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GENE - TERM ANNOTATION REPORT

RGD ID: 69051
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfb1
Name: transforming growth factor, beta 1
Acc ID: GO:0005578
Term: proteinaceous extracellular matrix
Definition: A protein-containing extracellular matrix that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. In metazoans it consists mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that form a sheet underlying or overlying cells such as endothelial and epithelial cells. The components are secreted by cells in the vicinity.
Definition Source(s): GOC:BHF, GOC:BHF_miRNA, GOC:mtg_sensu, ISBN:0198547684, PMID:21123617
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
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