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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68371
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mtor
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:80852
Term: Morroniside
Definition: A glycoside that has formula C17H26O11.
Chemical ID: MESH:C488401
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mtormultiple interactionsEXP 6480464CTDmorroniside inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of MTOR protein]PMID:32954801
Mtorincreases activityISOMtor (Mus musculus)6480464CTDmorroniside results in increased activity of MTOR proteinPMID:35957534
Mtormultiple interactionsISOMtor (Mus musculus)6480464CTDMTOR inhibits the reaction [morroniside results in increased expression of ATG13 protein]; MTOR inhibits the reaction [morroniside results in increased expression of BECN1 protein]PMID:35957534
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