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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68433
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aqp9
Name: aquaporin 9
Acc ID: CHEBI:29866
Term: arsenite(3-)
Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid.
Chemical ID: MESH:C015001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aqp9increases response to substanceISOAqp9 (Mus musculus)6480464CTDAQP9 protein results in increased susceptibility to arsenitePMID:19341753
Aqp9increases response to substanceISOAQP9 (Homo sapiens)6480464CTDAQP9 protein results in increased susceptibility to arsenitePMID:29566083
Aqp9increases uptakeISOAqp9 (Mus musculus)6480464CTDAQP9 protein results in increased uptake of arsenitePMID:19341753
Aqp9increases uptakeISOAQP9 (Homo sapiens)6480464CTDAQP9 protein results in increased uptake of arsenitePMID:11972053
Aqp9multiple interactionsISOAqp9 (Mus musculus)6480464CTDSorbitol inhibits the reaction [AQP9 protein results in increased uptake of arsenite]PMID:19341753
Aqp9multiple interactionsISOAQP9 (Homo sapiens)6480464CTDarsenite inhibits the reaction [AQP9 protein results in increased uptake of Lactic Acid]; arsenite inhibits the reaction [AQP9 protein results in increased uptake of Selenic Acid analog]; arsenite inhibits the reaction [AQP9 protein results in increased uptake of Selenious Acid]PMID:28798983
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