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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 67383
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkcd
Name: protein kinase C, delta
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkcdmultiple interactionsISOPRKCD (Homo sapiens)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased activity of and results in increased localization of PRKCD protein]; bisindolylmaleimide II inhibits the reaction [Oxygen deficiency results in increased activity of and results in increased localization of PRKCD protein]; Oxygen deficiency results in increased activity of and results in increased localization of PRKCD protein; PRKCD protein promotes the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]; PRKCD protein promotes the reaction [Oxygen deficiency results in increased expression of HSF1 mRNA]; Quercetin inhibits the reaction [Oxygen deficiency results in increased activity of and results in increased localization of PRKCD protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Oxygen deficiency results in increased activity of and results in increased localization of PRKCD protein]; Wortmannin inhibits the reaction [Oxygen deficiency results in increased activity of and results in increased localization of PRKCD protein]PMID:11424089
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