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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628837
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Actb
Name: actin, beta
Acc ID: CHEBI:132607
Term: mono(2-ethyl-5-hydroxyhexyl) phthalate
Definition: A phthalic acid monoester obtained by formal condensation of one of the carboxy groups of phthalic acid with the primary hydroxy group of 2-ethylhexane-1,5-diol
Chemical ID: MESH:C479069
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Actbaffects expressionISOACTB (Homo sapiens)6480464CTDmono(2-ethyl-5-hydroxyhexyl) phthalate affects the expression of ACTB mRNAPMID:38992643
Actbmultiple interactionsISOACTB (Homo sapiens)6480464CTD[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate metabolite co-treated with monoethyl phthalate co-treated with monobutyl phthalate] results in increased expression of ACTB mRNA; [mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with methylparaben] results in increased expression of ACTB mRNAPMID:38992643
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