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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69022
Species: Homo sapiens
RGD Object: Gene
Symbol: FDPS
Name: farnesyl diphosphate synthase
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FDPSaffects expressionISOFdps (Rattus norvegicus)6480464CTDpirinixic acid affects the expression of FDPS mRNAPMID:19483382
FDPSaffects expressionISOFdps (Mus musculus)6480464CTDpirinixic acid affects the expression of FDPS mRNAPMID:19136022
FDPSdecreases expressionISOFdps (Mus musculus)6480464CTDpirinixic acid results in decreased expression of FDPS mRNAPMID:18445702
FDPSincreases expressionISOFdps (Rattus norvegicus)6480464CTDpirinixic acid results in increased expression of FDPS mRNAPMID:19162173
FDPSincreases expressionISOFdps (Mus musculus)6480464CTDpirinixic acid results in increased expression of FDPS mRNA; pirinixic acid results in increased expression of FDPS proteinPMID:15226431 PMID:15302862 PMID:18467677 PMID:20813756 PMID:20936131
FDPSmultiple interactionsISOFdps (Mus musculus)6480464CTDPPARA protein promotes the reaction [pirinixic acid results in increased expression of FDPS mRNA]PMID:18467677
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