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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68620
Species: Mus musculus
RGD Object: Gene
Symbol: Dio2
Name: deiodinase, iodothyronine, type II
Acc ID: CHEBI:30614
Term: benzo[a]pyrene diol epoxide I
Definition: An epoxide that has formula C20H14O3.
Chemical ID: MESH:D015123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dio2decreases expressionISODIO2 (Homo sapiens)6480464CTD7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of DIO2 mRNAPMID:20018196 PMID:20382639
Dio2increases expressionISODIO2 (Homo sapiens)6480464CTD7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of DIO2 mRNAPMID:19150397
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