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GENE - TERM ANNOTATION REPORT

RGD ID: 68515
Species: Homo sapiens
RGD Object: Gene
Symbol: LRAT
Name: lecithin retinol acyltransferase
Acc ID: GO:0047173
Term: phosphatidylcholine-retinol O-acyltransferase activity
Definition: Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester + apo--[retinol-binding protein]. Recognizes the substrate both in free form and when bound to cellular-retinol-binding-protein, but has higher affinity for the bound form.
Definition Source(s): RHEA:17469
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LRAT ISOLrat (Rattus norvegicus)9068941RGD PMID:14642897 PMID:2253789 PMID:8460936 PMID:9244401 REF_RGD_ID:1599829 REF_RGD_ID:1599831 REF_RGD_ID:1599832 REF_RGD_ID:6484737
LRATenablesIEAUniProtKB:Q9JI60 or UniProtKB:Q9JI61 or ensembl:ENSMUSP00000029632 or ensembl:ENSRNOP00000035053150520179Ensembl GO_REF:0000107
LRATenablesIBAMGI:1891259 or PANTHER:PTN002928202 or Lrat (Rattus norvegicus) or UniProtKB:O95237 or ZFIN:ZDB-GENE-060810-31150520179GO_Central GO_REF:0000033
LRATenablesIEAInterPro:IPR042288150520179InterPro GO_REF:0000002
LRATenablesIEARHEA:17469150520179RHEA GO_REF:0000116
LRATenablesTAS 150520179Reactome Reactome:R-HSA-975608
LRATenablesIDA 150520179UniProt PMID:10819989

PMID:10819989
LRATenablesIEAEC:2.3.1.135150520179UniProt GO_REF:0000003
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