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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68516
Species: Mus musculus
RGD Object: Gene
Symbol: Lrat
Name: lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
Acc ID: CHEBI:75170
Term: zaragozic acid A
Definition: A polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase.
Chemical ID: MESH:C075117
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lratincreases expressionEXP 6480464CTDsqualestatin 1 results in increased expression of LRAT mRNAPMID:27225895
Lratdecreases expressionISOLrat (Rattus norvegicus)6480464CTDsqualestatin 1 results in decreased expression of LRAT mRNAPMID:27225895
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