GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL13 | decreases response to substance | EXP | | 6480464 | CTD | fidarestat results in decreased susceptibility to IL13 protein | PMID:21203431 | IL13 | multiple interactions | EXP | | 6480464 | CTD | fidarestat inhibits the reaction [IL13 protein results in increased expression of and results in increased secretion of MUC5AC protein]; fidarestat inhibits the reaction [IL13 protein results in increased expression of MUC5AC mRNA]; fidarestat inhibits the reaction [IL13 protein results in increased expression of SPDEF mRNA]; fidarestat inhibits the reaction [IL13 protein results in increased expression of SPDEF protein]; fidarestat inhibits the reaction [IL13 protein results in increased phosphorylation of JAK1 protein]; fidarestat inhibits the reaction [IL13 protein results in increased phosphorylation of MAPK1 protein]; fidarestat inhibits the reaction [IL13 protein results in increased phosphorylation of MAPK3 protein]; fidarestat inhibits the reaction [IL13 protein results in increased phosphorylation of STAT6 protein] | PMID:21203431 | IL13 | multiple interactions | ISO | Il13 (Mus musculus) | 6480464 | CTD | fidarestat inhibits the reaction [Plant Extracts results in increased expression of IL13 mRNA] | PMID:21203431 | | ||||||||||||||||||||||
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