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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69168
Species: Homo sapiens
RGD Object: Gene
Symbol: PPARG
Name: peroxisome proliferator activated receptor gamma
Acc ID: CHEBI:3139
Term: bleomycin A2
Definition: A bleomycin that has formula C55H84N17O21S3.
Chemical ID: MESH:D001761
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPARGmultiple interactionsEXP 6480464CTDBerberine inhibits the reaction [Bleomycin binds to PPARG protein]PMID:29408570
PPARGdecreases expressionISOPparg (Mus musculus)6480464CTDBleomycin results in decreased expression of PPARG mRNA; Bleomycin results in decreased expression of PPARG proteinPMID:19147827 PMID:27153807
PPARGmultiple interactionsISOPparg (Mus musculus)6480464CTDlenabasum inhibits the reaction [Bleomycin results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [Bleomycin results in decreased expression of PPARG mRNA]PMID:19147827 PMID:27153807
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