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GENE - TERM ANNOTATION REPORT

RGD ID: 69079
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Wnt7a
Name: Wnt family member 7A
Acc ID: GO:0060856
Term: establishment of blood-brain barrier
Definition: Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
Definition Source(s): GOC:aruk, GOC:dph, GOC:sart, PMID:20080302, PMID:30280653
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Wnt7aacts_upstream_of_or_withinISOWnt7a (Mus musculus)1624291RGDMGI:102570 MGI:108520 PMID:30478038

PMID:30478038
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