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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69219
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh2
Name: aldehyde dehydrogenase 2 family member
Acc ID: CHEBI:16389
Term: ubiquinones
Definition: Any benzoquinone derived from 2,3-dimethoxy-5-methylbenzoquinone; one of a group of naturally occurring homologues. The redox-active quinoid moiety usually carries a polyprenoid side chain at position 6, the number of isoprenoid units in which is species-specific. Ubiquinones are involved in the control of mitochondrial electron transport, and are also potent anti-oxidants.
Chemical ID: MESH:D014451
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh2multiple interactionsISOAldh2 (Mus musculus)15036805RGDubiquinones decrease 4-hydroxynonenal-Aldh2 protein adduct formation; decrease acylation, nitrosylation, S-nitrosylation, and nitration of Aldh2 protein in mouse liver 
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