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GENE - TERM ANNOTATION REPORT

RGD ID: 628895
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aurka
Name: aurora kinase A
Acc ID: GO:0007100
Term: mitotic centrosome separation
Definition: Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
Definition Source(s): ISBN:0815316194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aurkaacts_upstream_of_or_withinISOAurka (Mus musculus)1624291RGDMGI:1932915 MGI:3836423 PMID:17060449 PMID:19075002

PMID:17060449 PMID:19075002
Aurkainvolved_inIEAUniProtKB:P97477 or ensembl:ENSMUSP000000289971600115EnsemblGO_REF:0000107

GO_REF:0000107
Aurkainvolved_inIEAInterPro:IPR0306111600115InterProGO_REF:0000002

GO_REF:0000002
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