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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptk2b
Name: protein tyrosine kinase 2 beta
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptk2bincreases expressionISOPTK2B (Homo sapiens)6480464CTDTretinoin results in increased expression of PTK2B mRNAPMID:15498508 PMID:15894607 PMID:16140955 PMID:33167477
Ptk2bmultiple interactionsISOPTK2B (Homo sapiens)6480464CTD[Tretinoin co-treated with CXCL12 protein] results in increased expression of PTK2B proteinPMID:17656649
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