582,011...84,639,001
Ensembl chr 1:74,911,100...75,508,134

G

Sad1 and UNC84 domain containing 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SUN2 mRNA

PMID:25812627 PMID:38568856

NCBI chr 7:111,275,374...111,292,565
Ensembl chr 7:111,275,380...111,292,553

G

sulfite oxidase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SUOX mRNA

PMID:25812627 PMID:32588087

NCBI chr 7:1,687,666...1,691,759
Ensembl chr 7:1,103,151...1,107,038

G

SPT16 homolog, facilitates chromatin remodeling subunit

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SUPT16H mRNA

NCBI chr15:27,341,196...27,378,314
Ensembl chr15:24,866,489...24,904,846

G

Suv3 like RNA helicase

increases expression

perfluoro-n-nonanoic acid results in increased expression of SUPV3L1 mRNA

NCBI chr20:30,921,248...30,941,779
Ensembl chr20:30,378,550...30,399,054

G

surfeit 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SURF2 mRNA

NCBI chr 3:30,642,735...30,648,525
Ensembl chr 3:10,244,654...10,250,077

G

surfeit 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SURF6 mRNA

NCBI chr 3:10,221,450...10,232,306
Ensembl chr 3:10,221,452...10,232,251

G

sushi domain containing 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of SUSD2 mRNA

NCBI chr20:13,016,960...13,024,264
Ensembl chr20:13,017,477...13,024,903

G

sushi domain containing 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SUSD4 mRNA

NCBI chr13:96,982,867...97,109,419
Ensembl chr13:94,455,165...94,577,750

G

SUV39H1 histone lysine methyltransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SUV39H1 mRNA

NCBI chr X:17,093,059...17,105,942
Ensembl chr X:14,421,109...14,433,982

G

SUV39H1 histone lysine methyltransferase, pseudogene 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SUV39H1 mRNA

NCBI chr X:146,828,818...146,831,485

G

synaptotagmin 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SYT7 mRNA

NCBI chr 1:216,456,148...216,518,718
Ensembl chr 1:207,031,592...207,089,026

G

synaptotagmin-like 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SYTL2 mRNA

NCBI chr 1:153,685,403...153,791,758
Ensembl chr 1:144,273,360...144,379,222

G

TATA-box binding protein associated factor 15

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TAF15 mRNA

NCBI chr10:68,770,408...68,802,458
Ensembl chr10:68,272,969...68,304,949

G

transporter 1, ATP binding cassette subfamily B member

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TAP1 mRNA

NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,656,263...4,666,901

G

threonyl-tRNA synthetase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of TARS1 mRNA

NCBI chr 2:62,095,978...62,114,802
Ensembl chr 2:60,367,796...60,387,717

G

TatD DNase domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of TATDN1 mRNA

NCBI chr 7:92,339,452...92,370,445
Ensembl chr 7:90,441,079...90,481,133

G

TBC1 domain family, member 10C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TBC1D10C mRNA

NCBI chr 1:210,906,621...210,913,649
Ensembl chr 1:201,477,157...201,564,920

G

transducin (beta)-like 1 X-linked

increases expression

perfluoro-n-nonanoic acid results in increased expression of TBL1X mRNA

NCBI chr X:45,452,983...45,609,532
Ensembl chr X:41,576,047...41,731,101

G

transforming growth factor beta regulator 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of TBRG1 mRNA

NCBI chr 8:37,355,274...37,362,933
Ensembl chr 8:37,354,658...37,362,930

G

transcription elongation factor A1

increases expression

perfluoro-n-nonanoic acid results in increased expression of TCEA1 mRNA

NCBI chr 5:19,414,351...19,466,629
Ensembl chr 5:14,631,454...14,668,745
Ensembl chr15:14,631,454...14,668,745

G

transcription elongation factor A3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TCEA3 mRNA

NCBI chr 5:148,476,941...148,509,452
Ensembl chr 5:148,476,941...148,509,448

G

trichoplein, keratin filament binding

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TCHP mRNA

NCBI chr12:47,538,520...47,553,895
Ensembl chr12:41,877,889...41,892,427

G

tyrosyl-DNA phosphodiesterase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TDP1 mRNA

NCBI chr 6:124,892,821...124,960,646
Ensembl chr 6:119,163,166...119,231,021

G

trans-2,3-enoyl-CoA reductase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TECR mRNA

NCBI chr19:41,431,422...41,472,880
Ensembl chr19:24,541,615...24,568,168

G

telomere maintenance 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TELO2 mRNA

NCBI chr10:14,624,998...14,640,235
Ensembl chr10:14,120,818...14,135,698

G

testin LIM domain protein

increases expression

perfluoro-n-nonanoic acid results in increased expression of TES mRNA

NCBI chr 4:46,331,257...46,369,782
Ensembl chr 4:45,365,285...45,403,829

G

testis expressed 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TEX11 mRNA

NCBI chr X:69,973,012...70,236,544
Ensembl chr X:65,932,988...66,196,187

G

transferrin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TF mRNA; perfluoro-n-nonanoic acid results in decreased expression of TF protein

NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:103,767,995...103,816,511

G

tissue factor pathway inhibitor 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TFPI2 mRNA

NCBI chr 4:32,936,462...32,941,385
Ensembl chr 4:31,982,178...31,986,600

G

TGFB-induced factor homeobox 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TGIF2 mRNA

NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596
Ensembl chr17:145,333,418...145,348,596

G

tyrosine hydroxylase

multiple interactions

[perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in decreased expression of TH mRNA

NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767

G

thrombospondin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of THBS1 mRNA

NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:105,056,292...105,071,440

G

thimet oligopeptidase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of THOP1 mRNA

NCBI chr 7:9,283,617...9,295,957
Ensembl chr 7:8,632,916...8,645,275

G

thyroid hormone receptor alpha

affects binding
decreases expression

perfluoro-n-nonanoic acid binds to THRA protein
perfluoro-n-nonanoic acid results in decreased expression of THRA mRNA

PMID:24819616 PMID:38568856

NCBI chr10:84,198,141...84,225,659
Ensembl chr10:83,700,755...83,729,936

G

thyroid hormone responsive

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of THRSP mRNA

NCBI chr 1:161,134,640...161,138,964
Ensembl chr 1:151,723,086...151,728,075

G

TOPBP1-interacting checkpoint and replication regulator

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TICRR mRNA

NCBI chr 1:143,006,989...143,048,836
Ensembl chr 1:133,597,716...133,639,523

G

timeless circadian regulator

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TIMELESS mRNA

NCBI chr 7:1,239,388...1,263,344
Ensembl chr 7:654,822...678,738

G

translocase of inner mitochondrial membrane 44

increases expression

perfluoro-n-nonanoic acid results in increased expression of TIMM44 mRNA

NCBI chr12:7,410,424...7,428,179
Ensembl chr12:2,612,581...2,629,351

G

translocase of inner mitochondrial membrane 9

increases expression

perfluoro-n-nonanoic acid results in increased expression of TIMM9 mRNA

NCBI chr 6:95,346,065...95,358,895
Ensembl chr 6:89,610,094...89,622,924

G

tight junction protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TJP2 mRNA

NCBI chr 1:231,136,218...231,264,750
Ensembl chr 1:221,709,745...221,838,295

G

TLC domain containing 4

affects methylation

perfluoro-n-nonanoic acid affects the methylation of TLCD4 gene

NCBI chr 2:209,284,873...209,360,156
Ensembl chr 2:209,289,732...209,341,353

G

toll-like receptor 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of TLR3 mRNA

NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545

G

toll-like receptor 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TLR4 mRNA

NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628

G

transmembrane 4 L six family member 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TM4SF4 mRNA

NCBI chr 2:141,570,321...141,621,263
Ensembl chr 2:141,481,902...141,621,200

G

transmembrane 7 superfamily member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TM7SF2 mRNA

NCBI chr 1:212,785,217...212,789,572
Ensembl chr 1:203,355,931...203,360,270

G

transmembrane protein 106C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TMEM106C mRNA

NCBI chr 7:129,088,468...129,094,128
Ensembl chr 7:129,088,498...129,094,130

G

transmembrane protein 132A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TMEM132A mRNA

NCBI chr 1:207,507,074...207,518,756
Ensembl chr 1:207,507,077...207,518,758

G

transmembrane protein 138

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TMEM138 mRNA

NCBI chr 1:207,219,113...207,226,159

G

transmembrane protein 14A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TMEM14A mRNA

NCBI chr 9:31,137,011...31,148,794
Ensembl chr 9:23,733,039...23,734,463
Ensembl chr 9:23,733,039...23,734,463

G

transmembrane protein 14C

increases expression

perfluoro-n-nonanoic acid results in increased expression of TMEM14C mRNA

NCBI chr17:23,733,769...23,739,906
Ensembl chr17:23,733,894...23,753,320

G

transmembrane protein 150C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TMEM150C mRNA

NCBI chr14:9,759,028...9,829,588
Ensembl chr14:9,508,515...9,525,298

G

transmembrane protein 154

increases expression

perfluoro-n-nonanoic acid results in increased expression of TMEM154 mRNA

NCBI chr 2:170,015,247...170,054,903
Ensembl chr 2:170,015,184...170,052,481

G

transmembrane protein 156

increases expression

perfluoro-n-nonanoic acid results in increased expression of TMEM156 mRNA

NCBI chr14:43,221,464...43,252,453
Ensembl chr14:43,223,381...43,252,449

G

transmembrane protein 171

increases expression

perfluoro-n-nonanoic acid results in increased expression of TMEM171 mRNA

NCBI chr 2:30,035,278...30,045,996
Ensembl chr 2:30,035,278...30,045,049

G

transmembrane protein 176A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TMEM176A mRNA

NCBI chr 4:79,101,946...79,109,499
Ensembl chr 4:77,774,843...77,778,620

G

transmembrane protein 184A

increases expression

perfluoro-n-nonanoic acid results in increased expression of TMEM184A mRNA

NCBI chr12:14,817,508...14,833,109
Ensembl chr12:14,822,898...14,832,065

G

transmembrane protein 19

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TMEM19 mRNA

NCBI chr 7:50,958,884...50,985,601
Ensembl chr 7:50,958,888...50,986,809

G

transmembrane protein 260

affects methylation

perfluoro-n-nonanoic acid affects the methylation of TMEM260 gene

NCBI chr15:21,734,119...21,804,049
Ensembl chr15:21,734,151...21,806,801

G

transmembrane protein 267

increases expression

perfluoro-n-nonanoic acid results in increased expression of TMEM267 mRNA

NCBI chr 2:51,580,210...51,588,937
Ensembl chr 2:51,581,252...51,587,636

G

transmembrane protein 268

increases expression

perfluoro-n-nonanoic acid results in increased expression of TMEM268 mRNA

NCBI chr 5:81,990,314...82,016,970
Ensembl chr 5:76,977,310...77,001,452

G

transmembrane protein 86B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TMEM86B mRNA

NCBI chr 1:69,218,109...69,220,474
Ensembl chr 1:69,218,608...69,220,124

G

thymopoietin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TMPO mRNA

NCBI chr 7:27,529,977...27,554,980
Ensembl chr 7:25,586,725...25,667,727

G

transmembrane serine protease 2

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] affects the expression of TMPRSS2 mRNA

NCBI chr11:50,403,707...50,443,224
Ensembl chr11:36,934,306...36,973,715

G

transmembrane O-mannosyltransferase targeting cadherins 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of TMTC2 mRNA

NCBI chr 7:40,392,377...40,806,685
Ensembl chr 7:40,394,220...40,807,298

G

tumor necrosis factor

multiple interactions
increases expression
increases secretion

gadolinium chloride inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of TNF protein]; prolinedithiocarbamate inhibits the reaction [TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]]; prolinedithiocarbamate inhibits the reaction [TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]]; prolinedithiocarbamate inhibits the reaction [TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]]; prolinedithiocarbamate inhibits the reaction [TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]]; TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]; TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]; TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]; TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]
perfluoro-n-nonanoic acid results in increased secretion of TNF protein

PMID:19878704 PMID:22648072

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

TNF alpha induced protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of TNFAIP2 mRNA

NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914

G

TNF alpha induced protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of TNFAIP3 mRNA

NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282

G

TNF alpha induced protein 8 like 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TNFAIP8L1 mRNA

NCBI chr 9:988,587...999,342
Ensembl chr 9:988,594...1,002,254

G

TNF receptor superfamily member 11B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TNFRSF11B mRNA

NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:85,566,520...85,594,538

G

TNF receptor superfamily member 12A

increases expression

perfluoro-n-nonanoic acid results in increased expression of TNFRSF12A mRNA

NCBI chr10:13,211,670...13,213,666
Ensembl chr10:12,689,890...12,709,045

G

TNF receptor superfamily member 1A

increases expression

perfluoro-n-nonanoic acid results in increased expression of TNFRSF1A protein

NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:158,150,820...158,163,591

G

TNF receptor superfamily member 1B

increases expression

perfluoro-n-nonanoic acid results in increased expression of TNFRSF1B mRNA

NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:157,070,642...157,104,206

G

TNF receptor superfamily member 21

increases expression

perfluoro-n-nonanoic acid results in increased expression of TNFRSF21 mRNA

NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:17,879,156...17,954,085

G

TNF receptor superfamily member 9

increases expression

perfluoro-n-nonanoic acid results in increased expression of TNFRSF9 mRNA

NCBI chr 5:166,664,494...166,690,834
Ensembl chr 5:161,381,662...161,408,000

G

TNF superfamily member 10

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TNFSF10 mRNA

NCBI chr 2:112,136,550...112,155,903
Ensembl chr 2:110,207,916...110,225,135

G

TNF superfamily member 14

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TNFSF14 mRNA

NCBI chr 9:2,155,270...2,160,100
Ensembl chr 9:2,069,104...2,073,216

G

TNF superfamily member 15

increases expression

perfluoro-n-nonanoic acid results in increased expression of TNFSF15 mRNA

NCBI chr 5:82,150,376...82,171,743
Ensembl chr 5:77,139,878...77,156,228

G

tankyrase 1 binding protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TNKS1BP1 mRNA

NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038

G

translocase of outer mitochondrial membrane 40 like

increases expression

perfluoro-n-nonanoic acid results in increased expression of TOMM40L mRNA

NCBI chr13:86,169,160...86,174,121
Ensembl chr13:83,638,195...83,641,654

G

torsin family 3, member A

increases expression

perfluoro-n-nonanoic acid results in increased expression of TOR3A mRNA

NCBI chr13:68,769,893...68,798,738
Ensembl chr13:68,769,605...68,798,475

G

torsin family 4, member A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TOR4A mRNA

NCBI chr 3:8,004,292...8,007,979
Ensembl chr 3:8,002,023...8,008,042

G

TOX high mobility group box family member 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of TOX3 mRNA

NCBI chr19:32,820,957...32,929,776
Ensembl chr19:16,648,342...16,757,148

G

tumor protein p53 inducible nuclear protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TP53INP2 mRNA

NCBI chr 3:143,881,427...143,890,104
Ensembl chr 3:143,882,021...143,890,097

G

trophoblast glycoprotein

increases expression

perfluoro-n-nonanoic acid results in increased expression of TPBG mRNA

NCBI chr 8:86,793,953...86,797,324
Ensembl chr 8:86,793,749...86,797,741

G

TPD52 like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of TPD52L1 mRNA

NCBI chr 1:27,991,114...28,109,767
Ensembl chr 1:26,172,170...26,291,109

G

TPD52 like 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of TPD52L3 mRNA

NCBI chr 1:227,781,173...227,785,040
Ensembl chr 1:227,773,724...227,784,467

G

tumor protein, translationally-controlled 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TPT1 mRNA

NCBI chr15:57,562,217...57,568,968
Ensembl chr15:51,146,154...51,159,625

G

trehalase

increases expression

perfluoro-n-nonanoic acid results in increased expression of TREH mRNA

NCBI chr 8:44,990,182...45,003,881
Ensembl chr 8:44,990,182...45,003,540

G

tribbles pseudokinase 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of TRIB3 mRNA

NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:140,809,043...140,814,497

G

tripartite motif-containing 25

increases expression

perfluoro-n-nonanoic acid results in increased expression of TRIM25 mRNA

NCBI chr10:74,310,024...74,328,473
Ensembl chr10:73,812,818...73,831,257

G

tripartite motif-containing 31

increases expression

perfluoro-n-nonanoic acid results in increased expression of TRIM31 mRNA

NCBI chr20:1,658,386...1,671,711
Ensembl chr20:1,653,165...1,666,494

G

tripartite motif-containing 32

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TRIM32 mRNA

NCBI chr 5:84,020,604...84,031,483
Ensembl chr 5:78,999,389...79,022,018

G

tripartite motif containing 38

increases expression

perfluoro-n-nonanoic acid results in increased expression of TRIM38 mRNA

NCBI chr17:41,774,419...41,787,709

G

tripartite motif-containing 42

increases expression

perfluoro-n-nonanoic acid results in increased expression of TRIM42 mRNA

NCBI chr 8:97,902,349...97,923,268
Ensembl chr 8:97,902,353...97,923,268

G

tripartite motif-containing 65

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TRIM65 mRNA

NCBI chr10:101,847,822...101,863,052
Ensembl chr10:101,357,937...101,364,971

G

tRNA methyltransferase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of TRMT1 mRNA

NCBI chr19:40,361,583...40,374,971
Ensembl chr19:23,456,756...23,466,956

G

tRNA methyltransferase 10B

increases expression

perfluoro-n-nonanoic acid results in increased expression of TRMT10B mRNA

NCBI chr 5:64,344,491...64,368,175
Ensembl chr 5:59,548,869...59,572,526

G

trophinin associated protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TROAP mRNA

NCBI chr 7:132,111,892...132,121,296
Ensembl chr 7:130,234,544...130,242,365

G

transient receptor potential cation channel, subfamily V, member 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TRPV6 mRNA

NCBI chr 4:71,474,006...71,489,667
Ensembl chr 4:70,507,348...70,523,017

G

TSC22 domain family, member 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TSC22D4 mRNA

NCBI chr12:18,939,150...18,952,008
Ensembl chr12:18,914,398...18,952,008

G

tRNA splicing endonuclease subunit 15

increases expression

perfluoro-n-nonanoic acid results in increased expression of TSEN15 mRNA

NCBI chr13:64,490,216...64,505,591
Ensembl chr13:64,490,218...64,505,617

G

thyroid stimulating hormone subunit beta

decreases secretion

perfluoro-n-nonanoic acid results in decreased secretion of TSHB protein

NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:190,224,676...190,229,559

G

thiosulfate sulfurtransferase like domain containing 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of TSTD2 mRNA

NCBI chr 5:60,371,751...60,415,916
Ensembl chr 5:60,393,454...60,415,916

G

tetratricopeptide repeat domain 39A

increases expression

perfluoro-n-nonanoic acid results in increased expression of TTC39A mRNA

NCBI chr 5:124,165,102...124,204,740
Ensembl chr 5:124,151,760...124,204,973

G

tetratricopeptide repeat domain 39B

increases expression

perfluoro-n-nonanoic acid results in increased expression of TTC39B mRNA

NCBI chr 5:102,649,259...102,754,092
Ensembl chr 5:97,609,392...97,736,270

G

Ttk protein kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TTK mRNA

NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:84,754,315...84,792,651

G

tubulin tyrosine ligase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TTL mRNA

NCBI chr 3:116,298,813...116,328,538
Ensembl chr 3:116,298,797...116,328,538

G

tubulin tyrosine ligase like 11

increases expression

perfluoro-n-nonanoic acid results in increased expression of TTLL11 mRNA

NCBI chr 3:19,109,891...19,335,077
Ensembl chr 3:19,110,284...19,335,969

G

alpha tocopherol transfer protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TTPA mRNA

NCBI chr 5:38,294,415...38,315,471
Ensembl chr 5:33,497,137...33,518,073

G

transthyretin

multiple interactions

perfluoro-n-nonanoic acid affects the reaction [Thyroxine binds to TTR protein]

NCBI chr18:12,216,684...12,225,972
Ensembl chr18:11,943,789...11,951,008

G

tubulin, alpha 1C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TUBA1C mRNA

NCBI chr 7:131,636,974...132,078,589
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr X:130,192,016...130,199,647

G

tubulin, beta 2A class IIa

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TUBB2A mRNA

NCBI chr17:31,002,186...31,006,057
Ensembl chr17:30,747,503...30,800,714

G

tubulin, beta 4B class IVb

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TUBB4B mRNA

NCBI chr 3:28,435,999...28,438,455
Ensembl chr 3:8,037,799...8,040,296

G

tubulin, epsilon 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of TUBE1 mRNA

NCBI chr20:42,552,390...42,570,324
Ensembl chr20:42,552,437...42,570,314

G

taxilin gamma

increases expression

perfluoro-n-nonanoic acid results in increased expression of TXLNG mRNA

NCBI chr X:31,864,111...31,912,931
Ensembl chr X:31,864,111...31,912,926

G

thioredoxin domain containing 16

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TXNDC16 mRNA

NCBI chr15:18,351,688...18,425,833
Ensembl chr15:18,351,694...18,425,722

G

thioredoxin interacting protein

increases expression

perfluoro-n-nonanoic acid results in increased expression of TXNIP mRNA

PMID:23567314 PMID:32588087

NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:184,092,991...184,096,886

G

tyrosine kinase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TYK2 mRNA

NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:19,641,884...19,667,044

G

TYRO3 protein tyrosine kinase

increases expression

perfluoro-n-nonanoic acid results in increased expression of TYRO3 mRNA

NCBI chr 3:127,231,468...127,254,806
Ensembl chr 3:106,777,635...106,797,142

G

trypsin like peroxisomal matrix peptidase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of TYSND1 mRNA

NCBI chr20:29,637,942...29,646,492
Ensembl chr20:29,638,277...29,643,995

G

tRNA-yW synthesizing protein 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of TYW5 mRNA

NCBI chr 9:58,961,100...58,979,188
Ensembl chr 9:58,961,106...58,979,188

G

ubiquitin conjugating enzyme E2 Q1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of UBE2Q1 mRNA

NCBI chr 2:177,496,480...177,505,631
Ensembl chr 2:175,198,873...175,207,942

G

ubiquitin-conjugating enzyme E2T

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of UBE2T mRNA

NCBI chr13:48,955,166...48,965,668
Ensembl chr13:46,403,375...46,414,835

G

ubiquitination factor E4B

increases expression

perfluoro-n-nonanoic acid results in increased expression of UBE4B mRNA

NCBI chr 5:159,766,829...159,870,509
Ensembl chr 5:159,766,829...159,870,509

G

UbiA prenyltransferase domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of UBIAD1 mRNA

NCBI chr 5:164,139,714...164,167,777
Ensembl chr 5:158,868,672...158,880,271

G

UDP glucuronosyltransferase family 2 member A3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of UGT2A3 mRNA

NCBI chr14:20,851,970...20,869,974
Ensembl chr14:20,572,808...20,590,729

G

UDP glucuronosyltransferase family 2 member B7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of UGT2B7 mRNA

NCBI chr14:21,251,535...21,274,451
Ensembl chr14:20,896,682...20,919,604

G

unc-51 like kinase 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ULK3 mRNA

NCBI chr 8:57,992,396...58,000,220
Ensembl chr 8:57,992,723...57,999,467

G

unc-5 netrin receptor B

increases expression

perfluoro-n-nonanoic acid results in increased expression of UNC5B mRNA

NCBI chr20:29,240,639...29,307,270
Ensembl chr20:28,697,726...28,764,537

G

beta-ureidopropionase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of UPB1 mRNA

NCBI chr20:13,216,693...13,243,016
Ensembl chr20:13,217,258...13,243,590

G

UPF3A, regulator of nonsense mediated mRNA decay

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of UPF3A mRNA

NCBI chr16:82,459,651...82,470,686
Ensembl chr16:75,757,441...75,769,345

G

uridine phosphorylase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of UPP1 mRNA

NCBI chr14:88,023,155...88,043,036
Ensembl chr14:83,809,960...83,829,462

G

ubiquinol-cytochrome c reductase, complex III subunit XI

increases expression

perfluoro-n-nonanoic acid results in increased expression of UQCR11 mRNA

NCBI chr 7:9,305,042...9,309,753
Ensembl chr 7:9,305,058...9,309,750

G

URB2 ribosome biogenesis homolog

increases expression

perfluoro-n-nonanoic acid results in increased expression of URB2 mRNA

NCBI chr19:68,908,466...68,934,058
Ensembl chr19:52,011,112...52,036,597

G

ubiquitin related modifier 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of URM1 mRNA

NCBI chr 3:13,100,340...13,117,064
Ensembl chr 3:13,092,200...13,117,642
Ensembl chr 3:13,092,200...13,117,642

G

ubiquitin specific peptidase 36

increases expression

perfluoro-n-nonanoic acid results in increased expression of USP36 mRNA

NCBI chr10:103,497,349...103,528,877
Ensembl chr10:103,497,349...103,528,877

G

integral membrane transport protein UST5r

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of SLC22A25 mRNA

NCBI chr 1:205,210,558...205,286,868
Ensembl chr 1:205,211,034...205,286,718

G

UTP15, small subunit processome component

increases expression

perfluoro-n-nonanoic acid results in increased expression of UTP15 mRNA

NCBI chr 2:29,594,405...29,612,819
Ensembl chr 2:29,594,941...29,612,773

G

UTP20 small subunit processome component

increases expression

perfluoro-n-nonanoic acid results in increased expression of UTP20 mRNA

NCBI chr 7:25,022,029...25,103,024
Ensembl chr 7:23,134,637...23,215,632

G

UTP25 small subunit processome component

increases expression

perfluoro-n-nonanoic acid results in increased expression of UTP25 mRNA

NCBI chr13:104,630,390...104,651,681
Ensembl chr13:104,630,391...104,651,662

G

UTP4 small subunit processome component

increases expression

perfluoro-n-nonanoic acid results in increased expression of UTP4 mRNA

NCBI chr19:51,696,437...51,730,323
Ensembl chr19:34,792,457...34,820,550

G

vascular endothelial growth factor A

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of VEGFA protein
perfluoro-n-nonanoic acid results in increased expression of VEGFA mRNA

PMID:32588087 PMID:32916415

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641

G

villin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of VIL1 mRNA

NCBI chr 9:83,440,248...83,467,963
Ensembl chr 9:75,991,141...76,018,858

G

villin-like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of VILL mRNA

NCBI chr 8:118,776,718...118,794,983
Ensembl chr 8:118,776,742...118,794,983

G

vimentin

increases expression

perfluoro-n-nonanoic acid results in increased expression of VIM mRNA

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187

G

vanin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of VNN1 mRNA

NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:21,537,094...21,547,395

G

VPS33A core subunit of CORVET and HOPS complexes

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of VPS33A mRNA

NCBI chr12:38,685,484...38,710,668
Ensembl chr12:33,024,650...33,051,393

G

VPS37B subunit of ESCRT-I

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of VPS37B mRNA

NCBI chr12:38,220,973...38,249,935
Ensembl chr12:32,560,047...32,589,014

G

visinin-like 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of VSNL1 mRNA

NCBI chr 6:39,757,721...39,878,556
Ensembl chr 6:34,038,642...34,159,479

G

von Willebrand factor A domain containing 8

increases expression

perfluoro-n-nonanoic acid results in increased expression of VWA8 mRNA

NCBI chr15:54,252,703...54,576,871
Ensembl chr15:54,252,584...54,576,870

G

von Willebrand factor C domain containing 2 like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of VWC2L mRNA

NCBI chr 9:72,252,793...72,448,543
Ensembl chr 9:72,253,387...72,444,839

G

tryptophanyl-tRNA synthetase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of WARS1 mRNA

NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:127,776,090...127,807,269

G

WD repeat domain 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of WDR3 mRNA

NCBI chr 2:187,505,816...187,528,432
Ensembl chr 2:187,505,816...187,528,432

G

WD repeat domain 43

increases expression

perfluoro-n-nonanoic acid results in increased expression of WDR43 mRNA

NCBI chr 6:23,845,499...23,884,846
Ensembl chr 6:23,845,499...23,884,846

G

WD repeat domain 46

increases expression

perfluoro-n-nonanoic acid results in increased expression of WDR46 mRNA

NCBI chr20:4,937,845...4,945,796
Ensembl chr20:4,937,847...4,946,535

G

WD repeat domain 54

increases expression

perfluoro-n-nonanoic acid results in increased expression of WDR54 mRNA

NCBI chr 4:117,212,677...117,236,456
Ensembl chr 4:115,654,968...115,661,562

G

WD repeat domain 72

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of WDR72 mRNA

NCBI chr 8:83,718,897...83,902,128
Ensembl chr 8:74,838,318...75,018,229

G

WD repeat domain 74

increases expression

perfluoro-n-nonanoic acid results in increased expression of WDR74 mRNA

NCBI chr 1:205,631,769...205,636,558
Ensembl chr 1:205,631,824...205,636,563

G

WEE1 G2 checkpoint kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of WEE1 mRNA

NCBI chr 1:173,605,609...173,632,450
Ensembl chr 1:164,174,779...164,197,688

G

WAP four-disulfide core domain 8

increases expression

perfluoro-n-nonanoic acid results in increased expression of WFDC8 mRNA

NCBI chr 3:153,323,503...153,339,849
Ensembl chr 3:153,324,413...153,339,842

G

WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of WFIKKN2 mRNA

NCBI chr10:79,682,459...79,688,553
Ensembl chr10:79,186,647...79,191,657

G

Wnt inhibitory factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of WIF1 mRNA

NCBI chr 7:58,433,326...58,503,853
Ensembl chr 7:56,548,053...56,618,360

G

WIZ zinc finger

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of WIZ mRNA

NCBI chr 7:12,017,374...12,045,812
Ensembl chr 7:11,367,035...11,395,490

G

WNK lysine deficient protein kinase 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of WNK3 mRNA

NCBI chr X:20,156,260...20,299,252
Ensembl chr X:20,157,041...20,296,821

G

Wnt family member 10B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of WNT10B mRNA

NCBI chr 7:131,801,046...131,806,850
Ensembl chr 7:129,922,088...129,927,892

G

WT1 transcription factor

increases expression

perfluoro-n-nonanoic acid results in increased expression of WT1 mRNA; perfluoro-n-nonanoic acid results in increased expression of WT1 protein

NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:91,567,001...91,613,643

G

XIAP associated factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of XAF1 mRNA

NCBI chr10:57,415,935...57,428,348
Ensembl chr10:56,917,121...56,929,770

G

xanthine dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of XDH mRNA

NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:21,530,113...21,592,268

G

XK related 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of XKR5 mRNA

NCBI chr16:70,874,983...70,892,972
Ensembl chr16:70,875,093...70,892,967

G

XK related, X-linked

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of XKRX mRNA

NCBI chr X:97,341,158...97,353,175
Ensembl chr X:97,341,152...97,354,759

G

exportin 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of XPO5 mRNA

NCBI chr 9:22,237,760...22,275,745
Ensembl chr 9:14,740,182...14,778,171

G

exportin for tRNA

increases expression

perfluoro-n-nonanoic acid results in increased expression of XPOT mRNA

NCBI chr 7:58,997,025...59,037,506
Ensembl chr 7:57,111,536...57,152,099

G

YAE1 maturation factor of ABCE1

increases expression

perfluoro-n-nonanoic acid results in increased expression of YAE1 mRNA

NCBI chr17:47,027,033...47,033,549
Ensembl chr17:47,027,019...47,033,546

G

tyrosyl-tRNA synthetase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of YARS1 mRNA

NCBI chr 5:146,820,163...146,848,377
Ensembl chr 5:141,535,759...141,563,833

G

YdjC chitooligosaccharide deacetylase homolog

increases expression

perfluoro-n-nonanoic acid results in increased expression of YDJC mRNA

NCBI chr11:97,338,529...97,348,909
Ensembl chr11:83,841,306...83,846,336

G

yippee-like 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of YPEL3 mRNA

NCBI chr 1:181,384,385...181,387,706
Ensembl chr 1:181,384,357...181,387,705

G

yrdC N(6)-threonylcarbamoyltransferase domain containing

increases expression

perfluoro-n-nonanoic acid results in increased expression of YRDC mRNA

NCBI chr 5:137,110,244...137,115,127
Ensembl chr 5:137,110,279...137,115,120

G

YTH N6-methyladenosine RNA binding protein C1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of YTHDC1 mRNA

NCBI chr14:21,185,438...21,215,934
Ensembl chr14:21,185,440...21,216,028

G

zeta chain of T cell receptor associated protein kinase 70

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZAP70 mRNA

NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:38,989,750...39,011,700

G

zinc finger and BTB domain containing 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ZBTB2 mRNA

NCBI chr 1:40,827,457...40,846,733
Ensembl chr 1:40,827,457...40,846,594

G

zinc finger and BTB domain containing 7B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZBTB7B mRNA

NCBI chr 2:177,093,569...177,111,894
Ensembl chr 2:174,797,453...174,814,236

G

zinc finger CCCH-type containing 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZC3H4 mRNA

NCBI chr 1:77,106,309...77,143,827
Ensembl chr 1:77,106,250...77,142,691

G

zinc finger CCCH type containing 8

increases expression

perfluoro-n-nonanoic acid results in increased expression of ZC3H8 mRNA

NCBI chr 3:136,629,998...136,646,998
Ensembl chr 3:116,176,798...116,193,787

G

zinc finger DHHC-type palmitoyltransferase 12

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZDHHC12 mRNA

NCBI chr 3:33,761,338...33,764,207
Ensembl chr 3:13,363,504...13,366,474

G

zinc finger DHHC-type palmitoyltransferase 15

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZDHHC15 mRNA

NCBI chr X:73,633,977...73,767,451
Ensembl chr X:69,574,124...69,701,756

G

zinc finger E-box binding homeobox 1

multiple interactions
increases expression

PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of ZEB1 mRNA]

NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214

G

zinc finger E-box binding homeobox 2

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of ZEB2 mRNA
PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of ZEB2 mRNA]

PMID:32534105 PMID:32588087

NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:29,218,301...29,345,157

G

zinc finger AN1-type containing 2A

increases expression

perfluoro-n-nonanoic acid results in increased expression of ZFAND2A mRNA

NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677

G

zinc finger protein 146

increases expression

perfluoro-n-nonanoic acid results in increased expression of ZNF146 mRNA

NCBI chr 1:85,409,570...85,421,835
Ensembl chr 1:85,409,373...85,436,275

G

zinc finger protein 286A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZNF286A mRNA

NCBI chr10:47,450,469...47,461,267
Ensembl chr10:47,450,469...47,463,258

G

zinc finger protein 422

increases expression

perfluoro-n-nonanoic acid results in increased expression of ZNF22 mRNA

NCBI chr 4:151,558,254...151,565,730
Ensembl chr 4:149,885,600...149,893,257

G

zinc finger protein 541

increases expression

perfluoro-n-nonanoic acid results in increased expression of ZNF541 mRNA

NCBI chr 1:85,878,329...85,914,754
Ensembl chr 1:76,750,236...76,786,567

G

zinc finger protein 593

increases expression

perfluoro-n-nonanoic acid results in increased expression of ZNF593 mRNA

NCBI chr 5:146,462,670...146,464,998
Ensembl chr 5:146,462,670...146,465,198

G

zinc finger protein 609

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZNF609 mRNA

NCBI chr 8:66,214,553...66,349,319
Ensembl chr 8:66,214,555...66,317,977

G

zinc finger protein 619

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZNF850 mRNA

NCBI chr 1:91,148,016...91,167,764
Ensembl chr 1:91,148,121...91,166,403

G

zinc finger protein 628

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZNF628 mRNA

NCBI chr 1:68,913,600...68,921,186
Ensembl chr 1:68,910,401...68,921,243

G

zinc finger protein 629

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZNF629 mRNA

NCBI chr 1:182,217,499...182,258,585
Ensembl chr 1:182,210,935...182,230,016

G

zinc finger protein 703

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZNF703 mRNA

NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677

G

zinc finger protein 770

increases expression

perfluoro-n-nonanoic acid results in increased expression of ZNF770 mRNA

NCBI chr 3:100,963,430...100,971,663
Ensembl chr 3:100,963,427...100,971,684

G

zinc finger protein 873

increases expression

perfluoro-n-nonanoic acid results in increased expression of ZNF441 mRNA

NCBI chr 7:7,926,951...7,959,822
Ensembl chr 7:7,926,957...7,951,803

G

zinc finger FYVE-type containing 28

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZFYVE28 mRNA

NCBI chr14:80,692,997...80,778,606
Ensembl chr14:76,468,424...76,554,039

G

zinc finger CCCH-type and G-patch domain containing

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZGPAT mRNA

NCBI chr 3:188,851,376...188,867,914
Ensembl chr 3:168,473,981...168,490,380

G

zinc finger, GRF-type containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZGRF1 mRNA

NCBI chr 2:216,012,911...216,075,608
Ensembl chr 2:216,013,005...216,074,750

G

zinc finger with KRAB and SCAN domains 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZKSCAN5 mRNA

NCBI chr12:9,384,561...9,405,763
Ensembl chr12:9,384,571...9,405,881

G

zinc finger, matrin-type 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZMAT1 mRNA

NCBI chr X:102,461,621...102,520,818
Ensembl chr X:98,168,456...98,199,733

G

zinc and ring finger 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZNRF4 mRNA

NCBI chr 9:1,440,444...1,441,632
Ensembl chr 9:1,353,306...1,354,584

G

zona pellucida-like domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZPLD1 mRNA

NCBI chr11:45,482,883...45,524,555
Ensembl chr11:45,482,891...45,522,385

G

ZPR1 zinc finger

increases expression

perfluoro-n-nonanoic acid results in increased expression of ZPR1 mRNA

NCBI chr 8:55,461,839...55,471,413
Ensembl chr 8:46,565,146...46,574,719

G

zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZRSR2 mRNA

NCBI chr X:34,179,279...34,201,989
Ensembl chr X:30,547,536...30,570,125

G

zinc finger and SCAN domain containing 21

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZSCAN21 mRNA

NCBI chr12:22,112,204...22,142,506
Ensembl chr12:16,998,538...17,013,506

G

zinc finger, SWIM-type containing 7

increases expression

perfluoro-n-nonanoic acid results in increased expression of ZSWIM7 mRNA

NCBI chr10:46,953,311...46,969,800
Ensembl chr10:46,957,525...46,969,671

G

ZW10 interacting kinetochore protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ZWINT mRNA

NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,938,157...15,953,957

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19909
role	19880
biological role	19878
xenobiotic	18757
perfluorononanoic acid	1612
Path 2
Term	Annotations
CHEBI ontology	19909
subatomic particle	19907
composite particle	19907
hadron	19907
baryon	19907
nucleon	19907
atomic nucleus	19907
atom	19907
main group element atom	19846
p-block element atom	19846
carbon group element atom	19784
carbon atom	19781
organic molecular entity	19781
heteroorganic entity	19540
organochalcogen compound	19301
organooxygen compound	19216
carbon oxoacid	18696
carboxylic acid	18693
monocarboxylic acid	18028
fatty acid	16860
saturated fatty acid	16575
straight-chain saturated fatty acid	16110
nonanoic acid	1700
perfluorononanoic acid	1612

paths to the root